1,4-dichloro-2-nitrobenzene

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

17-07-2017 – 21-07-2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

other: spectrophotometric analytical method

Principles of method if other than guideline:

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101.

GLP compliance:

no

Type of method:

other: spectrophotometric analytical method

Specific details on test material used for the study:

Details on test material
- Name of test material (as cited in study report): 2,5-Dichloronitrobenzene
- Molecular formula (if other than submission substance): C6-H3-Cl2-N-O2
- Molecular weight (if other than submission substance): 192.001
- Smiles notation (if other than submission substance): c1(c(ccc(c1)Cl)Cl)[N+](=O)[O-]
- InChl (if other than submission substance): 1S/C6H3Cl2NO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:Organic
- Physical state:Solid

Key result

Water solubility:

84.095 mg/L

Conc. based on:

test mat.

Incubation duration:

72 h

Temp.:

25 °C

Remarks on result:

other: No other detail available

Obseravtionn Table:

Sample stirring	Concentration obtained on	Dilution factor	Solubility value obtained
	the basis of standard curve		(mg/L)
24 hour	-	-	-
48 hour	7.759 mg/L	10	77.59 mg/L
72 hour	9.060 mg/L	10	90.6 mg/L

Conclusions:

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done by spectrophotometric method. The water solubility was determine to be 84.095 mg/L at 25°C.

Executive summary:

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The water solubility was determine to be 84.095 mg/L at 25°C.

Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

Description of key information

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The water solubility was determined to be 84.095 mg/L at 25°C. Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

Key value for chemical safety assessment

Water solubility:

84.095 mg/L

Additional information

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The water solubility was determined to be 84.095 mg/L at 25°C. Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

The water solubility of chemical 1,4-dichloro-2-nitrobenzene is determine to be 83 mg/L at 20 deg C. Thus chemical consider to be slightly soluble.

Thus based on the above both studies from experimental study report and other database, chemical consider to be slightly soluble.