Peracetic acid

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Acceptable, well documented publication

Qualifier:

no guideline available

Guideline:

other: No guideline available at the time of publication

GLP compliance:

no

Boiling pt.:

>= 105 - <= 110 °C

Remarks on result:

other: From comparison with Swerm (1970, see reference), it may be concluded that the boiling point of 105-110°C refers to atmospheric pressure.

None

Conclusions:

The boiling point atmospheric pressure is 105-110°C.

Executive summary:

The boiling point atmospheric pressure is 105-110°C and is in line with other study results.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Peer reviewed data

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

not specified

GLP compliance:

no

Type of method:

other: EU Method A.2

Boiling pt.:

>= 99 - <= 105 °C

Remarks on result:

other: 5% equilibrium solutions

Boiling pt.:

> 100 °C

Remarks on result:

other: 15% equilibrium solutions

Boiling pt.:

> 105 °C

Remarks on result:

other: 35% equilibrium solution

None

Conclusions:

The boiling point atmospheric pressure is > 99-105 °C for both 5% and 15% peracetic acid.

Executive summary:

The boiling point atmospheric pressure is > 99 -105 °C for both 5% and 15% peracetic acid and is in line with other study results.

Reference 3

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

105 °C

Atm. press.:

1 000.5 hPa

Decomposition:

no

The DSC measurements were performed twice, using crucible lids with one hole of 50 µm to determine a possible boiling point more precisely. The small hole causes the generation of a defined atmosphere at constant pressure inside the crucible and allows measurements at near equilibrium conditions, thus preventing evaporation of the test material before reaching the boiling point. The measurements were stopped before the temperature had reached 250 °C. In the first run the crucible cracked open at 127 °C, due to overpressure, probably caused by a closed up hole. The second run was stopped at 145 °C, because the heat flow curve indicated decomposition (exothermic). The sample had lost approx. 98.5 % of its mass at the end of the 2nd measurement

without visible residue.

Interpretation of the differential scanning calorimeter curve: The DSC-curves show a glass transition, followed by 2 crystallization peaks at -86 °C and -77 °C. Upon further heating a threefold melting peak in the range of approx. -73 °C to -47 °C is registered. The melting temperature is commonly defined by the extrapolated onset temperature of -73 °C. At approximately 50 °C an exothermic heat flow indicates a beginning decomposition reaction. An endothermic peak at 114°C with an extrapolated onset temperature of 105 °C indicates the boiling point. The curve of the first run shows this peak only partially (closed up hole). A preliminary thermogravimetric measurement was performed over a temperature range from room temperature to 370 °C. A single step is registered with a maximum at 105 °C and a total mass loss of 87.5 %. The thermogravimetric curve and the DSC curves cannot be compared directly, since the thermogravimetric measurement was carried out in an open crucible (perforated lid with several holes), where evaporation takes place long before the boiling point is reached. Copies of the differential scanning calorimeter curves and the preliminary thermogravimetric curve of the test item are attached.

Conclusions:

Boiling point of a 15.37 % peracetic acid, 25.56 % hydrogen peroxide and 14.27 % acetic acid solution in water is 105 °C.

Executive summary:

The boiling temperature of the test item was determined by differential scanning calorimetry according to EEC-Directive 92/69 EEC, Part A, Methods for the determination of physicochemical properties, A. 2 "Boiling temperature", EEC Publication No. L383, December 1992.

Boiling temperature: 105 °C

Reference 4

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Peer reviewed data

Guideline:

other: calculation method

Deviations:

not applicable

GLP compliance:

no

Type of method:

other: calculation

Boiling pt.:

>= 20 - <= 30 °C

Atm. press.:

10 - 20 mm Hg

Boiling pt.:

25 °C

Atm. press.:

12 mm Hg

Boiling pt.:

>= 30 - <= 31 °C

Atm. press.:

26 mm Hg

Boiling pt.:

>= 35 - <= 36 °C

Atm. press.:

29 mm Hg

Key result

Boiling pt.:

110 °C

Atm. press.:

760 mm Hg

Remarks on result:

other: Calculated

PAA solutions should never be distilled at atmospheric pressure because they are likely to explode or to undergo violent decomposition. The distillation pressure should be maintained below 30 mmHg.

Conclusions:

Boiling point at various pressures:
20 — 30 °C 10 — 20 mm Hg
25 °C 12 mm Hg
30 — 31 °C 26 mm Hg
35 — 36 °C 29 mm Hg
110 °C 760 mm Hg Calculated

Executive summary:

Pure peracetic acid explodes when heated to about 100 to 110 °C. In addition contact with metal ions or organic materials also can cause explosions. Therefore PAA solutions should never be distilled at atmospheric pressure. The distillation pressure should be maintained below 30 mmHg.

The boiling point at normal pressure is calculated as 110 °C.

Description of key information

Boiling point: 105 °C (100%, calculated)

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

105 °C

Additional information

Pure peracetic acid explodes when heated to about 100 to 110 °C. In addition, contact with metal ions or organic materials can cause explosions. However, Peracetic acid solution containing less than 45 % can be handled safely.

Commercial solutions have a boiling point of about 100 °C or slightly above which may be caused by the water content.

Based on modelling, the boiling point was estimated to be about 105 °C

Based on a weight of evidence approach and due to the fact that the boiling point cannot be determined directly the modelled boiling point of 105 °C is used as key value.