Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no. CAS Number International Chemical Identification
612-051-00-1 202-974-4 101-77-9 4,4'-diaminodiphenylmethane
4,4'-methylenedianiline

ATP Inserted / Updated: CLP00
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors, Acute Toxicity Estimates (ATE) Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 ** H370 **
STOT RE 2 * H373 ** H373 **
Aquatic Chronic 2 H411 H411

Signal Words Pictograms
Danger
GHS07
Exclamation mark
GHS08
Health hazard
GHS09
Environment
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Yes H3
E2
Notified classification and labelling
General Information
EC / List no.
Name CAS Number
202-974-4 4,4'-methylenedianiline 101-77-9

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

Additional Notified Information

Number of Notifiers

Joint Entries

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Acute Tox. 3 H301 H301 GHS07
GHS08
GHS09
GHS06
Dgr
M(Chronic)=10
M=1
State/Form
18 yes View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:liver, re...) H370
STOT RE 2 H373 (liver) H373
Aquatic Acute 1 H400 H400
Aquatic Chronic 1 H410 H410
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
M(Chronic)=0
State/Form
9 yes View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:liver, re...) H370
STOT RE 2 H373 (liver) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
State/Form
185 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 H370
STOT RE 2 H373 H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
State/Form
153 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:-) H370
STOT SE 1 H370 H370
STOT RE 2 H373 (other:-) H373
STOT RE 2 H373 H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
State/Form
87 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Liver, Eye (ret...) H370
STOT RE 2 H373 (Liver) H373
Aquatic Acute 1 H400 H400
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS08
GHS09
GHS06
Dgr
M=1
55 View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:-) H370
STOT RE 2 H373 (other:-) H373
Aquatic Acute 1 H400 H400
Aquatic Chronic 2 H411 H411
Acute Tox. 4 H302 H302 GHS07
GHS08
GHS09
Dgr
37 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (Not available) H370
STOT SE 1 H370 (other:Not avail...) H370
STOT RE 2 H373 (Not available) H373
STOT RE 2 H373 (other:Not avail...) H373
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS08
GHS09
GHS06
Dgr
M=1
M(Chronic)=10
31 View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341 (Suspected of ca...)
Carc. 1B H350 H350 (May cause cance...)
STOT SE 1 H370 (other:Liver) H370 (Causes damage t...)
STOT RE 2 H373 (other:Liver) H373 (May cause damag...)
Aquatic Acute 1 H400  
  H410
Aquatic Chronic 2 H411  
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
17 View details
Muta. 2 H341 H341
Carc. 1B H350  
STOT SE 1 H370 (not specified)  
STOT RE 2 H373 (not specified)  
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS08
GHS09
GHS06
Dgr
State/Form
16 View details
Skin Sens. 1 H317 H317
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (not specified)  
STOT RE 2 H373 (not specified)  
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
State/Form
14 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:unknown) H370
STOT RE 2 H373 (other:unknown) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
M(Chronic)=0
6 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (liver, retina) H370
STOT RE 2 H373 (liver) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 (H317) GHS07
GHS08
GHS09
Dgr
5 View details
Muta. 2 H341 H341 (H341)
Carc. 1B H350 H350 (H350)
STOT SE 1 H370 (other:eyes, liv...) H370 (H370)
STOT SE 1 H370 (eyes, liver, ca...) H370 (H370)
STOT RE 2 H373 (eyes, liver, ca...) H373 (H373)
STOT RE 2 H373 (other:eyes, liv...) H373 (H373)
Aquatic Chronic 2 H411 H411 (H411)
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
Note E
State/Form
3 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 H370
STOT RE 2 H373 H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
2 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:Several) H370
STOT SE 1 H370 (Several) H370
STOT RE 2 H373 (Several) H373
STOT RE 2 H373 (other:Several) H373
  H411
Skin Sens. 1 H317 H317 GHS08
GHS09
Dgr
State/Form
1 View details
Muta. 2 H341  
Carc. 1B H350 H350
STOT SE 1 H370 (Affected organ) H370
STOT SE 1 H370 (other:Affected ...) H370
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS08
GHS07
GHS09
Dgr
1 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (other:-) H370
STOT RE 2 H373 (other:-) H373
Aquatic Chronic 2 H411 H411
Skin Sens. 1 H317 H317 GHS07
GHS08
GHS09
Dgr
State/Form
1 View details
Muta. 2 H341 H341
Carc. 1B H350 H350
STOT SE 1 H370 (dermal,inhalati...) H370
STOT RE 2 H373 (dermal,inhalati...) H373
Aquatic Chronic 2 H411 H411

Number of Aggregated Notifications: 18