EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 19 April 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
calcium cyanamide
205-861-8
156-62-7
Acute Tox. 4; STOT SE 3; Eye Dam. 1
calcium octadecylxylenesulphonate
Z 7
402-040-8
148262-93-5
Skin Corr. 1B
calcium phosphide; tricalcium diphosphide
215-142-0
1305-99-3
Water-react. 1; Acute Tox. 2; Acute Tox. 3; Acute Tox. 1; Eye Dam. 1
calcium polysulphides
215-709-2
1344-81-6
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
captan (ISO);1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide
205-087-0
133-06-2
Carc. 2; Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
carbendazim (ISO);methyl benzimidazol-2-ylcarbamate
234-232-0
10605-21-7
Muta. 1B; Repr. 1B; Skin Sens. 1
carbetamide (ISO); (R)-1-(ethylcarbamoyl) ethyl carbanilate; (2R)-1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate
240-286-6
16118-49-3
Carc. 2; Repr. 1B; Acute Tox. 4
carbofuran (ISO); 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-methylcarbamate
216-353-0
1563-66-2
Acute Tox. 2
carbonic acid, nickel salt
240-408-8
16337-84-1
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
cartap hydrochloride
239-309-2
15263-52-2
Acute Tox. 4
chloralose (INN); (R)-1,2-O-(2,2,2-trichloroethylidene)-α-D-glucofuranose; glucochloralose; anhydroglucochloral
240-016-7
15879-93-3
Acute Tox. 4; Acute Tox. 3; STOT SE 3
chlordecone (ISO); perchloropentacyclo[5,3,0,02,6,03,9,0 4,8]decan-5-one; decachloropentacyclo[5,2,1,02,6,03,9,05,8]decan-4-one
205-601-3
143-50-0
Carc. 2; Acute Tox. 3
chlordimeform hydrochloride; N'-(4-chloro-o-tolyl)-N,N-dimethylformamidine monohydrochloride; N2-(4-chloro-o-tolyl)-N1,N1-dimethylformamidine hydorchloride
243-269-1
19750-95-9
Carc. 2; Acute Tox. 4
chlorfenapyr (ISO); 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile
602-782-4
122453-73-0
Acute Tox. 3; Acute Tox. 4
chlorfenprop-methyl; methyl 2-chloro-3-(4-chlorophenyl)propionate
238-413-5
14437-17-3
Acute Tox. 4
chloridazon (ISO); 5-amino-4-chloro-2-phenylpyridazine-3-(2H)-one; pyrazon
216-920-2
1698-60-8
Skin Sens. 1
chlorine dioxide;chlorine dioxide ... %
233-162-8
10049-04-4
Acute Tox. 3; Skin Corr. 1B
chlorine dioxide;chlorine dioxide ... %
233-162-8
10049-04-4
Press. Gas; Ox. Gas 1; Acute Tox. 2; Skin Corr. 1B
chlormethyl methyl ether; chlorodimethyl ether
203-480-1
107-30-2
Flam. Liq. 2; Carc. 1A; Acute Tox. 4
chloroacetaldehyde
203-472-8
107-20-0
Carc. 2; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B
chloroacetonitrile
203-467-0
107-14-2
Acute Tox. 3
chlorobenzene
203-628-5
108-90-7
Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
chloroprene (stabilised); 2-chlorobuta-1,3-diene (stabilised)
204-818-0
126-99-8
Flam. Liq. 2; Carc. 1B; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
chlorothalonil (ISO); tetrachloroisophthalonitrile
217-588-1
1897-45-6
Carc. 2; Acute Tox. 2; STOT SE 3; Eye Dam. 1; Skin Sens. 1
chlorotoluron (ISO); 3-(3-chloro-p-tolyl)-1,1-dimethylurea
239-592-2
15545-48-9
Carc. 2; Repr. 2
chloroxylenol
215-316-6
1321-23-9
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
chlorphonium chloride (ISO); tributyl (2,4-dichlorobenzyl) phosphonium chloride
204-105-4
115-78-6
Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
chlorpropham (ISO); isopropyl 3-chlorocarbanilate
202-925-7
101-21-3
Carc. 2; STOT RE 2
chlorthiamid (ISO); 2,6-dichloro (thiobenzamide)
217-637-7
1918-13-4
Acute Tox. 4
chromium (VI) trioxide
215-607-8
1333-82-0
Ox. Sol. 1; Carc. 1A; Muta. 1B; Repr. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1
chromyl dichloride; chromic oxychloride
239-056-8
14977-61-8
Ox. Liq. 1; Carc. 1B; Muta. 1B; Skin Corr. 1A; Skin Sens. 1
cinerin II; 3-(but-2-enyl)-2-methyl-4- oxocyclopent-2-enyl 2,2-dimethyl-3-(3-methoxy-2-methyl-3-oxoprop-1-enyl)cyclopropanecarboxylate
204-454-2
121-20-0
Acute Tox. 4
cinidon ethyl (ISO); ethyl (Z)-2-chloro-3-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboximido)phenyl]acrylate
604-318-6
142891-20-1
Carc. 2; Skin Sens. 1
cinnamaldehyde; 3-phenylprop-2-enal; cinnamic aldehyde; cinnamal
203-213-9
104-55-2
Skin Sens. 1A
cis-1,2,3,6-tetrahydro-4-methylphthalic anhydride
216-906-6
1694-82-2
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinamine
425-080-8
104860-26-6
Acute Tox. 4; STOT RE 2; Eye Dam. 1
cis-cyclohexane-1,2-dicarboxylicanhydride
236-086-3
13149-00-3
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-dichloroethylene
205-859-7
156-59-2
Flam. Liq. 2; Acute Tox. 4
citric acid, ammonium nickel salt
242-161-1
18283-82-4
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
clodinafop-propargyl (ISO)
600-662-6
105512-06-9
Acute Tox. 4; STOT RE 2; Skin Sens. 1
clopyralid (ISO); 3,6-dichloropyridine-2-carboxylic acid
216-935-4
1702-17-6
Eye Dam. 1
clorofene; chlorophene; 2-benzyl-4-chlorophenol
204-385-8
120-32-1
Carc. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1; Eye Dam. 1; STOT RE 2
cobalt dinitrate
233-402-1
10141-05-6
Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
cobalt lithium nickel oxide
442-750-5
113066-89-0
Carc. 1A; Acute Tox. 2; STOT RE 1; Skin Sens. 1
cobalt nickel oxide
620-395-9
12737-30-3
Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt oxide
215-154-6
1307-96-6
Acute Tox. 4; Skin Sens. 1
cobalt sulfate
233-334-2
10124-43-3
Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
cobalt sulfide
215-273-3
1317-42-6
Skin Sens. 1
copper(II) carbonate-copper(II) hydroxide (1:1)
235-113-6
12069-69-1
Acute Tox. 4; Eye Irrit. 2
coriandrol; (S)-3,7-dimethyl-1,6-octadien-3-ol; d-linalool
204-810-7
126-90-9
Skin Sens. 1B
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