EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

RELEVANT LEGISLATION
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esters of 2,4-D

EC / List no: - CAS no: -
EU CLP (1272/2008)
Acute Tox. 4; Skin Sens. 1

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Name EC / List no. CAS no. Association
Isobutyl 2,4-dichlorophenoxyacetate 216-992-5 1713-15-1 Expert judgement
Trimethylsilyl (2,4-dichlorophenoxy)acetate - 34113-76-3 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 4-chloro-2-butenyl ester - 2971-38-2 Expert judgement
1,3-dimethylbutyl 2-(2,4-dichlorophenoxy)acetate 300-531-0 93941-81-2 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, ester with 4-hydroxycoumarin - 7565-90-4 Expert judgement
2,4-D sec-butyl ester - 94-79-1 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-propenyl ester - 58965-05-2 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(1-oxopro-poxy)ethyl ester - 42313-94-0 Expert judgement
Pentyl (2,4-dichlorophenoxy)acetate 217-631-4 1917-92-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-[(pentyloxy)-methoxy]ethyl ester - 59577-71-8 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-chloro-4-nitrophenyl ester - 53640-16-7 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-hydroxyethyl ester - 38383-43-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, (3-nitro-4-(phenylsulfinyl)phenyl)methyl ester - 66711-18-0 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(butoxy-methoxy)ethyl ester - 59577-70-7 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-methoxy-cyclohexyl ester - 52176-65-5 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-[(hexyloxy)-methoxy]ethyl ester - 59577-72-9 Expert judgement
Isopropyl 2,4-dichlorophenoxyacetate 202-305-6 94-11-1 Expert judgement
Tetrahydrofurfuryl 2,4-dichlorophenoxyacetate 239-207-8 15146-99-3 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 4-pyridinyl ester, N-oxide - 54718-52-4 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-[(heptyloxy)-methyl]ethyl ester - 59577-74-1 Expert judgement
Acetic acid, (2,4-dichlorophenoxy-, 3-iodo-2-propynyl ester - 71983-94-3 Expert judgement
Heptyl 2,4-dichlorophenoxyacetate 217-634-0 1917-96-0 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-[(octyloxy)-methoxy]ethyl ester - 59577-73-0 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, vinyl ester - 4280-66-4 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2,3,3-trichloro-2-propenyl ester - 29670-84-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(dipropylamino)-1-methylethyl ester - 15887-75-9 Expert judgement
Isooctyl (2,4-dichlorophenoxy)acetate 246-704-3 25168-26-7 Expert judgement
2-butoxyethyl 2,4-dichlorophenoxyacetate 217-680-1 1929-73-3 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2,3-dihydroxypropyl ester - 28917-83-1 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 1,1-dimethyl-ethyl ester - 36304-26-4 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo- - 40797-15-7 Expert judgement
(2,4-Dichlorophenoxy)acetic acid 2-butoxy-2-oxoethyl ester - 52671-26-8 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 1-methyl-2,4-dioxo-3-phenyl-4-imidazolidinyl ester - 56402-60-9 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-[(2-chloroethoxy)methoxy]ethyl ester - 59577-75-2 Expert judgement
2-Butoxypropyl (2,4-dichlorophenoxy)acetate - 10463-14-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, dodecyl ester - 62855-71-4 Expert judgement
Butyl 2,4-dichlorophenoxyacetate 202-364-8 94-80-4 Expert judgement
2,4-D 3-butoxypropyl ester - 1928-45-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(propoxy-methoxy)ethyl ester - 59577-69-4 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 1,3-propane-diyl ester - 28188-32-1 Expert judgement
2,4-D, 2-octyl ester - 1917-97-1 Expert judgement
4-hydroxybutyl (2,4-dichlorophenoxy)acetate 252-929-8 36227-43-7 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, (2-chloroethyl)dimethylsilyl ester - 51663-83-3 Expert judgement
Ethyl 2,4-dichlorophenoxyacetate 208-558-9 533-23-3 Expert judgement
Propyl 2,4-dichlorophenoxyacetate 217-677-5 1928-61-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 4-chloro-2-nitrophenyl ester - 53640-15-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, [4-[(4-methylphenyl)sulfinyl]-3-nitrophenyl]methyl ester - 66711-19-1 Expert judgement
2-ethylhexyl 2,4-dichlorophenoxyacetate 217-673-3 1928-43-4 Expert judgement
Nitrilotri-2,1-ethanediyl tris[(2,4-dichlorophenoxy)acetate] 299-308-8 93858-74-3 Expert judgement
Methyl 2,4-dichlorophenoxyacetate 217-670-7 1928-38-7 Expert judgement
(2,4-Dichlorophenoxy)acetic acid, (4-hydroxy-3-nitrophenyl)methyl ester - 26351-71-3 Expert judgement
1-butoxypropan-2-yl 2-(2,4-dichlorophenoxy)acetate - 3966-11-8 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, tetrahydro-2-furanyl ester - 51822-88-9 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-fluoro-cyclohexyl ester - 52176-63-3 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, (2-bromoethyl)-dimethylsilyl ester - 51663-84-4 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, ethenyl ester, homopolymer - 55972-44-6 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 4-pentylphenyl ester - 53640-17-8 Expert judgement
Octyl (2,4-dichlorophenoxy)acetate 217-674-9 1928-44-5 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(acetyloxy)-ethyl ester - 42313-93-9 Expert judgement
Nonyl (2,4-dichlorophenoxy)acetate 259-722-1 55617-55-5 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-(ethoxy-methoxy)ethyl ester - 59577-68-3 Expert judgement
2,4-D crotyl ester - 14600-07-8 Expert judgement
Hexyl 2,4-dichlorophenoxyacetate 217-633-5 1917-95-9 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 3,3-difluoro-2-propenyl ester - 840-85-7 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, (4-((4-chlorophenyl)sulfinyl)-3-nitrophenyl)methyl ester - 66711-20-4 Expert judgement
2,4-Dichlorophenoxyacetic acid 2-dimethylaminoethyl ester hydrochloride - 64046-52-2 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, 2-butoxymethylethyl ester - 1320-18-9 Expert judgement
Acetic acid, (2,4-dichlorophenoxy)-, (pentafluorophenyl)methyl ester - 68704-50-7 Expert judgement