EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

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Last updated 22 October 2021. Database contains 4812 unique substances/entries.
Substance Name EC No. CAS No. EU CLP (1272/2008) EU_BA Directive 2000/54/EC EU REACH: List of SVHC
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Chloro-m-tolylmercury ecnumber: 227-722-0 | casnumber: 5955-19-1
Dipropyl mercury ecnumber: - | casnumber: 628-85-3
Bis[(trimethylsilyl)methyl]mercury ecnumber: 236-315-7 | casnumber: 13294-23-0
Mercury, chloro(4-((2,4-dinitrophenyl)amino)phenyl)- ecnumber: - | casnumber: 15785-93-0
Diisopropylmercury ecnumber: - | casnumber: 1071-39-2
Phenylmercury salicylate ecnumber: 248-828-3 | casnumber: 28086-13-7
6-methyl-3-nitrobenzoxamercurete ecnumber: 205-112-5 | casnumber: 133-58-4
Phenylmercury hydroxide ecnumber: 202-866-7 | casnumber: 100-57-2
(acetato-O)methylmercury ecnumber: 203-547-5 | casnumber: 108-07-6
Chloro(trans-2-methoxycyclooctyl)mercury ecnumber: - | casnumber: 5185-84-2
Mercury(2+) (9Z,12Z)-octadeca-9,12-dienoate ecnumber: 231-814-6 | casnumber: 7756-49-2
Bromomethylmercury ecnumber: 208-057-5 | casnumber: 506-83-2
4-(Chloromercuri)benzenesulfonic acid monosodium salt ecnumber: 683-356-5 | casnumber: 14110-97-5
Diiodo(5-iodopyridin-2-amine-N1)mercury ecnumber: 298-602-3 | casnumber: 93820-20-3
2-methoxyethylmercury acetate ecnumber: 205-790-2 | casnumber: 151-38-2
[2,2',2''-nitrilotri(ethanol)-N,O,O',O'']phenylmercury lactate ecnumber: 245-581-3 | casnumber: 23319-66-6
Mercury(1+) ethyl sulphate ecnumber: 275-904-3 | casnumber: 71720-55-3
Hydrargaphen ecnumber: 238-107-1 | casnumber: 14235-86-0
(neodecanoato-O)phenylmercury ecnumber: 247-783-7 | casnumber: 26545-49-3
Mercury, iodo(trifluoromethyl)- ecnumber: - | casnumber: 421-11-4
Phenyl(trichloromethyl)mercury ecnumber: 221-960-9 | casnumber: 3294-57-3
[2-ethylhexyl hydrogen maleato-O']phenylmercury ecnumber: 248-559-1 | casnumber: 27605-30-7
(2-carboxyphenyl)hydroxymercury ecnumber: 237-918-8 | casnumber: 14066-61-6
4-aminophenylmercury acetate ecnumber: 228-497-1 | casnumber: 6283-24-5
Meralein sodium ecnumber: 224-498-6 | casnumber: 4386-35-0
Hydrogen [metasilicato(2-)-O](2-methoxyethyl)mercurate(1-) ecnumber: 264-920-6 | casnumber: 64491-92-5
Mercury(1+) trifluoroacetate ecnumber: 220-875-4 | casnumber: 2923-15-1
Disodium tetra(cyano-C)mercurate(2-) ecnumber: 239-766-8 | casnumber: 15682-88-9
[μ-[(oxydiethylene but-2-enedioato)(2-)]]diphenyldimercury ecnumber: 301-791-8 | casnumber: 94070-92-5
4-Chloromercuriphenol ecnumber: - | casnumber: 623-07-4
Bis(ethylthio)mercury ecnumber: - | casnumber: 811-50-7
[naphthoato(1-)-O]phenylmercury ecnumber: 250-736-3 | casnumber: 31632-68-5
Bromophenylmercury ecnumber: 214-760-8 | casnumber: 1192-89-8
Phenylmercury acetate ecnumber: 200-532-5 | casnumber: 62-38-4
2-Chloromercuri-4-nitrophenol ecnumber: - | casnumber: 24579-90-6
Sodium 4-chloromercuriobenzoate ecnumber: 221-700-4 | casnumber: 3198-04-7
Amminephenylmercury(1+) acetate ecnumber: 245-006-6 | casnumber: 22450-90-4
Chlormerodrin ecnumber: 200-530-4 | casnumber: 62-37-3
N-(ethylmercurio)toluene-4-sulphonanilide ecnumber: 208-231-0 | casnumber: 517-16-8
Mersalyl ecnumber: 207-748-9 | casnumber: 492-18-2
Phenylmercuric phthalate ecnumber: 664-337-0 | casnumber: 84-70-8
2-(ethylmercuriothio)benzoic acid ecnumber: 205-719-5 | casnumber: 148-61-8
BMC ecnumber: 663-974-1 | casnumber: 543-63-5
Mercury, (acetato)pyridyl- (8CI) ecnumber: - | casnumber: 1334-77-6
Chloro[p-[(2-hydroxy-1-naphthyl)azo]phenyl]mercury ecnumber: 221-358-6 | casnumber: 3076-91-3
Bis(5-oxo-DL-prolinato-N1,O2)mercury ecnumber: 304-523-8 | casnumber: 94276-38-7
1H-Tetrazole, 5-nitro-, mercury(2+) salt ecnumber: - | casnumber: 60345-95-1
Dimethylmercury ecnumber: 209-805-3 | casnumber: 593-74-8
Mercury(2+) tetrakis(thiocyanato-N)cobaltate(2-) ecnumber: 248-602-4 | casnumber: 27685-51-4
(phenylmercurio)urea ecnumber: 218-909-8 | casnumber: 2279-64-3
Hydrogen μ-hydroxy[μ-[orthoborato(3-)-O:O']]diphenyldimercurate(1-) ecnumber: 304-637-8 | casnumber: 94277-53-9
Phenylmercury chloride ecnumber: 202-865-1 | casnumber: 100-56-1
(dihydroxyphenyl)phenylmercury ecnumber: 248-426-8 | casnumber: 27360-58-3
Di-sec-butylmercury ecnumber: - | casnumber: 691-88-3
Diphenyl[μ-[(tetrapropenyl)succinato(2-)-O:O']]dimercury ecnumber: 248-355-2 | casnumber: 27236-65-3
Mercury acetate ecnumber: 209-766-2 | casnumber: 592-63-2
2-Acetoxymercurio-4-nitrophenol ecnumber: - | casnumber: 63468-53-1
Bis(5-oxo-L-prolinato-N1,O2)mercury ecnumber: 305-388-8 | casnumber: 94481-62-6
[μ-[orthoborato(2-)-O:O']]diphenyldimercury ecnumber: 228-465-7 | casnumber: 6273-99-0
Mercury dibenzoate ecnumber: 209-499-1 | casnumber: 583-15-3
Methylmercury hydroxide ecnumber: 214-667-2 | casnumber: 1184-57-2
(acetato-O)ethylmercury ecnumber: 203-688-2 | casnumber: 109-62-6
Phenylmercury stearate ecnumber: 203-217-0 | casnumber: 104-59-6
(bromodichloromethyl)phenylmercury ecnumber: 221-961-4 | casnumber: 3294-58-4
(acetato-O)[3-(chloromethoxy)propyl-C,O]mercury ecnumber: 227-719-4 | casnumber: 5954-14-3
Sodium 4-hydroxymercuriobenzoate ecnumber: 205-340-5 | casnumber: 138-85-2
Mercury, (acetato-O)(methylphenyl)- ecnumber: - | casnumber: 1300-78-3
Mercury distearate ecnumber: 211-458-8 | casnumber: 645-99-8
Mercuderamide ecnumber: 208-371-2 | casnumber: 525-30-4
Di(acetato-O)anilinemercury ecnumber: 264-306-8 | casnumber: 63549-47-3
Methylmercury benzoate ecnumber: 222-834-6 | casnumber: 3626-13-9
Mercury, (nitrate-O)(trifluoromethyl)- ecnumber: - | casnumber: 461-40-5
Dimethyl[μ-[sulphato(2-)-O:O']]dimercury ecnumber: 223-288-1 | casnumber: 3810-81-9
Bis(lactato-O1,O2)mercury ecnumber: 242-667-2 | casnumber: 18917-83-4
3-(Acetoxymercuri)pyridine ecnumber: - | casnumber: 102-99-8
Ethyliodomercury ecnumber: 219-471-0 | casnumber: 2440-42-8
2-methoxyethylmercury chloride ecnumber: 204-659-7 | casnumber: 123-88-6
Mercaptomerin sodium ecnumber: 244-298-2 | casnumber: 21259-76-7
Disuccinimidomercury ecnumber: 209-537-7 | casnumber: 584-43-0
Phenylmercury propionate ecnumber: 203-094-3 | casnumber: 103-27-5
4-Chloromercuribenzenesulfonate ecnumber: - | casnumber: 554-77-8
(metaborato-O)phenylmercury ecnumber: 250-518-8 | casnumber: 31224-71-2
Mercurobutol ecnumber: 207-869-7 | casnumber: 498-73-7
1-cyano-3-(methylmercurio)guanidine ecnumber: 207-935-5 | casnumber: 502-39-6
Mercury difulminate ecnumber: 211-057-8 | casnumber: 628-86-4
Ethylmercury chloride ecnumber: 203-478-0 | casnumber: 107-27-7
basic phenylmercury nitrate ecnumber: 620-403-0 | casnumber: 8003-05-2
Naphthenic acids, mercury salts ecnumber: 215-651-8 | casnumber: 1336-96-5
[salicylato(2-)-O1,O2]mercury ecnumber: 227-760-8 | casnumber: 5970-32-1
(oleato)phenylmercury ecnumber: 203-218-6 | casnumber: 104-60-9
Hydroxymercury nitrile ecnumber: - | casnumber: 31065-88-0
Lactic acid, mercury(2+) salt (2:1) (8CI) ecnumber: - | casnumber: 814-82-4
[benzoato(2-)-C2,O1]mercury ecnumber: 227-228-5 | casnumber: 5722-59-8
Phenylmercury benzoate ecnumber: 202-331-8 | casnumber: 94-43-9
Bis(trichloromethyl)mercury ecnumber: 229-867-5 | casnumber: 6795-81-9
Dimercury di(acetate) ecnumber: 211-161-3 | casnumber: 631-60-7
2-ethoxyethylmercury acetate ecnumber: 204-678-0 | casnumber: 124-08-3
Chloro-o-tolylmercury ecnumber: 220-469-7 | casnumber: 2777-37-9
Amylmercury chloride ecnumber: - | casnumber: 544-15-0
Phenylmercury dimethyldithiocarbamate ecnumber: 251-026-6 | casnumber: 32407-99-1
Mersalyl acid ecnumber: 207-637-5 | casnumber: 486-67-9
Mercury di(acetate) ecnumber: 216-491-1 | casnumber: 1600-27-7
Iodomethylmercury ecnumber: 205-600-8 | casnumber: 143-36-2
Mercury, diheptyl- ecnumber: - | casnumber: 51622-02-7
Mercury succinate ecnumber: 209-656-4 | casnumber: 589-65-1
Mercury bis(4-chlorobenzoate) ecnumber: 239-548-2 | casnumber: 15516-76-4
2-ethoxyethylmercury chloride ecnumber: 204-670-7 | casnumber: 124-01-6
Phenyl(tribromomethyl)mercury ecnumber: 221-963-5 | casnumber: 3294-60-8
Chipcote ecnumber: - | casnumber: 2597-97-9
4-hydroxymercuric?phenyl sulfonic acid, sodium salt ecnumber: - | casnumber: 73548-15-9
Chloromercuriferrocene ecnumber: 631-381-7 | casnumber: 1273-75-2
Otimerate sodium ecnumber: 240-572-0 | casnumber: 16509-11-8
Di(phenylmercury) dodecylsuccinate ecnumber: - | casnumber: 24806-32-4
Mercurous gluconate ecnumber: - | casnumber: 63937-14-4
Mercurate(1-), [dodecenylbutanedioato(2-)-O']phenyl-, hydrogen ecnumber: 304-575-1 | casnumber: 94276-88-7
Sodium timerfonate ecnumber: 227-741-4 | casnumber: 5964-24-9
Bromoethylmercury ecnumber: 203-477-5 | casnumber: 107-26-6
(2-ethylhexanoato)phenylmercury ecnumber: 236-326-7 | casnumber: 13302-00-6
Phenylmercury nitrate ecnumber: 200-242-9 | casnumber: 55-68-5
Mercury, chloropyridinyl- ecnumber: - | casnumber: 1334-75-4
Mercury bis(2-ethylhexanoate) ecnumber: 236-113-9 | casnumber: 13170-76-8
2-chloromercuriophenol ecnumber: 201-962-6 | casnumber: 90-03-9
2-hydroxy-5-(1,1,3,3-tetramethylbutyl)phenylmercury acetate ecnumber: 209-534-0 | casnumber: 584-18-9
Mercury, (pentachlorophenoxy)phenyl- ecnumber: - | casnumber: 1142-64-9
[(2-hydroxyethyl)amino]phenylmercury acetate ecnumber: 263-211-9 | casnumber: 61792-06-1
Tris(ethylmercury) phosphate ecnumber: 218-790-2 | casnumber: 2235-25-8
Diethylmercury ecnumber: 211-000-7 | casnumber: 627-44-1
[μ-[(oxydiethylene phthalato)(2-)]]diphenylmercury ecnumber: 301-792-3 | casnumber: 94070-93-6
Methyl(pentachlorophenolato)mercury ecnumber: 227-596-7 | casnumber: 5902-76-1
Mercury hydrogen cyclohexanebutyrate ecnumber: 263-665-8 | casnumber: 62638-02-2
Merbromin ecnumber: 204-933-6 | casnumber: 129-16-8
Mercury bis(trifluoroacetate) ecnumber: 236-250-4 | casnumber: 13257-51-7
Mercury, bis(3-fluorophenyl)- ecnumber: - | casnumber: 1961-02-0
Iodo(iodomethyl)mercury ecnumber: 205-485-4 | casnumber: 141-51-5
Di-p-tolylmercury ecnumber: 208-672-9 | casnumber: 537-64-4
Mercurate(2-), tetraiodo-, copper(2+) (1:1), (T-4)- ecnumber: - | casnumber: 27228-67-7
mercury, chloro(3-hydroxyphenyl)- ecnumber: - | casnumber: 70538-27-1
p-tolylmercury chloride ecnumber: 208-716-7 | casnumber: 539-43-5
Dihydrogen [orthoborato(3-)-O]phenylmercurate(2-) ecnumber: 203-068-1 | casnumber: 102-98-7
(lactato-O1,O2)mercury ecnumber: 242-673-5 | casnumber: 18918-06-4
Mercury dithizonate ecnumber: 621-496-0 | casnumber: 14783-59-6
Octadecanoic acid, mercury(1+) salt ecnumber: - | casnumber: 86320-46-9
Diiodobis(5-iodopyridin-2-amine)mercury dihydroiodide ecnumber: 264-100-8 | casnumber: 63325-16-6
(Pentafluorophenyl)mercury ecnumber: - | casnumber: 973-17-1
Diphenylmercury ecnumber: 209-606-1 | casnumber: 587-85-9
Chloromethylmercury ecnumber: 204-064-2 | casnumber: 115-09-3
Thiomersal ecnumber: 200-210-4 | casnumber: 54-64-8
Phenyl(quinolin-8-olato-N1,O8)mercury ecnumber: 238-316-8 | casnumber: 14354-56-4
Chloro(hydroxyphenyl)mercury ecnumber: 215-308-2 | casnumber: 1320-80-5
Mercury dioleate ecnumber: 214-741-4 | casnumber: 1191-80-6
Dibutylrtut ecnumber: - | casnumber: 629-35-6
methylmercury salts ecnumber: 694-823-8 | casnumber: 22967-92-6
(2-carboxy-m-tolyl)hydroxymercury, monosodium salt ecnumber: 258-195-5 | casnumber: 52795-88-7
Mercury, bis(phenylmethyl)- ecnumber: 677-698-4 | casnumber: 780-24-5
Ethanethiolmercury chloride ecnumber: - | casnumber: 1785-43-9
[μ-[metasilicato(2-)-O:O]]bis(2-methoxyethyl)dimercury ecnumber: 242-997-7 | casnumber: 19367-79-4
4-chloromercuriobenzoic acid ecnumber: 200-442-6 | casnumber: 59-85-8
Lactatophenylmercury ecnumber: 204-560-9 | casnumber: 122-64-5
Bis[(+)-lactato]mercury ecnumber: 251-657-7 | casnumber: 33724-17-3
Chloropropylmercury ecnumber: - | casnumber: 2440-40-6
Chloro-2-thienylmercury ecnumber: 227-481-1 | casnumber: 5857-39-6
(Trifluoromethyl)mercuric bromide ecnumber: - | casnumber: 421-09-0
Bromo(2-hydroxypropyl)mercury ecnumber: 242-613-8 | casnumber: 18832-83-2
Bis(ethylmercuri)phosphate ecnumber: - | casnumber: 2440-45-1
(4-((4-(Dimethylamino)phenyl)azo)phenyl)mercuric acetate ecnumber: 631-561-5 | casnumber: 19447-62-2
Di-o-tolylmercury ecnumber: 210-499-9 | casnumber: 616-99-9
Mercury, hydroxy(hydroxynitrophenyl)-, monosodium salt ecnumber: - | casnumber: 1300-34-1
Ethylhydroxymercury ecnumber: - | casnumber: 107-28-8
(maleoyldioxy)bis[phenylmercury] ecnumber: 220-286-2 | casnumber: 2701-61-3
Mercury, iodophenyl- ecnumber: 664-429-0 | casnumber: 823-04-1
2-Chloro-4-(hydroxymercuriphenol) ecnumber: - | casnumber: 538-04-5
(acetato-O)diamminephenylmercury ecnumber: 269-247-1 | casnumber: 68201-97-8
Mercury(2+) chloroacetate ecnumber: 247-925-8 | casnumber: 26719-07-3
Dipotassium tetracyanomercurate ecnumber: 209-735-3 | casnumber: 591-89-9
Trimercury biscitrate ecnumber: 242-096-9 | casnumber: 18211-85-3
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Acute Tox. 2; Acute Tox. 1; STOT RE 2

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