Candidate List of substances of very high concern for Authorisation

Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

  • Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
  • Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
  • Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry. 
Filter the list
Date of inclusion:

The List does not contain any Substances.
Decision IUCLID dataset  
271-093-5
68515-50-4
16-Jun-2014
Toxic for reproduction (Article 57c)
Details
271-084-6
68515-42-4
20-Jun-2011
Toxic for reproduction (Article 57c)
Details
276-158-1
71888-89-6
20-Jun-2011
Toxic for reproduction (Article 57c)
Details
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)
show/hide
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters EC No.: 271-094-0 | CAS No.: 68515-51-5
-
-
15-Jun-2015
Toxic for reproduction (Article 57c)


Details
202-486-1
96-18-4
20-Jun-2011
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
203-794-9
110-71-4
18-Jun-2012
Toxic for reproduction (Article 57c)
Details
215-147-8
1306-23-6
16-Dec-2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
show/hide
Monteponite (CdO) EC No.: - | CAS No.: 12139-21-8
215-146-2
1306-19-0
20-Jun-2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
233-710-6
10325-94-7
15-Jan-2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
244-168-5
21041-95-2
15-Jan-2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
208-168-9
513-78-0
15-Jan-2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
231-152-8
7440-43-9
20-Jun-2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
including cis- and trans- stereo isomeric forms and all possible combinations of the isomers
show/hide
Hexahydro-1-methylphthalic anhydride EC No.: 256-356-4 | CAS No.: 48122-14-1
Hexahydro-3-methylphthalic anhydride EC No.: 260-566-1 | CAS No.: 57110-29-9
Hexahydromethylphthalic anhydride EC No.: 247-094-1 | CAS No.: 25550-51-0
Hexahydro-4-methylphthalic anhydride EC No.: 243-072-0 | CAS No.: 19438-60-9
-
-
19-Dec-2012
Respiratory sensitising properties (Article 57(f) - human health)




Details
203-856-5
111-30-8
08-Jul-2021
Respiratory sensitising properties (Article 57(f) - human health)
Details
EDA
203-468-6
107-15-3
27-Jun-2018
Respiratory sensitising properties (Article 57(f) - human health)
Details
204-650-8
123-77-3
19-Dec-2012
Respiratory sensitising properties (Article 57(f) - human health)
Details
all possible combinations of the cis- and trans-isomers
show/hide
trans-cyclohexane-1,2-dicarboxylic anhydride EC No.: 238-009-9 | CAS No.: 14166-21-3
Cyclohexane-1,2-dicarboxylic anhydride EC No.: 201-604-9 | CAS No.: 85-42-7
cis-cyclohexane-1,2-dicarboxylic anhydride EC No.: 236-086-3 | CAS No.: 13149-00-3
-
-
19-Dec-2012
Respiratory sensitising properties (Article 57(f) - human health)



Details
trimellitic anhydride; TMA
209-008-0
552-30-7
27-Jun-2018
Respiratory sensitising properties (Article 57(f) - human health)
Details
X4261
401-850-9
255881-94-8
17-Jan-2022
PBT (Article 57d)
Details
and all major diastereoisomers identified
show/hide
1,2,5,6,9,10-hexabromocyclododecane EC No.: 221-695-9 | CAS No.: 3194-55-6
gamma-hexabromocyclododecane EC No.: - | CAS No.: 134237-52-8
Hexabromocyclododecane EC No.: 247-148-4 | CAS No.: 25637-99-4
alpha-hexabromocyclododecane EC No.: - | CAS No.: 134237-50-6
beta-hexabromocyclododecane EC No.: - | CAS No.: 134237-51-7
-
-
28-Oct-2008
PBT (Article 57d)





Details
200-268-0
56-35-9
28-Oct-2008
PBT (Article 57d)
Details
204-371-1
120-12-7
28-Oct-2008
PBT (Article 57d)
Details
232-140-5
7789-00-6
18-Jun-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
213-103-2
924-42-5
10-Jun-2022
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
200-879-2
75-56-9
19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
200-589-6
64-67-5
19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
215-607-8
1333-82-0
15-Dec-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
201-173-7
79-06-1
30-Mar-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
show/hide
4,4'-oxydianiline EC No.: 202-977-0 | CAS No.: 101-80-4
-
-
19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
-
423-400-0
59653-74-6
18-Jun-2012
Mutagenic (Article 57b)
Details
219-514-3
2451-62-9
18-Jun-2012
Mutagenic (Article 57b)
Details
show/hide
Potassium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate EC No.: 249-616-3 | CAS No.: 29420-49-3
Ammonium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate EC No.: 269-513-7 | CAS No.: 68259-10-9
magnesium perfluorobutanesulfonate EC No.: - | CAS No.: 507453-86-3
lithium perfluorobutanesulfonate EC No.: - | CAS No.: 131651-65-5
morpholinium perfluorobutanesulfonate EC No.: - | CAS No.: 503155-89-3
1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid EC No.: 206-793-1 | CAS No.: 375-73-5
tetrabutyl-phosphonium nonafluoro-butane-1-sulfonate EC No.: 444-440-5 | CAS No.: 220689-12-3
dimethyl(phenyl)sulfanium perfluorobutanesulfonate EC No.: 452-310-4 | CAS No.: 220133-51-7
Triphenylsulfanium perfluorobutane sulfonate EC No.: 478-340-8 | CAS No.: 144317-44-2
bis(4-t-butylphenyl)iodonium perfluorobutanesulfonate EC No.: 432-660-4 | CAS No.: 194999-85-4
-
-
16-Jan-2020
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Details
203-615-4
108-78-1
17-Jan-2023
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Details
covering any of their individual isomers and combinations thereof
-
-
16-Jul-2019
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Details
204-661-8
123-91-1
08-Jul-2021
Carcinogenic (Article 57a)
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Details
224-208-8
4247-02-3
17-Jan-2023
Endocrine disrupting properties (Article 57(f) - human health)
Details
202-318-7
94-26-8
25-Jun-2020
Endocrine disrupting properties (Article 57(f) - human health)
Details
201-025-1
77-40-7
08-Jul-2021
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
-
-
17-Jan-2022
Endocrine disrupting properties (Article 57(f) - human health)
Details
show/hide
Phenol, 4-nonyl-, phosphite (3:1) EC No.: - | CAS No.: 3050-88-2
tris(nonylphenyl) phosphite EC No.: 247-759-6 | CAS No.: 26523-78-4
Phenol, p-isononyl-, phosphite (3:1) EC No.: - | CAS No.: 31631-13-7
Phenol, p-sec-nonyl-, phosphite EC No.: - | CAS No.: 106599-06-8
-
-
16-Jul-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)
-
-
15-Jan-2018
Endocrine disrupting properties (Article 57(f) - environment)
Details
201-280-9
80-46-6
12-Jan-2017
Endocrine disrupting properties (Article 57(f) - environment)
Details
202-679-0
98-54-4
16-Jul-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof
show/hide
2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol EC No.: 230-770-5 | CAS No.: 7311-27-5
20-(4-nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 248-743-1 | CAS No.: 27942-27-4
2-[2-(4-nonylphenoxy)ethoxy]ethanol EC No.: 243-816-4 | CAS No.: 20427-84-3
Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-209-1 | CAS No.: 68412-54-4
Nonylphenol, ethoxylated EC No.: 500-024-6 | CAS No.: 9016-45-9
4-Nonylphenol, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-045-0 | CAS No.: 26027-38-3
Nonylphenol, ethoxylated (15-EO) EC No.: - | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (10-EO) EC No.: - | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (8-EO) EC No.: - | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (6,5-EO) EC No.: - | CAS No.: 9016-45-9
2-(nonylphenoxy)ethanol EC No.: 248-762-5 | CAS No.: 27986-36-3
2-(isononylphenoxy)ethanol EC No.: 284-987-5 | CAS No.: 85005-55-6
20-(isononylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 265-785-6 | CAS No.: 65455-69-8
4-Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-315-8 | CAS No.: 127087-87-0
Isononylphenol, ethoxylated EC No.: - | CAS No.: 37205-87-1
4-Nonylphenol, branched, ethoxylated EC No.: - | CAS No.: 127087-87-0
4-t-Nonylphenol-diethoxylate EC No.: - | CAS No.: 156609-10-8
2-(4-nonylphenoxy)ethanol EC No.: - | CAS No.: 104-35-8
29-(nonylphenoxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosanol EC No.: 248-294-1 | CAS No.: 27177-08-8
23-(nonylphenoxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol EC No.: 248-293-6 | CAS No.: 27177-05-5
20-(nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 248-292-0 | CAS No.: 27177-03-3
2-[2-(nonylphenoxy)ethoxy]ethanol EC No.: 248-291-5 | CAS No.: 27176-93-8
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol EC No.: 247-816-5 | CAS No.: 26571-11-9
14-(nonylphenoxy)-3,6,9,12-tetraoxatetradecan-1-ol EC No.: 247-555-7 | CAS No.: 26264-02-8
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol; EC No.: 255-695-5 | CAS No.: 42173-90-0
Nonylphenol, ethoxylated (EO = 10) EC No.: - | CAS No.: -
Nonylphenol, ethoxylated (EO = 4) EC No.: - | CAS No.: -
Nonylphenol, ethoxylated (polymer) EC No.: - | CAS No.: -
2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethanol EC No.: - | CAS No.: 1119449-37-4
Nonylphenolpolyglycolether EC No.: - | CAS No.: -
799-990-1
-
20-Jun-2013
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
show/hide
p-(1,1-dimethylheptyl)phenol EC No.: 250-339-5 | CAS No.: 30784-30-6
4-(1-Ethyl-1,4-dimethylpentyl)phenol EC No.: - | CAS No.: 142731-63-3
4-(1-Ethyl-1,3-dimethylpentyl)phenol EC No.: - | CAS No.: 186825-36-5
Phenol, 4-nonyl-, branched EC No.: 284-325-5 | CAS No.: 84852-15-3
p-nonylphenol EC No.: 203-199-4 | CAS No.: 104-40-5
p-(1-methyloctyl)phenol EC No.: 241-427-4 | CAS No.: 17404-66-9
4-(1-ethyl-1-methylhexyl)phenol EC No.: 257-907-1 | CAS No.: 52427-13-1
p-isononylphenol EC No.: 247-770-6 | CAS No.: 26543-97-5
4-(1,1,5-Trimethylhexyl)phenol EC No.: - | CAS No.: 521947-27-3
Nonylphenol EC No.: 246-672-0 | CAS No.: 25154-52-3
Phenol, nonyl-, branched EC No.: 291-844-0 | CAS No.: 90481-04-2
4-(3-ethylheptan-2-yl)phenol EC No.: - | CAS No.: 186825-39-8
Isononylphenol EC No.: 234-284-4 | CAS No.: 11066-49-2
-
-
19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
show/hide
Phenol, heptyl derivs. EC No.: 276-743-1 | CAS No.: 72624-02-3
4-heptylphenol EC No.: 217-862-0 | CAS No.: 1987-50-4
4-(2,3,3-trimethylbutan-2-yl)phenol EC No.: - | CAS No.: 72861-06-4
4-(2,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 33104-11-9
4-(3-ethylpentan-3-yl)phenol EC No.: - | CAS No.: 37872-24-5
4-(2-methylhexan-2-yl)phenol EC No.: - | CAS No.: 30784-31-7
4-(3,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-06-7
4-(3-methylhexan-2-yl)phenol EC No.: - | CAS No.: 854904-93-1
4-(4,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-07-8
4-(4-methylhexan-2-yl)phenol EC No.: - | CAS No.: 71945-81-8
4-(3-methylhexan-3-yl)phenol EC No.: - | CAS No.: 30784-32-8
4-(2,2-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 861010-65-3
4-(5-methylhexan-3-yl)phenol EC No.: - | CAS No.: 854904-92-0
4-(heptan-3-yl)phenol EC No.: - | CAS No.: 6465-74-3
4-(heptan-2-yl)phenol EC No.: - | CAS No.: 6863-24-7
4-(heptan-4-yl)phenol EC No.: - | CAS No.: 6465-71-0
4-(3-ethylpentyl)phenol EC No.: - | CAS No.: 911370-98-4
4-(3-methylhexyl)phenol EC No.: - | CAS No.: 102570-52-5
4-(4-methylhexyl)phenol EC No.: - | CAS No.: 1139800-98-8
4-(5-methylhexyl)phenol EC No.: - | CAS No.: 100532-36-3
4-(2,4-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 1824346-00-0
4-(2,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 861011-60-1
Phenol, 4-(1-ethyl-1,2-dimethylpropyl)- EC No.: - | CAS No.: 30784-27-1
Phenol, 4-tert-heptyl- EC No.: - | CAS No.: 288864-02-8
4-(5-methylhexan-2-yl)phenol EC No.: - | CAS No.: 857629-71-1
-
-
12-Jan-2017
Endocrine disrupting properties (Article 57(f) - environment)
Details
covering well-defined substances and UVCB substances, polymers and homologues
-
-
19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
Details
205-426-2
140-66-9
19-Dec-2011
Endocrine disrupting properties (Article 57(f) - environment)
Details
3-benzylidene camphor; 3-BC
239-139-9
15087-24-8
15-Jan-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)
229-851-8
6786-83-0
18-Jun-2012
Carcinogenic (Article 57a)
Details

Export search results to: