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Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

  • Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
  • Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
  • Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry. 
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Date of inclusion:

Decision IUCLID dataset  
232-222-0
7790-79-6
17/12/2014
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
233-296-7
10108-64-2
16/06/2014
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
EC No. 233-139-2 and EC No. 234-343-4
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Boric acid, crude natural EC No.: 234-343-4 | CAS No.: 11113-50-1
Boric acid EC No.: 233-139-2 | CAS No.: 10043-35-3
-
-
18/06/2010
Toxic for reproduction (Article 57c)


Details
204-212-6
117-82-8
19/12/2011
Toxic for reproduction (Article 57c)
Details
203-924-4
111-96-6
19/12/2011
Toxic for reproduction (Article 57c)
Details
204-211-0
117-81-7
28/10/2008
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
201-622-7
85-68-7
28/10/2008
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - human health)
Details
223-320-4
3825-26-1
20/06/2013
Toxic for reproduction (Article 57c)
PBT (Article 57d)
Details
232-143-1
7789-09-5
18/06/2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Details
257-175-3
51404-69-4
19/12/2012
Toxic for reproduction (Article 57c)
Details
273-688-5
69011-06-9
19/12/2012
Toxic for reproduction (Article 57c)
Details
Bisphenol A; BPA
201-245-8
80-05-7
12/01/2017
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
421-150-7
143860-04-2
19/12/2012
Toxic for reproduction (Article 57c)
Details
400-600-6
71868-10-5
16/01/2020
Toxic for reproduction (Article 57c)
Details
203-772-9
110-49-6
16/07/2019
Toxic for reproduction (Article 57c)
Details
203-713-7
109-86-4
15/12/2010
Toxic for reproduction (Article 57c)
Details
239-622-4
15571-58-1
17/12/2014
Toxic for reproduction (Article 57c)
Details
203-839-2
111-15-9
20/06/2011
Toxic for reproduction (Article 57c)
Details
203-804-1
110-80-5
15/12/2010
Toxic for reproduction (Article 57c)
Details
404-360-3
119313-12-1
16/01/2020
Toxic for reproduction (Article 57c)
Details
401-720-1
6807-17-6
15/01/2019
Toxic for reproduction (Article 57c)
Details
212-828-1
872-50-4
20/06/2011
Toxic for reproduction (Article 57c)
Details
203-445-0
106-94-5
19/12/2012
Toxic for reproduction (Article 57c)
Details
211-076-1
629-14-1
19/12/2012
Toxic for reproduction (Article 57c)
Details
203-977-3
112-49-2
18/06/2012
Toxic for reproduction (Article 57c)
Details
284-032-2
84777-06-0
19/12/2012
Toxic for reproduction (Article 57c)
Details
271-093-5
68515-50-4
16/06/2014
Toxic for reproduction (Article 57c)
Details
271-084-6
68515-42-4
20/06/2011
Toxic for reproduction (Article 57c)
Details
276-158-1
71888-89-6
20/06/2011
Toxic for reproduction (Article 57c)
Details
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)
show/hide
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters EC No.: 271-094-0 | CAS No.: 68515-51-5
-
-
15/06/2015
Toxic for reproduction (Article 57c)
Details
202-486-1
96-18-4
20/06/2011
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
203-794-9
110-71-4
18/06/2012
Toxic for reproduction (Article 57c)
Details
215-147-8
1306-23-6
16/12/2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
215-146-2
1306-19-0
20/06/2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
233-710-6
10325-94-7
15/01/2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
244-168-5
21041-95-2
15/01/2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
208-168-9
513-78-0
15/01/2018
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
231-152-8
7440-43-9
20/06/2013
Carcinogenic (Article 57a)
Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
including cis- and trans- stereo isomeric forms and all possible combinations of the isomers
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Hexahydro-4-methylphthalic anhydride EC No.: 243-072-0 | CAS No.: 19438-60-9
Hexahydro-3-methylphthalic anhydride EC No.: 260-566-1 | CAS No.: 57110-29-9
Hexahydro-1-methylphthalic anhydride EC No.: 256-356-4 | CAS No.: 48122-14-1
Hexahydromethylphthalic anhydride EC No.: 247-094-1 | CAS No.: 25550-51-0
-
-
19/12/2012
Respiratory sensitising properties (Article 57(f) - human health)




Details
EDA
203-468-6
107-15-3
27/06/2018
Respiratory sensitising properties (Article 57(f) - human health)
Details
204-650-8
123-77-3
19/12/2012
Respiratory sensitising properties (Article 57(f) - human health)
Details
all possible combinations of the cis- and trans-isomers
show/hide
cis-cyclohexane-1,2-dicarboxylic anhydride EC No.: 236-086-3 | CAS No.: 13149-00-3
Cyclohexane-1,2-dicarboxylic anhydride EC No.: 201-604-9 | CAS No.: 85-42-7
trans-cyclohexane-1,2-dicarboxylic anhydride EC No.: 238-009-9 | CAS No.: 14166-21-3
-
-
19/12/2012
Respiratory sensitising properties (Article 57(f) - human health)



Details
trimellitic anhydride; TMA
209-008-0
552-30-7
27/06/2018
Respiratory sensitising properties (Article 57(f) - human health)
Details
and all major diastereoisomers identified
show/hide
Hexabromocyclododecane EC No.: 247-148-4 | CAS No.: 25637-99-4
1,2,5,6,9,10-hexabromocyclododecane EC No.: 221-695-9 | CAS No.: 3194-55-6
alpha-hexabromocyclododecane EC No.: - | CAS No.: 134237-50-6
beta-hexabromocyclododecane EC No.: - | CAS No.: 134237-51-7
gamma-hexabromocyclododecane EC No.: - | CAS No.: 134237-52-8
-
-
28/10/2008
PBT (Article 57d)





Details
200-268-0
56-35-9
28/10/2008
PBT (Article 57d)
Details
204-371-1
120-12-7
28/10/2008
PBT (Article 57d)
Details
232-140-5
7789-00-6
18/06/2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
200-879-2
75-56-9
19/12/2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
200-589-6
64-67-5
19/12/2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
215-607-8
1333-82-0
15/12/2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details

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