Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
919-857-5
CAS no.:
-
Index number:
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
34
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance may be fatal if swallowed and enters airways, is a flammable liquid and vapour and may cause drowsiness or dizziness.

Breakdown of all 635 C&L notifications submitted to ECHA

Asp. Tox. 1 H304
Flam. Liq. 3 H226
STOT SE 3 H336
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 33 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases, adhesives and sealants, coating products and polishes and waxes.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).

This substance is used in the following products: coating products, hydraulic fluids and polishes and waxes.

This substance is used for the manufacture of: machinery and vehicles and textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use as processing aid, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following products: adhesives and sealants, coating products and lubricants and greases.

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in processing aids at industrial sites and formulation in materials.

This substance is used in the following products: lubricants and greases, coating products, leather treatment products, metal surface treatment products, metals, non-metal-surface treatment products, plant protection products, hydraulic fluids and polishes and waxes.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use non-sparking tools; ground and bond container and receiving equipment; avoid release to the environment; use explosion-proof equipment (electrical/ventilating/lighting/etc.); keep container tightly closed; avoid breathing the dust, fume, gas, mist, vapours or spray; take actions to prevent static discharges; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. Call a poison center or doctor/physician if you feel unwell. Do not induce vomiting. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Storage statements

Store this substance in a well-ventilated place and Keeping it cool; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL (OR1), Hermeslaan 7 1831 Diegem Belgium
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • B-Lands Consulting (811212-7), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • CEPSA Química, S.A., Edificio Torre Picasso Plaza Pablo Ruiz Picasso, 1 28020 Madrid Spain
  • CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Corporation, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • ENI, Piazzale Enrico Mattei 1 00144 Rome Italy
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • HH Compliance Ltd, Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland
  • HH Compliance Ltd., Rubicon Building, CIT Campus Bishopstown None Cork Ireland
  • INFO CARE BV - ATS SNO, Tiberiusweg 9 3453 KZ De Meern Netherlands
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • Knoell NL-OR-S06, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 05, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 06, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 16, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 33, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • MOL Hungarian Oil and Gas Public Limited Company, Dombóvári út 28 1117 Budapest Hungary
  • Neste Oyj, Keilaranta 21 FI-02150 Espoo Finland
  • NV Martin Mathys SA, Kolenbergstraat 23 3545 ZELEM Belgium
  • Polynt Composite SpA, via Enrico Fermi 51 24020 Scanzorosciate Bergamo Italy
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Rain Carbon Germany GmbH, Kekulestr. 30 44579 Castrop-Rauxel Germany
  • REACHLaw Ltd., Aleksanterinkatu 19 00100 Helsinki Finland
  • Silberline GmbH, Mellener Straße 6B 12305 Berlin Germany
  • Solenis Netherlands BV OR, Pesetastraat 62 2991 XT Barendrecht Netherlands
  • TotalEnergies Fluids, 2 Place Jean Millier 92078 PARIS La Défense Cedex France
  • TROY CHEMICAL COMPANY BV, Poortweg 4C 2612PA Delft Netherlands
  • Arakawa Europe GmbH, Hafenstr.2 04442 Zwenkau Germany
  • DHC Solvent Chemie GmbH, Timmerhellstraße 28 45478 Mülheim an der Ruhr Germany
  • Pioneer Europe Limted, 9 Stortford Hall Ind Est Dunmow Road CM235GZ Bishops Stortford Hertfordshire United Kingdom
  • SARPOM S.r.l., Viale Castello della Magliana 25 00148 Roma Italy
  • Shell Nederland Raffinaderij B.V., Vondelingenweg 601 Postbus 3000 3190 GA Rotterdam Netherlands Netherlands
  • Total Lindsey Oil Refinery ltd, Eastfield Road DN40 3LW North Lincolnshire United Kingdom

Substance names and other identifiers

Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, < 2% aromatics
REACH pre-registration
Anysol D40
Registration dossier
DS 150/200
Registration dossier
Hydrocarbons, C9-11, n-alkanes, isoalkanes, cyclics, <2% aromatics
Registration dossier
Hydrocarbons, C9-C11, isoalkanes, cyclics, < 2% aromatics
C&L Inventory
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, < 2%
C&L Inventory
HYDROCARBONS, C9-C11, N-ALKANES, ISOALKANES, CYCLICS, < 2% AROMATICS
C&L Inventory, Registration dossier
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, < 2% aromatics
Registration dossier
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, < 2% aromatics DOW BENELUX OR. 10
Registration dossier
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics
C&L Inventory, Registration dossier
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics
Registration dossier
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, aromatics, <2% aromatics
Registration dossier
Hydrogenated resin, recycled solvent
Registration dossier
Mineral spirit
Registration dossier
Not Applicable
Registration dossier
Exxsol D40 Naphtha (Sarnia)
Registration dossier
NESSOL D40
Registration dossier
Not Applicable
Registration dossier
Soltrol 100/125
Registration dossier

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [3]
C Form
Other (100%) [3]
C Odour
Slight (100%) [3]
C Substance type
Petroleum product (100%) [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 7 studies submitted
  • 3 studies processed
R Melting / freezing point
-50 °C @ 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 1 1 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 6 studies submitted
  • 3 studies processed
R Boiling point
155 - 192 °C @ 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 6 studies submitted
  • 3 studies processed
R Bulk density
0.776 g/cm³ @ 15 °C [1]
R Density
0.776 g/cm³ @ 15 °C [2]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 6 studies submitted
  • 3 studies processed
R Vapour pressure
2 hPa @ 20 °C [3]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Vapour pressure
3 hPa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Log Pow
3.17 - 6.23 @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
100 - 196 100 µg/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 4 studies submitted
  • 2 studies processed
R Flash point
39 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 4 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
200 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 2
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 6 studies submitted
  • 3 studies processed
R kinematic viscosity (in mm²/s)
1.33 [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 12 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 16 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 10 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 16 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 10 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 34 studies submitted
  • 28 studies processed
C Interpretation of results
Readily biodegradable (43%), Not inherently biodegradable (29%), Readily biodegradable but failing the 10-day window (14%), Inherently biodegradable (14%) [28]

Type of Study provided
Studies with data
Key study 2 26
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Adsorption/desorption

Study results
  • 2 studies submitted
  • 1 study processed
R Koc
465.69 - 140 184.5 L/kg @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.001 - 9.35 Pa m³/mol @ 20 °C and 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 4 studies submitted
  • 4 studies processed
% Distribution in Media:
R Air 80 % [4]
R Water 3.6 % [4]
R Soil 3.4 % [4]
R Sediment 13 % [4]
R Suspended sediment 0 % [4]
R Biota 0 % [4]
R Aerosol 0 % [4]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning No data available: testing technically not feasible (1)

Short–term toxicity to fish

Study results
  • 21 studies submitted
  • 21 studies processed
P/RResults
LL50 (4 days) 10 - 803 000 mg/L [21]
LL50 (72 h) 10 - 1 000 mg/L [11]
LL50 (48 h) 100 - 1 000 mg/L [11]
LL50 (24 h) 100 - 1 000 mg/L [11]
LL50 (3 h) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 3 18
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
EL10 (60 days) 200 µg/L [1]
NOELR (28 days) 131 µg/L [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 40 studies submitted
  • 40 studies processed
P/RResults
EC50 (48 h) 2 - 4 µg/L [6]
LC50 (4 days) 2 - 4 µg/L [12]
LL50 (4 days) 1 g/L [22]
LL50 (48 h) 1 - 10 g/L [4]
LL50 (24 h) 10 g/L [2]

Type of Study provided
Studies with data
Key study 2 38
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 6 studies processed
P/RResults
NOELR (21 days) 230 - 10 200 µg/L [6]

Type of Study provided
Studies with data
Key study 4 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 15 studies submitted
  • 6 studies processed
P/RResults
EL50 (72 h) 100 - 1 000 mg/L [8]
NOELR (72 h) 3 - 100 mg/L [8]

Type of Study provided
Studies with data
Key study 2 4
Supporting study 1 8
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
EC10 (3 h) 1 g/L [2]

Type of Study provided
Studies with data
Key study 4 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 15 studies submitted
  • 2 studies processed
P/RResults
NOEC (28 days) 75.8 - 371 mg/kg sediment dw [4]
LOEC (28 days) 371 mg/kg sediment dw [2]

Type of Study provided
Studies with data
Key study 14
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
other: (28 days) 91 - 476 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 871 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 77 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 185 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 46 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 46 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 60 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1 1 4
Supporting study 9 9 36
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 30 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 3 3 12
Supporting study 1 2 1 8
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 44 studies submitted
  • 26 studies processed
P/RResults
LD50 5 000 - 15 000 mg/kg bw (rat) [25]
M/CInterpretations of results
Not classified [24]

Type of Study provided
oral
Studies with data
Key study 2 24
Supporting study 1 1 16
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 50 studies submitted
  • 26 studies processed
P/RResults
LC50 (8 h) 5 mg/L air (rat) [4]
LC50 (8 h) 41 - 4 467 ppm (rat) [20]
LC50 (4 h) 4.951 - 9.3 mg/L air (rat) [13]
M/CInterpretations of results
Not classified [24]

inhalation
Studies with data
Key study 2 24
Supporting study 1 1 20
Weight of evidence
Other 1 1
Data waiving
no waivers
dermal
  • 26 studies submitted
  • 14 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [4]
LD50 3 160 - 5 000 mg/kg bw (rabbit) [9]
M/CInterpretations of results
Not classified [12]

dermal
Studies with data
Key study 2 12
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 15 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 6.1 mg/L air
Dermal route:
No adverse effect observed LD50 3 160 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 46 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 18
Supporting study 4 3 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 30 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2 16
Supporting study 1 1 9
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 6 9
Supporting study 1 1 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 28 studies submitted
  • 13 studies processed
P/RResults
NOAEL (rat): 500 - 5 000 mg/kg bw/day [9]
NOAEL (other:): 1 000 - 30 000 ppm [8]

Type of Study provided
Study data: oral
Studies with data
Key study 2 12
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: inhalation
  • 91 studies submitted
  • 15 studies processed
P/RResults
NOAEL (rat): 200 - 900 ppm [5]
NOAEC (rat): 275 - 10 400 mg/m³ air [14]

Study data: inhalation
Studies with data
Key study 1 4 12
Supporting study 1 1 72
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 3
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 6 000 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 54 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 8 32
Supporting study 1 1 12
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 23 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1 2 16
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 41 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 8
Supporting study 2 2 22
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 7
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 8
Supporting study 2
Weight of evidence 4
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Study data: developmental
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 4
Supporting study
Weight of evidence 2 4
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 2
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Effect on developmental toxicity
Inhalation route:
No adverse effect observed NOAEC 5 220 mg/m³ (subacute, rat)

Neurotoxicity

Study results
  • 33 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 3
Supporting study 5 5 18
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Dermal route:
No adverse effect observed NOAEL 2 000 mg/kg bw/day (subacute, rabbit)
Inhalation route:
No adverse effect observed NOAEC 11 600 mg/m³ (subacute, mouse)

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant