Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: hexasodium 4-amino-3-[2-(5-{[4-chloro-6-({3-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-2-sulfophenyl)diazen-1-yl]-6-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-5-hydroxynaphthalene-2,7-disulfonate
  • Substance names and other identifiers
EC / List no.:
401-310-2
CAS no.:
93912-64-2
Index number:
Molecular formula:
C37H23ClN10Na6O22S7
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].NC1=C2C(O)=C(N=NC3=CC=C4C(C=CC=C4S([O-])(=O)=O)=C3S([O-])(=O)=O)C(=CC2=CC(=C1N=NC1=C(C=CC(NC2=NC(Cl)=NC(NC3=CC=CC(=C3)S(=O)(=O)CCOS([O-])(=O)=O)=N2)=C1)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O
InChI:
InChI=1S/C37H29ClN10O22S7.6Na/c38-35-42-36(40-18-3-1-4-20(15-18)71(50,51)12-11-70-77(67,68)69)44-37(43-35)41-19-7-10-26(73(55,56)57)24(16-19)46-47-31-27(74(58,59)60)13-17-14-28(75(61,62)63)32(33(49)29(17)30(31)39)48-45-23-9-8-21-22(34(23)76(64,65)66)5-2-6-25(21)72(52,53)54;;;;;;/h1-10,13-16,49H,11-12,39H2,(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H2,40,41,42,43,44);;;;;;/q;6*+1/p-6
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
4
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
ELINCS (European LIst of Notified Chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye damage, may cause damage to organs and is harmful to aquatic life with long lasting effects.

Breakdown of all 36 C&L notifications submitted to ECHA

Not Classified
Eye Dam. 1 H318
STOT SE 2 H371
Aquatic Chronic 3 H412
Eye Irrit. 2 H319
Resp. Sens. 1 H334
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 13 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

This substance is used in the following products: coating products and textile treatment products and dyes.

Other release to the environment of this substance is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and leather (e.g. gloves, shoes, purses, furniture).

This substance is used in the following products: textile treatment products and dyes and coating products.

This substance is used in the following areas: printing and recorded media reproduction. This substance is used for the manufacture of: textile, leather or fur.

This substance is used in the following activities or processes at workplace: treatment of articles by dipping and pouring, calendering operations, transfer of substance into small containers and non-industrial spraying.

Other release to the environment of this substance is likely to occur from: indoor use.

This substance is used in the following products: leather treatment products, textile treatment products and dyes, paper chemicals and dyes, coating products, inks and toners and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: paper chemicals and dyes, leather treatment products and textile treatment products and dyes.

This substance is used for the manufacture of: pulp, paper and paper products, textile, leather or fur, wood and wood products and plastic products.

This substance is used in the following activities or processes at workplace: transfer of substance into small containers, transfer of chemicals at dedicated facilities, treatment of articles by dipping and pouring, roller or brushing applications, closed, continuous processes with occasional controlled exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: in the production of articles and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; do not eat, drink or smoke when using this product; avoid release to the environment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or you feel unwell: call a poison center or doctor/physician. Immediately call a poison center or doctor/physician. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • GAMMACOLOR SRL, via zeuner 5 20822 seveso Italy
  • Knoell NL_OR_056, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Reach & Colours Trade Kft, Levente u. 14/a 2161 Csomád Hungary
  • REACH&Colours Kft, Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary

Substance names and other identifiers

BLEU MARINO SUMIFIX SUPRA BF
REACH pre-registration
1,5-Naphthalenedisulfonic acid, 2-[2-[8-amino-7-[2-[5-[[4-chloro-6-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]diazenyl]-1-hydroxy-3,6-disulfo-2-naphthalenyl]diazenyl]-, sodium salt (1:6)
Other
2,7-Naphthalenedisulfonic acid, 4-amino-6-[[5-[[4-chloro-6-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]-2,6-disulfonaphthyl]azo]-5-hydroxy-3-[(4-sulfophenyl)azo]-, pentasodium salt
C&L Inventory
BLEU MARINO SUMIFIX SUPRA BF; C.I. REACTIVE BLUE 222; EVERZOL SUPRA NAVY BLUE FBN; REACTIVE BLUE 222; REACTIVE NAVY BLUE 303; SF. SUPRA NAVY BLUE BF; SUMIFIX SUPRA NAVY BLUE BF
C&L Inventory
Everzol Supra Navy Blue FBN
Registration dossier
Hexasodium 2-[8-amino-7-[[5-[[4-chloro-6-[[3-[[2-(sulfato)ethyl]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl] amino]-2 sulfonatophenyl]azo]-1-hydroxy-3,6-disulfonato-2-naphthalenyl]azo]-naphthalene-1,5-disulfonate
Registration dossier
hexasodium 4-amino-3-[2-(5-{[4-chloro-6-({3-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-2-sulfophenyl)diazen-1-yl]-6-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-5-hydroxynaphthalene-2,7-disulfonate
Registration dossier, Other
REACTIVE BLUE 222
C&L Inventory, Registration dossier
Reactive Navy Blue 303
Registration dossier
93051-44-6
CAS number
C&L Inventory
93051-94-6
CAS number
C&L Inventory
93912-64-2
CAS number
C&L Inventory, Registration dossier, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 9 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [3]
C Form
Powder (67%), Solid: particulate/powder (33%) [3]
C Odour
Odourless (100%) [2]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 5
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 8 studies submitted
  • 2 studies processed
R Relative density
1.833 - 1.91 @ 20 - 23 °C [2]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.83

Vapour pressure

Study results
  • 8 studies submitted
  • 2 studies processed
R Vapour pressure
0 - 0 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other 4
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 8 studies submitted
  • 2 studies processed
R Log Pow
-4.2 - -2.56 @ 20 °C and pH 5.56 - 6 [2]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-2.56 @ 20 °C

Water solubility

Study results
  • 8 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
71.733 - 189.27 g/L @ 20 °C and pH 4.8 - 5.29 [2]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
189.27 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Surface tension

Study results
  • 7 studies submitted
  • 2 studies processed
R Surface tension
60.8 - 62.7 mN/m @ 2.1 - 4.7 g/L and 20 °C [4]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 5
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
299 °C

Flammability

Study results
  • 7 studies submitted
  • 1 study processed
C Interpretation of results
Non flammable (100%) [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 7 studies submitted
  • 2 studies processed
C Interpretation of results
Non-explosive (50%), GHS criteria not met (50%) [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 7 studies submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 1 study processed
C Interpretation of results
Not readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 310 µg/L (1)
Intermittent releases (freshwater) 1 mg/L (1)
Marine water 31 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 7.84 µg/kg sediment dw (1)
Sediment (marine water) Insufficient data available (further information necessary) (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 11.9 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 1 g/L [1]
LC50 (72 h) 1 g/L [1]
LC50 (48 h) 1 g/L [1]
LC50 (24 h) 1 g/L [1]
NOEC (4 days) 1 g/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 7 studies submitted
  • 2 studies processed
P/RResults
EC50 (24 h) 1 g/L [2]
NOEC (24 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 9 studies submitted
  • 3 studies processed
P/RResults
EC50 (72 h) 100 mg/L [6]
NOEC (72 h) 100 mg/L [5]
LOEC (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 8 studies submitted
  • 2 studies processed
P/RResults
IC50 (3 h) 1 g/L [2]
NOEC (3 h) 1 g/L [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Acute toxicity

Study results
oral
  • 7 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
inhalation
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
dermal
  • 6 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Practically nontoxic [1]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 6 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 200 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 200 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Study data: in vivo
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Study data: developmental
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant