Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
290-058-5
CAS no.:
90063-97-1
Index number:
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Other
Registered compositions:
55
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance is toxic to aquatic life with long lasting effects, is harmful if swallowed, causes serious eye irritation, causes skin irritation and may cause an allergic skin reaction.

Breakdown of all 1807 C&L notifications submitted to ECHA

Skin Irrit. 2 H315
Skin Sens. 1 H317
Aquatic Chronic 2 H411
Acute Tox. 4 H302
Eye Irrit. 2 H319
Aquatic Chronic 3 H412
Not Classified
Asp. Tox. 1 H304
Flam. Liq. 3 H226
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Eye Dam. 1 H319
Aquatic Chronic 3 H413
Skin Sens. 1A H317
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (3.92% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 49 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, cosmetics and personal care products, air care products, polishes and waxes and biocides (e.g. disinfectants, pest control products).

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: cosmetics and personal care products, polishes and waxes and washing & cleaning products.

This substance is used in the following areas: health services.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring and closed, continuous processes with occasional controlled exposure.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following products: perfumes and fragrances and cosmetics and personal care products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, mixing in open batch processes, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: washing & cleaning products, perfumes and fragrances and pharmaceuticals.

This substance is used in the following areas: health services. This substance is used for the manufacture of: food products and chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, industrial spraying, closed processes with no likelihood of exposure, roller or brushing applications, batch processing in synthesis or formulation with opportunity for exposure and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and in the production of articles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, laboratory work and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment; do not get in eyes, on skin, or on clothing; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Collect spillage.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ADM WILD Europe GmbH & Co. KG, Rudolf-Wild-Strasse 107-115 69214 Eppelheim Baden-Württemberg Germany
  • BERNARDI, Parc Industriel Les Bois de Grasse Avenue Michel Chevalier 06130 GRASSE France
  • Biolandes, Route de Belis 40420 Le Sen Landes France
  • C.S.B. GmbH 0261, Dujardinstr. 5 47829 Krefeld Germany
  • Caplinq Europe B.V., Industrieweg 15E 1566JN Assendelft - Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Claus Nitsche & Sohn GmbH, Billbrookdeich 122 22113 Hamburg Germany
  • Duellberg Konzentra GmbH & Co. KG, Obenhauptstr.3 22335 Hamburg Hamburg Germany
  • elixens france SAS, Ecosite du Val de Drôme 428 rue Brunelle 26400 EURRE France
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • F.D.Copeland & Sons (Europe) Limited, 38 Upper Mount street D02 PR89 Dublin Ireland
  • FIRMENICH GRASSE SAS, Zi les Bois de Grasse Boulevard Emmanuel Rouquier 06130 GRASSE France
  • FIRMENICH GRASSE SAS OR, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • FIRMENICH GRASSE SAS OR 1, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • Frey + Lau GmbH, Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany
  • Givaudan France SAS - OR2, 55, Rue de la voie des Bans 95102 Argenteuil Cedex France
  • Global Essence Europe B.V, P.O. Box 67 ZH 4254 Sleeuwuk Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
  • GOLGEMMA SA, route de FA 11260 ESPERAZA Languedoc Roussillon France
  • H. REYNAUD & FILS, La Cheminade 26570 MONTBRUN LES BAINS France
  • International Flavors & Fragrances I.F.F. (Nederland) B.V., Liebergerweg 72-98 1221 JT Hilversum Netherlands
  • Intertek Deutschland GmbH ICFP, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Johann Voegele KG, Bahnhofstrasse 143 74348 Lauffen Baden-Württemberg Germany
  • John Kellys Europe B.V., Vogelenzang straat 15 2 10585N Amsterdam Netherlands
  • Khush Ingredients BV, Hart van Brabantlaan 12 5038 JM Tilburg Noord Brabant Netherlands
  • MANE OR Cinncinati, 620 route de Grasse 06620 LE BAR SUR LOUP France
  • Prinova Benelux & France N.V. / S.A., Landries 6 9420 Erpe Mere Belgium
  • QUIMDIS SAS, 71, rue Anatole France 92532 Levallois-Perret France
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • REACHLaw Ltd(acting as OR for Herbochem Industries Pvt. Ltd ), Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Robertet, 37 Avenue Sidi Brahim 06130 Grasse France
  • Sacmar s.r.l., Via keplero 7 20019 Settimo Milanese MI Italy
  • Sensient Technologies Europe GmbH, Geesthachter Straße 103 21502 Geesthacht Germany
  • Symrise AG, Mühlenfeldstraße 1 37603 Holzminden Germany
  • Symrise Granada, S.A.U., Crta. Armilla Km 2,5 18100 Armilla Granada Spain
  • V. MANE FILS , 620 route de Grasse 06620 Le Bar sur Loup France
  • Vossen & Co NV/SA, Av. Van Volxem 264, C1 1190 Brussels Belgium
  • WANXIANG IRELAND FLAVORS & FRAGRANCES CO., LIMITED, 302, THE CAPEL BUILDING, MARY’S ABBEY DUBLIN 7 Dublin Ireland
  • Yordas GmbH, Yordas GmbH Äußere Nürnberger Straße 62 91301 Forchheim Germany
  • Augustus Oils Ltd, Augustus House Mill Lane GU34 2QG Alton Hampshire United Kingdom
  • Khush Ingredients Limited, 14 Oakfield Industrial Estate Eynsham OX29 4TH Witney Oxfordshire United Kingdom

Substance names and other identifiers

Mentha arvensis, ext.
EC Inventory
Mentha arvensis, ext.
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Mentha arvensis, Labiatae.
REACH pre-registration
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol; (2R,5S)-5-methyl-2-(propan-2-yl)cyclohexan-1-one
Registration dossier, Other
CORNMINT (Mentha arvensis) ESSENTIAL OIL
C&L Inventory
Cornmint Oil
C&L Inventory
Cornmint oil
C&L Inventory, Registration dossier
Cornmint oil, Crude cornmint oil, Cornmint DMO
Registration dossier
Cornmint oil, low-terpene content
Registration dossier
Essential oil extract of Mentha arvensis (Laminaceae alt. Labiatae) leaves
C&L Inventory
Essential oil of Cornmint obtained from the herb of Mentha Arvensis Linn (Lamiaceae) by distillation
Registration dossier
Essential oil of Cornmint obtained from the herb of Mentha Arvensis Linn (Lamiaceae) by distillation
Registration dossier
HE Mentha arvensis
C&L Inventory
MENTA ARVENSIS
C&L Inventory
Menth arvensis leaf oil terpeneless
C&L Inventory
mentha arvensis
C&L Inventory
Mentha Arvensis
Registration dossier
Mentha arvensis essential oil
C&L Inventory
Mentha arvensis extract
C&L Inventory
Mentha arvensis extracts
C&L Inventory
Mentha Arvensis Leaf Oil
C&L Inventory
MENTHA ARVENSIS OIL
C&L Inventory, Registration dossier
Mentha arvensis, ext
C&L Inventory, Registration dossier
Mentha arvensis, ext
Registration dossier
Mentha arvensis, ext.
C&L Inventory, Registration dossier
Mentha arvensis, ext.
C&L Inventory, Registration dossier
Mentha arvensis, Extract
C&L Inventory
Menthe arvensis essential oil
C&L Inventory
Menthe arvensis oil
C&L Inventory
Mint arvensis oil
C&L Inventory
Mint oil
C&L Inventory
MINT OIL 70 %MINT OILMENTHA ARVENSIS OILMINT OIL RECT. 2 FOLDMINT OIL 87/10 WASHEDMINT OIL ARVENSIS 50 %MINT OIL 50 %MINT OIL 70 %MINT OIL 78 %MINT OIL RECT. JAPAN TYPEMINT TERPENES WASHEDMINT TERPENESMINT OIL DMO 70 %MINT OIL TRIPLE RECT.MINT OIL RECT. - LOW TERPENESMINT OIL 87 %
Registration dossier
PEPPERMINT OIL
C&L Inventory
Peppermint oil / Cornmint oil from Mentha arvensis
C&L Inventory
Reaction mass of pin-2(3)-ene and menthol and trans-menthone and 7-methyl-3-methyleneocta-1,6-diene and pin-2(10)-ene and isomenthone and 4,5,6,7-tetrahydro-3,6-dimethylbenzofuran and (R)-p-mentha-1,8-diene
C&L Inventory
Reaction mass of pin-2(3)-ene and menthyl acetate and menthol and p-menth-4(8)-en-3-one and (S)-p-mentha-1,8-diene and p-menthan-3-one
C&L Inventory
Reaction mass of pin-2(3)-ene and menthyl acetate and p-menth-4(8)-en-3-one and pin-2(10)-ene and isomenthone and L-menthol and (+)-neomenthol and (R)-p-mentha-1,8-diene and p-menthan-3-one
C&L Inventory
Cornmint Oil
Registration dossier
Dementholised oilCornmint oilPeppermint oil
Registration dossier
Dementholized peppermint oil
Registration dossier
DMO
Registration dossier
Mentha Arvensis
Registration dossier
MENTHA ARVENSIS DEMENTHOLIZED EO
Registration dossier
MENTHA ARVENSIS DEMENTHOLIZED LOW TERPENES EO
Registration dossier
MENTHA ARVENSIS OIL, CORNMINT OIL, DEMENTHOLIZED MINT OIL, MENTHA ARVENSIS TERPENES
C&L Inventory
Mentha arvensis, ext
Registration dossier
MENTHE ARVENSIS DMO DTP HE
Registration dossier
MENTHE ARVENSIS DMO HE
Registration dossier
MENTHE DMO 50% INDE HE
Registration dossier
MENTHE DMO DETERPENEE HE
Registration dossier
MENTHE RECTIFIEE HE
Registration dossier
MENTHE TRI-RECTIFIEE HE
Registration dossier
Mint blend terpeneless Yakima type
Registration dossier
MINT DMO 50% EO INDIA
Registration dossier
MINT DMO 50% OIL
Registration dossier
MINT DMO LOW TERPENES EO
Registration dossier
MINT DMO LOW TERPENES OIL
Registration dossier
MINT DMO TERPENELESS EO
Registration dossier
Mint oil Bras. Roh
Registration dossier
Mint oil chin.
Registration dossier
MINT OIL CHIN. DEMENTHOLIZED
Registration dossier
Mint oil dementholised
Registration dossier
Mint oil deterpenated
Registration dossier
Mint oil Ind. Terpenfrei
Registration dossier
MINT OIL INDIA 70% (ORGANIC BIO)
Registration dossier
Mint oil Indisch Ph. Eur.
Registration dossier
MINT OIL JAPAN TYPE
Registration dossier
Mint oil Piperita type
Registration dossier
MINT OIL RECTIFIED
Registration dossier
MINT RECTIFIED EO INDIA
Registration dossier
Mosa mint oil
Registration dossier
Nemo mint oil
Registration dossier
Peppermint crystal white
Registration dossier
Peppermint IND RECT (FDC) DQ AC414
Registration dossier
Peppermint INDIAN TPC-1 DQ AC 24049
Registration dossier
peppermint oil
Registration dossier
Peppermint oil Idaho type
Registration dossier
Peppermint oil Madras type
Registration dossier
Peppermint oil Midwest type
Registration dossier
Peppermint oil Williamette type
Registration dossier
Peppermint oil Yakima Double cut type
Registration dossier
Peppermint oil Yakima type
Registration dossier
Spearmint Oil
Registration dossier
68608-35-5
CAS number
C&L Inventory
68917-18-0
CAS number
C&L Inventory
90063-97-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Odour
Other (100%) [2]
C Substance type
Natural substance (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
-25 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-74 °C

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
102 °C @ 100 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
102 - 176 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Density
0.893 g/cm³ @ 20 °C [2]
R Relative density
0.894 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.894

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
50.8 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
50.8 - 200 Pa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 2 studies processed
R Log Pow
2.73 - 6.99 @ 25 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Log Kow (Log Pow)
4.38 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
500 - 943 200 µg/L @ 20 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Water solubility
12.3 mg/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
68.7 °C @ 100 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
68.7 °C

Auto flammability

Study results
  • 2 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
285 °C @ 100.94 - 101.42 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Autoflammability / self-ignition at 101 325 Pa
285 °C

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 2 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
5.54 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Static viscosity at 20 °C
5.54 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Readily biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
683 L/kg ww

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
2 413

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 3 summaries submitted
  • 3 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 5.4 µg/L (1)
Intermittent releases (freshwater) 5.77 µg/L (1)
Marine water 540 ng/L (1)
Intermittent releases (marine water) No data available: testing technically not feasible (2)
Sewage treatment plant (STP) 1.8 mg/L (1)
Sediment (freshwater) 1.3 mg/kg sediment dw (1)
Sediment (marine water) 130 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (3)
Hazard for Terrestrial Organism
Soil 290 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential to cause toxic effects if accumulated (in higher organisms) via the food chain (3)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 3.01 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 2.43 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 2.63 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
2.63 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 35.3 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (Medium hazard (no threshold derived)) -
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.7 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.5 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (Medium hazard (no threshold derived)) -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.5 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 5 5 5
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Absorption values
Oral: 100 %
Dermal: 100 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 2 studies processed
M/CInterpretations of results
Harmful [1]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
dermal
  • 2 studies submitted
  • 2 studies processed
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 1 240 mg/kg bw
Dermal route:
No adverse effect observed LD50 5 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence 3 1 1
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 27 studies submitted
  • 7 studies processed
P/RResults
NOAEL (rat): 375 - 600 mg/kg bw/day [5]
NOAEL (rat): 7 500 ppm [1]
NOAEL (mouse): 250 - 500 mg/kg bw/day [3]
LOAEL (rat): 100 - 1 200 mg/kg bw/day [5]
LOAEL (mouse): 1 000 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1 1 1
Supporting study 2 7
Weight of evidence 5 5
Other 4
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: inhalation
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 200 ppm [1]
NOAEL (mouse): 50 ppm [1]
LOAEL (rat): 25 ppm [1]

Study data: inhalation
Studies with data
Key study
Supporting study 2
Weight of evidence 2 2
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
No adverse effect observed NOAEL 400 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence 1 1 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 3
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 1
Weight of evidence 5 5 6
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant