Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: (2R)-2,3-dihydroxypropyl octadecanoate 2,3-dihydroxypropyl hexadecanoate 2-hydroxy-3-(octadecanoyloxy)propyl octadecanoate 3-(hexadecanoyloxy)-2-hydroxypropyl octadecanoate
  • Substance names and other identifiers
EC / List no.:
286-490-9
CAS no.:
85251-77-0
Index number:
Molecular formula:
C116H228O18
SMILES:
CCCCCCCCCCCCCCCC(=O)OCC(O)CO.CCCCCCCCCCCCCCCCCC(=O)OC[C@H](O)CO.CCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCC.CCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCCCC
InChI:
InChI=1S/C39H76O5.C37H72O5.C21H42O4.C19H38O4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-35-37(40)36-44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(40)42-34-35(38)33-41-36(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h37,40H,3-36H2,1-2H3;35,38H,3-34H2,1-2H3;20,22-23H,2-19H2,1H3;18,20-21H,2-17H2,1H3/t;;20-;/m..1./s1
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
33
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 225 C&L notifications submitted to ECHA

Not Classified
Aquatic Chronic 3 H412
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 37 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000+ tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, fertilisers and coating products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: formulation in materials, in processing aids at industrial sites and as processing aid. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

This substance can be found in products with material based on: rubber (e.g. tyres, shoes, toys).

This substance is used in the following products: washing & cleaning products and polishes and waxes.

This substance is used in the following areas: formulation of mixtures and/or re-packaging, printing and recorded media reproduction and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, plastic products, food products and textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, treatment of articles by dipping and pouring, batch processing in synthesis or formulation with opportunity for exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: polymers, washing & cleaning products, lubricants and greases, paper chemicals and dyes, cosmetics and personal care products, pharmaceuticals and metal working fluids.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers, closed batch processing in synthesis or formulation, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: washing & cleaning products, polymers, metal surface treatment products, lubricants and greases, textile treatment products and dyes and pH regulators and water treatment products.

This substance is used in the following areas: formulation of mixtures and/or re-packaging, municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and printing and recorded media reproduction. This substance is used for the manufacture of: chemicals, plastic products, food products and textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, transfer of substance into small containers, closed batch processing in synthesis or formulation, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, transfer of substance into small containers, mixing in open batch processes and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • B.B.C. srl, Largo delle Industrie 11 24020 Torre Boldone Bergamo Italy
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • Cargill B.V., Evert van de Beekstraat 378 1118 CZ Amsterdam Schiphol North Holland Netherlands
  • Croda EU B.V. (OR2), Buurtje 1 2802 BE Gouda Netherlands
  • Emery Oleochemicals GmbH, Paul-Thomas-Straße 56 D-40599 Duesseldorf Germany
  • Erca Wilmar Cosmetic Ingredients Sp. z o.o., Mianowskiego 3 lok. 6 02-044 Warszawa Poland
  • FACI S.p.A. OR1, Via Privata Devoto, 36 16042 Carasco Italy
  • FACI SPA, Via Privata Devoto 36 16042 Carasco Italy
  • GATTEFOSSE SAS, 36 chemin de genas CS70070 FR-69804 Saint Priest France France
  • GEMEY MAYBELLINE GARNIER, 16 place Vendôme 75001 PARIS France
  • Green Oleo S.R.L., Via Quintino Sella 4 20121 Milano Lombardia Italy
  • Hallstar Italia Srl con socio unico , Piazza Meda, 3 20121 Milano Lombardia Italy
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Inolex GmbH, Unter den Linden 21 10117 Berlin Germany
  • IOI Oleo GmbH, Herrengraben 31 20459 Hamburg Germany
  • Kerry (NL) B.V., Lindtsedijk 8 3336 LE Zwijndrecht Netherlands Netherlands
  • L OREAL UK LTD, 255, Hammersmith Road W6 8AZ LONDON United Kingdom
  • L'OREAL DEUTSCHLAND GmbH, Herzstrasse 175 D-76187 KARLSRUHE Germany
  • L'OREAL ITALIA S.p.A., Via Primaticcio n°155 20147 MILANO Italy
  • L'OREAL PRODUITS DE LUXE INTERNATIONAL, 106 rue Danton 92300 LEVALLOIS PERRET France
  • LASCAD, 7 rue Touzet 93400 Saint Ouen France
  • Lasenor Emul, Ctra C55 Km5.3 08640 Olesa de Montserrat Barcelona Spain
  • N.V. Cargill, Muisbroeklaan 43 B-2030 Antwerp Belgium
  • OLEON N.V., Industriezone "ter straten" Vaartstraat 220 2520 Oelegem Belgium
  • Oleon N.V., Assenedestraat 2 9940 Ertvelde Belgium
  • Palsgaard A/S, Palsgaardvej 10 7130 Juelsminde Denmark
  • Peter Greven GmbH & Co. KG, Peter-Greven-Str. 20-30 53902 Bad Münstereifel Germany
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Lopez Bravo n°78 Poligono Industrial Villalonquéjar 09001 BURGOS Spain
  • SABO SPA, Via Caravaggi 24040 Levate Bergamo Italy
  • Schill+Seilacher "Struktol" GmbH Hamburg, Moorfleeter Straße 28 22113 Hamburg Germany
  • SO.G.I.S. Industria Chimica S.p.A., Via Giuseppina, 132 26048 Sospiro (CR) Italy
  • Societe Industrielle des Oleagineux, 16 rue du General de Gaulle 62223 Saint Laurent Blangy France
  • STEARINERIE DUBOIS, Scoury 36300 CIRON France
  • UNION DERIVAN S.A, C/ Comte d´Urgell 240, 4D 08036 Barcelona Barcelona Spain
  • [Confidential], [Confidential]
  • Emery Oleochemicals GmbH, Paul Thomas Straße 56 40599 Duesseldorf Germany

Substance names and other identifiers

Glycerides, C16-18 mono- and di-
EC Inventory, REACH pre-registration, Other
Glyceryl mono and dipalmitostearate
Other
(1-hexadecanoyloxy-3-hydroxypropan-2-yl) octadecanoate
Registration dossier, Other
(2R)-2,3-dihydroxypropyl octadecanoate 2,3-dihydroxypropyl hexadecanoate 2-hydroxy-3-(octadecanoyloxy)propyl octadecanoate 3-(hexadecanoyloxy)-2-hydroxypropyl octadecanoate
Registration dossier, Other
GELEOL
Registration dossier
Glycerides C16-18, mono and di
Registration dossier
Glycerides, C16-18 (even numbered) mono- and di-
Registration dossier
Glycerides, C16-18 mono- and di- (even numbered)
Registration dossier
Glycerides, C16-18 mono-and di-
Registration dossier
Glycerides, C16-18 monoglycerides and diglycerides
Registration dossier
Glycerides, C16-18, mono- and di- 85251-77-0
Registration dossier
Glycerides, C16-C18 mono- di-
Registration dossier
MDG, Saturated
Registration dossier
Mono and diglycerides of fatty acids
Registration dossier
Mono- and diglycerides of fatty acids
Registration dossier
Mono-(C16-18)-acylglycerol and Di-(C16-18)-acylglycerol
Registration dossier
BC 130
Registration dossier
CHINT: FCE (glycerol)mono/diE C16-18
Registration dossier
Cithrol 0795
Registration dossier
Cithrol GMS-30
Registration dossier
Cithrol GMS-40
Registration dossier
DUB GMS
Registration dossier
GMS
Registration dossier
Imwitor 900 K
Registration dossier
Imwitor 900 P
Registration dossier
PALMSURF GMS 40
Registration dossier
PALMSURF GMS 40SE
Registration dossier
PALMSURF GMS 50
Registration dossier
PALMSURF GMS 50SE
Registration dossier
Phase I REACH Kandidat
Registration dossier
RADIAMULS MG 2120K
Registration dossier
RADIAMULS MG 2142K
Registration dossier
RADIAMULS MG 2143
Registration dossier
RADIAMULS MG 2143K
Registration dossier
RADIAMULS MG 2146
Registration dossier
RADIAMULS MG 2164K
Registration dossier
RADIAMULS MG 2165K
Registration dossier
RADIAMULS MG 2341
Registration dossier
RADIAMULS MG 2342
Registration dossier
RADIAMULS MG 2364K
Registration dossier
RADIAMULS MG 2542K
Registration dossier
RADIAMULS MG 2543K
Registration dossier
RADIAMULS MG 2604K
Registration dossier
RADIAMULS MG 2642K
Registration dossier
RADIAMULS MG 2643
Registration dossier
RADIAMULS MG 2643K
Registration dossier
RADIAMULS MG 2644K
Registration dossier
RADIAMULS MG 2646K
Registration dossier
RADIAMULS MG 2655
Registration dossier
RADIAMULS MG 2923K
Registration dossier
RADIASURF 7140
Registration dossier
RADIASURF 7142
Registration dossier
RADIASURF 7143
Registration dossier
RADIASURF 7340
Registration dossier
RADIASURF 7342
Registration dossier
RADIASURF 7343
Registration dossier
RADIASURF 7344
Registration dossier
RADIASURF 7346
Registration dossier
RADIASURF 7600
Registration dossier
RADIASURF 7601
Registration dossier
RADIASURF 7641
Registration dossier
RADIASURF 7643
Registration dossier
RADIASURF 7644
Registration dossier
RADIASURF 7645
Registration dossier
2068707-19-5
Deleted CAS number
Other
85251-77-0
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Melting/freezing point

Study results
  • 6 studies submitted
  • 3 studies processed
R Melting / freezing point
56 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 3 studies submitted
  • 3 studies processed
R Density
0.92 - 0.96 g/cm³ @ 20 °C [12]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 3 studies submitted
  • 3 studies processed
R Vapour pressure
0 - 0 Pa @ 20 °C [12]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 3 studies submitted
  • 3 studies processed
R Log Pow
5.63 - 15.07 [12]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 6 studies submitted
  • 3 studies processed
R Water solubility (mass/vol.)
1 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 9 studies submitted
  • 6 studies processed
R Flash point
240 °C @ 101.3 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.002 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LC0 (4 days) 10 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 10 - 100 000 µg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 10 µg/L [2]
LOEC (21 days) 10 µg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (72 h) 10 - 100 000 µg/L [4]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 125.04 mg/m³ -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 17.73 mg/kg bw/day -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 30.83 mg/m³ -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.86 mg/kg bw/day -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.86 mg/kg bw/day -
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (6 h) 1.86 mg/L air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 4 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 5 000 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant