Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
284-521-0
CAS no.:
84929-38-4
Index number:
Molecular formula:
C20H32
SMILES:
CC(C)C1=CCC(C)=CC1.CC(=C)C1CCC(C)=CC1
InChI:
InChI=1/2C10H16/c2*1-8(2)10-6-4-9(3)5-7-10/h4,7-8H,5-6H2,1-3H3;4,10H,1,5-7H2,2-3H3
Type of substance:
UVCB
Origin:
Other
Registered compositions:
33
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance may be fatal if swallowed and enters airways, is toxic to aquatic life with long lasting effects, is a flammable liquid and vapour, causes skin irritation and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is very toxic to aquatic life with long lasting effects and is very toxic to aquatic life.

Breakdown of all 1761 C&L notifications submitted to ECHA

Skin Sens. 1 H317
Skin Irrit. 2 H315
Asp. Tox. 1 H304
Flam. Liq. 3 H226
Aquatic Chronic 1 H410
Aquatic Acute 1 H400
Aquatic Chronic 2 H411
Aquatic Acute 2 H401
Aquatic Chronic 2 H410
Flam. Liq. 2 H225
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 34 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 - 1 000 tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: air care products, biocides (e.g. disinfectants, pest control products), polishes and waxes, washing & cleaning products and cosmetics and personal care products.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: polishes and waxes and washing & cleaning products.

This substance is used in the following areas: mining. This substance is used for the manufacture of: textile, leather or fur, wood and wood products, chemicals and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, roller or brushing applications, non-industrial spraying, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid.

This substance is used in the following products: perfumes and fragrances.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of substance into small containers, laboratory work and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products) and metal surface treatment products.

This substance is used in the following areas: mining. This substance is used for the manufacture of: chemicals and machinery and vehicles.

This substance is used in the following activities or processes at workplace: industrial spraying, transfer of chemicals at dedicated facilities, roller or brushing applications, treatment of articles by dipping and pouring, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and in the production of articles.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of chemicals at dedicated facilities.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and Keeping it cool.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Agrumaria Corleone SpA, via Salvatore Corleone 12 I-90124 Palermo Italy
  • AMEDEO GIOVANNI SRL, ANITA GARIBALDI Var. 26 89135 REGGIO CALABRIA Italy
  • ASTIER-DEMAREST S.A., 60, route de la Paoute 06130 GRASSE France
  • Capua 1880 S.r.l., Zona Industriale 89052 Campo Calabro Reggio Calabria Italy
  • CILIONE S.r.l., via S. Antonio Arangea 89132 Reggio Calabria Italy
  • CITROFLOR S.R.L., Contrada Vivo snc 89030 Condofuri Marina RC-CALABRIA Italy
  • CITROMIL, S.L., Carretera de Abanilla, Km 1.6 30140 Santomera Murcia Spain
  • DIEGO VISALLI SRL UNIPERSONALE, Via Pallica n°50 89063 Melito di Porto Salvo (Reggio Calabria) Italy
  • E.S.A.V. ESSENZE E SUCCHI DI AGRUMI VILLABATE DI LO MEO GIOVANNI & C. S.N.C., VIA PABLO PICASSO N. 2 90039 VILLABATE PALERMO Italy
  • Erich Ziegler GmbH, Am Weiher 133 91347 Aufsess Germany
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • F.lli Branca SpA, Via Maceo,7 98050 Terme Vigliatore (ME) Italy
  • FIRMENICH GRASSE SAS OR 1, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • FIRMENICH GRASSE SAS OR 7, Parc Industriel Le Bois de Grasse 06130 Grasse France
  • Frey + Lau GmbH, Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany
  • Gioia Succhi S.r.l., Prima Zona Industriale 89026 San Ferdinando RC Italy
  • Givaudan France SAS - OR1, 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France
  • Givaudan France SAS - OR2, 55, Rue de la voie des Bans 95102 Argenteuil Cedex France
  • GOLGEMMA SA, route de FA 11260 ESPERAZA Languedoc Roussillon France
  • HELPAC, DISTILLERIE DE SAINT HILAIRE 43390 SAINT HILAIRE France
  • I.A.C. di G. Di Bartolo srl, Corso Italia, 271 95014 Giarre (Catania) Italy
  • INDUKERN, S.A., Alta Ribagorza, 6-8 08820 El Prat de Llobregat Barcelona Spain
  • J C Buck Limited, Unit 8, The Stafford Estate Hillman Close, Ardleigh Green RM11 2SJ Hornchurch Essex United Kingdom
  • Johann Voegele KG, Bahnhofstrasse 143 74348 Lauffen Baden-Württemberg Germany
  • LLUCH ESSENCE, S.L., Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain
  • MCI Miritz Citrus GmbH & Co. KG, Citrusstraße 3 37318 Kirchgandern Germany
  • Miguel Parra e Hijos, S.A., Ctra. Abanilla, Km.1 30140 Santomera Murcia Spain
  • Misitano & Stracuzzi S.p.A., Via Ghibellina, 64 98122 Messina Italy
  • PRODARESS, P.A. du Pilon, Lot N° 3 06460 SAINT VALLIER DE THIEY France
  • R.C.Treatt & Co. Ltd., Northern Way IP32 6NL Bury St. Edmunds Suffolk United Kingdom
  • RIVERBEND ESPAÑA, S.L., Crta. ABANILLA Km. 1.5 30140 SANTOMERA MURCIA Spain
  • SAT 1596 NUFRI, Carretera de Palau Km 1 25230 Mollerussa Lérida Spain
  • SIMONE GATTO srl, C.DA S. BIAGIO 98045 SAN PIER NICETO MESSINA Italy
  • Sunprod Srl, Via Sebastiano Catania 284 95123 Catania Italy

Substance names and other identifiers

Mandarin orange, ext.
EC Inventory, REACH pre-registration
1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; 1-methyl-4-(propan-2-yl)cyclohexa-1,4-diene
Other
Citrus Retitculata Leaf Oil
C&L Inventory
Essential oil of Mandarin obtained from the peel of Citrus nobilis, Rutaceae by expression and/or distillation, including cold-pressed, distilled, terpenes and essence qualities
Registration dossier
Essential oil of Mandarin obtained from the peelof Citrus nobilis, Rutaceae by expression and/ordistillation, including cold-pressed, distilled,
Registration dossier
HE Citrus reticulata
C&L Inventory
Mandarin Essential Oil
C&L Inventory
Mandarin green, ext.
C&L Inventory
MANDARIN OIL
C&L Inventory, Registration dossier
Mandarin orange essential oil
C&L Inventory
Mandarin orange oil
C&L Inventory
Mandarin orange, ext
C&L Inventory
Mandarinenöl
C&L Inventory
PETITGRAIN MANDARIN ESSENTIAL OIL
C&L Inventory
Reaction mass of pin-2(3)-ene and p-mentha-1,4-diene and 7-methyl-3-methyleneocta-1,6-diene and pin-2(10)-ene and (R)-p-mentha-1,8-diene
C&L Inventory
Satsuma mandarin oil
C&L Inventory
tangerine oil
C&L Inventory
Decolorized Mandarin oil
Registration dossier
Distilled Mandarin oil
Registration dossier
GREEN MANDARIN OIL
Registration dossier
Green Mandarin oil cold pressed
Registration dossier
HUILE ESSENTIELLE BIOLOGIQUE Mandarine Verte
C&L Inventory
HUILE ESSENTIELLE MANDARINE ROUGE BIOLOGIQUE
C&L Inventory
Mandarin Essence Oil
Registration dossier
Mandarin Essence Oil folded
Registration dossier
Mandarin Folded
Registration dossier
MANDARIN GREEN ITALIAN OIL
Registration dossier
Mandarin Oil 5-fold
Registration dossier
Mandarin Oil Argentina
Registration dossier
Mandarin oil cold pressed (yellow green and red)
Registration dossier
Mandarin Oil Cold pressed (yellow, green and red)
Registration dossier
Mandarin oil colorless
C&L Inventory
Mandarin Oil Colourless
Registration dossier
MANDARIN OIL COLS PRESSED
Registration dossier
Mandarin Oil Decolorized
Registration dossier
MANDARIN OIL DISTILLED
Registration dossier
MANDARIN OIL DM
Registration dossier
MANDARIN OIL EXPRESSED
Registration dossier
Mandarin Oil Folded
Registration dossier
Mandarin Oil Green
Registration dossier
Mandarin Oil Red
Registration dossier
MANDARIN OIL TERPENES
Registration dossier
MANDARIN OIL WW
Registration dossier
Mandarin Oil Yellow
Registration dossier
Mandarin Terpenes
Registration dossier
Mandarin Terpenes Decolorized Mandarin oil Distilled Mandarin oil Green Mandarin Oil Green Mandarin oil cold pressed Mandarin Essence Oil Mandarin Essence Oil folded Mandarin Oil 5-fold Mandarin Oil Argentina Mandarin Oil Cold pressed (yellow, green and red) Mandarin Oil Colourless Mandarin Oil Distilled Mandarin Oil Folded Mandarin Terpenes Red Mandarin Oil Red Mandarin oil cold pressed Waterwhite Mandarin oil Yellow Mandarin oil cold pressed
Registration dossier
MANDARINA AMARILLA AE
Registration dossier
MANDARINA VERTE
Registration dossier
MANDARINE INCOLORE
Registration dossier
MANDARINE ITALIE HE
Registration dossier
MANDARINE JAUNE HE
Registration dossier
MANDARINE ROUGE HE
Registration dossier
MANDARINE VERTE ESS.
Registration dossier
MANDARINE VERTE HE
Registration dossier
MANDARINO DISTILLATO
Registration dossier
MANDARINO INCOLORE
Registration dossier
O.E. MANDARINO GIALLO
Registration dossier
O.E. MANDARINO ROSSO
Registration dossier
O.E. MANDARINO VERDE
Registration dossier
Petitgrain mandarin oil
C&L Inventory
RED MANDARIN OIL
Registration dossier
RED MANDARIN OIL A1
Registration dossier
Red Mandarin oil cold pressed
Registration dossier
RED MANDARIN OIL SFUMATRICE
Registration dossier
Waterwhite Mandarin oil
Registration dossier
YELLOW MANDARIN OIL
Registration dossier
Yellow Mandarin oil cold pressed
Registration dossier
8008-31-9
CAS number
C&L Inventory
84696-35-5
Deleted CAS number
Other
84929-38-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
90063-82-4
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Natural substance (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
160 °C @ 101.6 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
160 °C

Density

Study results
  • 1 study submitted
  • 1 study processed
R Density
0.849 g/cm³ @ 20 °C [1]
R Relative density
0.851 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.851

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
2.087 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
2.087 hPa @ 25 °C

Partition coefficient

Study results
  • 1 study submitted
  • 1 study processed
R Log Pow
4.27 - 4.88 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
4.38

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
2.6 - 93.066 mg/L @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
51 °C @ 101.2 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
51 °C

Auto flammability

Study results
  • 3 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
235 °C @ 101.22 - 101.65 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
235 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 5.4 µg/L (1)
Intermittent releases (freshwater) 5.77 µg/L (1)
Marine water 540 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 2.1 mg/L (1)
Sediment (freshwater) 1.3 mg/kg sediment dw (1)
Sediment (marine water) 130 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 290 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential to cause toxic effects if accumulated (in higher organisms) via the food chain (1)

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LL50 (4 days) 100 mg/L [1]
EL0 (4 days) 10 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EL50 (48 h) 8.9 mg/L [1]
EL50 (24 h) 17 mg/L [1]
NOELR (48 h) 2.2 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
8.9 mg/L

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (72 h) 610 µg/L [1]
NOEC (72 h) 140 µg/L [1]
EL10 (72 h) 7.8 mg/L [2]
EL50 (72 h) 9.7 mg/L [2]
NOELR (72 h) 3.2 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
9.7 mg/L
EC10 or NOEC for freshwater algae
7.8 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.3 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 6.67 mg/kg bw/day repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: (DNEL) 185.8 µg/cm² sensitisation (skin)
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5.8 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.33 mg/kg bw/day repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: (DNEL) 92.9 µg/cm² sensitisation (skin)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.33 mg/kg bw/day repeated dose toxicity
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study 1
Weight of evidence 3
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 7 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 600 mg/kg bw/day [2]
NOAEL (mouse): 500 mg/kg bw/day [1]
NOAEL (dog): 100 mg/kg bw/day [1]
LOAEL (rat): 1 200 mg/kg bw/day [2]
LOAEL (dog): 1 000 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 2
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1
Supporting study
Weight of evidence 6
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant