Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Phenol, isopropylated, phosphate (3:1)
  • IUPAC name: diphenyl 4-(propan-2-yl)phenyl phosphate phenyl bis[4-(propan-2-yl)phenyl] phosphate triphenyl phosphate tris[4-(propan-2-yl)phenyl] phosphate
  • Other names
EC / List no.:
273-066-3
CAS no.:
68937-41-7
Index number:
Molecular formula:
C90H96O16P4
SMILES:
O=P(OC1=CC=CC=C1)(OC1=CC=CC=C1)OC1=CC=CC=C1.CC(C)C1=CC=C(OP(=O)(OC2=CC=CC=C2)OC2=CC=CC=C2)C=C1.CC(C)C1=CC=C(OP(=O)(OC2=CC=CC=C2)OC2=CC=C(C=C2)C(C)C)C=C1.CC(C)C1=CC=C(OP(=O)(OC2=CC=C(C=C2)C(C)C)OC2=CC=C(C=C2)C(C)C)C=C1
InChI:
InChI=1S/C27H33O4P.C24H27O4P.C21H21O4P.C18H15O4P/c1-19(2)22-7-13-25(14-8-22)29-32(28,30-26-15-9-23(10-16-26)20(3)4)31-27-17-11-24(12-18-27)21(5)6;1-18(2)20-10-14-23(15-11-20)27-29(25,26-22-8-6-5-7-9-22)28-24-16-12-21(13-17-24)19(3)4;1-17(2)18-13-15-21(16-14-18)25-26(22,23-19-9-5-3-6-10-19)24-20-11-7-4-8-12-20;19-23(20-16-10-4-1-5-11-16,21-17-12-6-2-7-13-17)22-18-14-8-3-9-15-18/h7-21H,1-6H3;5-19H,1-4H3;3-17H,1-2H3;1-15H AuxInfo=1/0/N:25,26,28,29,31,32,16,18,19,21,10,12,15,14,23,22,9,13,24,27,30,17,20,11,7,8,6,2,3,4,5,1;57,58,60,61,52,51,53,55,54,48,50,42,44,47,46,41,45,56,59,49,43,40,39,38,34,36,35,37,33;86,87,78,81,77,79,80,82,76,75,84,83,71,73,70,74,85,72,68,69,67,63,64,65,66,62;98,104,107,97,99,103,105,106,108,96,100,102,101,110,109,93,94,95,89,92,90,91,88/E:(1,2,3,4,5,6)(7,8,9,10,11,12)(13,14,15,16,17,18)(19,20,21)(22,23,24)(25,26,27)(29,30,31);(1,2,3,4)(6,7)(8,9)(10,11,12,13)(14,15,16,17)(18,19)(20,21)(23,24)(27,28);(1,2)(3,4)(5,6,7,8)(9,10,11,12)(13,14)(15,16)(19,20)(23,24);(1,2,3)(4,5,6,7,8,9)(10,11,12,13,14,15)(16,17,18)(20,21,22)/rA:110POOOOCCCCCCCCCCCCCCCCCCCCCCCCCCCPOOOOCCCCCCCCCCCCCCCCCCCCCCCCPOOOOCCCCCCCCCCCCCCCCCCCCCPOOOOCCCCCCCCCCCCCCCCCC/rB:d1;s1;s1;s1;s5;s3;s4;s6;d-9;s10;d-11;d+6s12;s7;d+7;s15;d-16;d-14s17;;s19;d-20;d+8s21;s8d-19;s17;s24;s24;s20;s27;s27;s11;s30;s30;;d33;s33;s33;s33;s37;s35;s36;s38;d-41;s42;d-43;d+38s44;s39;d+39;s47;d-48;d-46s49;;s51;d-52;d+40s53;s40d-51;s49;s56;s56;s43;s59;s59;;d62;s62;s62;s62;s66;s64;s65;s67;d-70;s71;d-72;d+67s73;s68;d+68;s76;d-77;d-75s78;;s80;d-81;d+69s82;s69d-80;s72;s85;s85;;d88;s88;s88;s88;s92;s90;s91;s93;d-96;s97;d-98;d+93s99;s94;d+94;s102;d-103;d-101s104;;s106;d-107;d+95s108;s95d-106;/rC:-.3752,1.4197,0;-1.7087,2.1897,0;.3948,2.7534,0;-1.1452,.0861,0;.9586,.6497,0;.9586,-.8903,0;1.9348,2.7534,0;-2.6852,.0861,0;-.375,-1.6603,0;-.375,-3.2003,0;.9586,-3.9703,0;2.2923,-3.2003,0;2.2923,-1.6603,0;2.7048,4.0871,0;2.705,1.4197,0;4.245,1.4197,0;5.0148,2.7534,0;4.2448,4.0871,0;-4.9952,1.4198,0;-5.7652,.0861,0;-4.995,-1.2476,0;-3.455,-1.2476,0;-3.4552,1.4197,0;6.5548,2.7534,0;7.3248,1.4197,0;7.3248,4.0869,0;-7.3052,.0861,0;-8.0752,-1.2476,0;-8.0752,1.4198,0;.9586,-5.5103,0;2.2923,-6.2803,0;-.3752,-6.2803,0;16.6748,1.4286,0;15.3412,2.1986,0;17.4448,2.7624,0;15.9048,.0949,0;18.0085,.6586,0;18.0085,-.8814,0;18.9848,2.7624,0;14.3648,.0949,0;16.6748,-1.6514,0;16.6748,-3.1914,0;18.0085,-3.9614,0;19.3422,-3.1914,0;19.3422,-1.6514,0;19.7548,4.0959,0;19.7548,1.4286,0;21.2948,1.4286,0;22.0648,2.7622,0;21.2948,4.0959,0;12.0548,1.4286,0;11.2848,.0951,0;12.0548,-1.2387,0;13.5948,-1.2388,0;13.5948,1.4286,0;23.6048,2.7622,0;24.3748,1.4286,0;24.3748,4.0959,0;18.0085,-5.5014,0;19.3422,-6.2714,0;16.6748,-6.2714,0;-.4617,-12.0278,0;-1.7954,-11.2578,0;.3083,-10.694,0;-1.2317,-13.3613,0;.872,-12.7978,0;.872,-14.3378,0;1.8483,-10.694,0;-2.7717,-13.3613,0;-.4617,-15.1078,0;-.4617,-16.6478,0;.872,-17.4178,0;2.2056,-16.6478,0;2.2056,-15.1078,0;2.6183,-9.3603,0;2.6183,-12.0278,0;4.1583,-12.0278,0;4.9283,-10.694,0;4.1583,-9.3603,0;-5.0817,-12.0276,0;-5.8517,-13.3613,0;-5.0817,-14.695,0;-3.5417,-14.695,0;-3.5417,-12.0276,0;.872,-18.9578,0;2.2056,-19.7278,0;-.4617,-19.7278,0;14.2783,-12.7707,0;12.9446,-12.0007,0;15.0483,-11.437,0;13.5083,-14.1044,0;15.6118,-13.5407,0;15.6118,-15.0807,0;16.5883,-11.437,0;11.9683,-14.1044,0;14.2783,-15.8507,0;14.2783,-17.3907,0;15.6118,-18.1607,0;16.9456,-17.3907,0;16.9456,-15.8507,0;17.3583,-10.1032,0;17.3583,-12.7707,0;18.8983,-12.7707,0;19.6683,-11.437,0;18.8983,-10.1034,0;9.6583,-12.7707,0;8.8883,-14.1043,0;9.6583,-15.438,0;11.1983,-15.438,0;11.1983,-12.7707,0;
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
9
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance is very toxic to aquatic life with long lasting effects, is suspected of damaging fertility or the unborn child and may cause damage to organs through prolonged or repeated exposure.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance may cause an allergic skin reaction.

Breakdown of all 869 C&L notifications submitted to ECHA

Repr. 2 H361
STOT RE 2 H373
Skin Sens. 1 H317
Aquatic Chronic 2 H411
Aquatic Chronic 1 H410
Aquatic Chronic 4 H413
Not Classified
Aquatic Acute 1 H400
Skin Sens. 1B H317
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 5 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases, coating products, adhesives and sealants, polymers, photo-chemicals and hydraulic fluids.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and rubber (e.g. tyres, shoes, toys).

This substance is used in the following products: polymers, hydraulic fluids, metal working fluids, lubricants and greases, adhesives and sealants, coating products and photo-chemicals.

This substance is used in the following areas: formulation of mixtures and/or re-packaging, scientific research and development, building & construction work and printing and recorded media reproduction. This substance is used for the manufacture of: plastic products, textile, leather or fur, wood and wood products and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, roller or brushing applications, hand mixing with intimate contact only with personal protective equipment available, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, non-industrial spraying, treatment of articles by dipping and pouring and industrial spraying.

Release to the environment of this substance can occur from industrial use: in the production of articles, formulation of mixtures and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following products: lubricants and greases, metal working fluids, coating products, hydraulic fluids, polymers, adhesives and sealants, laboratory chemicals and photo-chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, mixing in open batch processes, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: lubricants and greases, polymers, coating products, heat transfer fluids, laboratory chemicals, adhesives and sealants, photo-chemicals and hydraulic fluids.

This substance is used in the following areas: scientific research and development, formulation of mixtures and/or re-packaging, building & construction work and printing and recorded media reproduction. This substance is used for the manufacture of: textile, leather or fur, wood and wood products and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, treatment of articles by dipping and pouring, industrial spraying, roller or brushing applications and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: in the production of articles, in processing aids at industrial sites, formulation of mixtures, formulation in materials and of substances in closed systems with minimal release. Other release to the environment of this substance is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; obtain special instructions before use; use personal protective equipment as required.; avoid release to the environment.

Response statements

In case of incident: If exposed or concerned: get medical advice/attention. Get medical advice/attention if you feel unwell. Collect spillage.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Everkem Srl, Via Melchiorre Gioia, 168 20125 Milano Italy
  • ICL-IP Bitterfeld GmbH, Rudolph-Glauber-Strasse 7 06749 Bitterfeld Germany
  • LANXESS SOLUTIONS UK LTD, Tenax Road M17 1WT Manchester United Kingdom
  • PCC Rokita SA, Sienkiewicza 4 56-120 Brzeg Dolny Poland

Other names

  • -
  • diphenyl 4-(propan-2-yl)phenyl phosphate phenyl bis[4-(propan-2-yl)phenyl] phosphate triphenyl phosphate tris[4-(propan-2-yl)phenyl] phosphate
  • IpTPP
  • Isopropylated phenol phosphate
  • Isopropylated Triaryl Phosphate
  • isopropylated triphenyl phosphate
  • Isopropylphenyl phosphate
  • Phenol, isopropalyted, phosphate
  • Phenol, isopropylated, phosphate (3:1)
  • phenol, isopropylated, phosphate (3:1) [Triphenyl phosphate >5%]
  • tris(4-isopropylphenyl) phosphate
  • tris(isopropylphenyl) phosphate
  • Phenol, isopropylated, phosphate (3:1)
  • Durad®
  • Lubad®
  • Phosflex 31L
  • Phosflex 41L
  • Reofos®
  • Reolube®
  • Roflex
  • Syn-o-ad 9578

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Viscous (100%) [1]
C Odour
Odourless (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-20 °C

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
400 °C @ 98 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
400 °C

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
1.168 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.168

Vapour pressure

Study results
  • 3 studies submitted
  • 2 studies processed
R Vapour pressure
0 - 0 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 1 study submitted
  • 1 study processed
R Pow
85 000 - 150 000 [1]
R Log Pow
4.92 - 5.17 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
4.92 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
330 - 367 µg/L @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
330 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
200 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
200 °C

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Non-explosive (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
37.8 - 96.3 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
96.3 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life for hydrolysis
18.5 days @ 25 °C

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Under test conditions no biodegradation observed (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
776 L/kg ww

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
8 511

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 310 ng/L (1)
Intermittent releases (freshwater) 15 µg/L (1)
Marine water 31 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 185 µg/kg sediment dw (1)
Sediment (marine water) 18.5 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 2.5 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 1.85 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 5 studies submitted
  • 4 studies processed
P/RResults
LC50 (4 days) 1.6 - 50.1 mg/L [4]
NOEC (4 days) 560 - 5 600 µg/L [4]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
10.8 mg/L

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (33 days) 3.1 µg/L [1]
LOEC (33 days) 8.2 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
3.1 µg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
LC50 (48 h) 1.5 - 1 000 mg/L [3]
NOEC (48 h) 560 - 1 000 000 µg/L [4]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
1.5 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 41.5 µg/L [1]
LOEC (21 days) 106 µg/L [1]
EC50 (21 days) 150 - 198 µg/L [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
41.5 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 2.5 mg/L [3]
EC50 (72 h) 2.5 - 1 000 mg/L [4]
NOEC (4 days) 310 - 1 300 µg/L [3]
NOEC (72 h) 310 µg/L [3]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
2.5 mg/L
EC10 or NOEC for freshwater algae
2.5 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 1 g/L [1]
NOEC (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
1 g/L
EC10 or NOEC for microorganisms
1 g/L

Sediment toxicity

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (28 days) 37 mg/kg sediment dw [1]
LOEC (28 days) 37 mg/kg sediment dw [1]
EC50 (28 days) 87 mg/kg sediment dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater sediment
87 mg/kg sediment dw
EC10 / LC10 or NOEC for freshwater sediment
37 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (56 days) 250 - 1 000 mg/kg soil dw [2]
NOEC (14 days) 500 mg/kg soil dw [1]
EC50 (56 days) 1 g/kg soil dw [1]
LC50 (14 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg soil dw
Long-term EC10 / LC10 / NOEC
250 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (19 days) 100 mg/kg soil dw [2]
LC50 (18 days) 100 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
100 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50
1.01 g/kg soil dw
Long-term EC10 / NOEC
582.7 mg/kg soil dw

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 145 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 700 mg/m³ acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 416.5 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 2 000 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 16 mg/cm² skin irritation/corrosion
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: (DNEL) 350 mg/m³ acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 208 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 100 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 8 mg/cm² skin irritation/corrosion
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 40 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 50 mg/kg bw/day acute toxicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 50 %
Dermal: 10 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (60 min) 200 mg/L air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 10 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 200 mg/m³
Dermal route:
No adverse effect observed LD50 10 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 1 2
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 25 mg/kg bw/day [3]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 25 mg/kg bw/day (subchronic, rat)
Dermal route - systemic effects:
Adverse effect observed NOAEL 100 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
Adverse effect observed NOAEC 10 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
Adverse effect observed NOAEL 25 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 200 mg/kg bw/day (subacute, rat)

Neurotoxicity

Study results
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 17
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed NOAEL 20 mg/kg bw/day (subchronic, hen)
Dermal route:
No adverse effect observed NOAEL 50 mg/kg bw/day (subchronic, hen)
Inhalation route:
Adverse effect observed NOAEC 620 µg/m³ (subacute, hen)

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant