Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
270-695-5
CAS no.:
68476-55-1
Index number:
649-402-00-3
Molecular formula:
C5H12
SMILES:
CCC(C)C
InChI:
InChI=1S/C5H12/c1-4-5(2)3/h5H,4H2,1-3H3
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
32
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is very toxic to aquatic life with long lasting effects, causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life, is toxic if swallowed, is toxic in contact with skin, is toxic if inhaled, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes serious eye irritation, is suspected of causing cancer, causes skin irritation, may cause drowsiness or dizziness and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is toxic to aquatic life with long lasting effects, is a highly flammable liquid and vapour and may cause damage to organs through prolonged or repeated exposure.

Breakdown of all 438 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
STOT SE 3 H336
Aquatic Chronic 2 H411
Skin Irrit. 2 H315
Carc. 1B H350 Harmonised Classification
Repr. 2 H361
Flam. Liq. 2 H225
Carc. 1A H350
Flam. Liq. 1 H224
STOT RE 2 H373
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Eye Irrit. 2 H319
STOT RE 1 H372
https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (92.96% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (91.11% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 26 active registrations under REACH, 3 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, of substances in closed systems with minimal release, formulation of mixtures and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use non-sparking tools; ground and bond container and receiving equipment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid release to the environment; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; use explosion-proof equipment (electrical/ventilating/lighting/etc.); keep container tightly closed; avoid breathing the dust, fume, gas, mist, vapours or spray; take actions to prevent static discharges; do not eat, drink or smoke when using this product; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If eye irritation persists get medical advice/attention. Take off contaminated clothing and wash it before reuse. Call a poison center or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. If skin irritation occurs: Get medical advice/attention. Do not induce vomiting. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If exposed or concerned: get medical advice/attention. Collect spillage. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Follow specific treatment (see label).

Storage statements

Store this substance in a well-ventilated place and Keeping it cool; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Basell Polyoléfines France SAS, Chemin Departemental 21 A 13130 Berre l'Etang France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BAYERNOIL Raffineriegesellschaft mbH, Raffineriestr. 100 93333 Neustadt Bavaria Germany
  • BP Europa SE, Überseeallee 1 20457 Hamburg Germany
  • BP Oil España S.A. Unipersonal, Avenida de Barajas 30 Parque Empresarial Omega - Edificio D 28108 Alcobendas Madrid Spain
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • Eastman Chemical Middelburg B.V., Herculesweg 35 4338PL Middelburg Netherlands
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • ISAB S.r.l., ex S.s. 114 km 146 96010 Priolo Gargallo (SR) Sicily Italy
  • LUKOIL Neftohim Burgas AD (Stavrolen), Western Industrial Zone 8104 Bourgas Bulgaria
  • Lyondell Chemie France S.A.S., Zone Industrielle Portuaire 13270 Fos sur Mer France
  • Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
  • OMV Downstream GmbH, Trabrennstraße 6-8 A-1020 Wien Austria
  • OMV PETROM S.A., 22 Coralilor Street (“Petrom City”) Sector 1 013329 Bucharest Romania
  • ORLEN Unipetrol RPA s.r.o., Litvinov - Zaluzi 1 43670 Litvinov Czech Republic
  • PCK RAFFINERIE GMBH, Passower Chaussee 111 16303 Schwedt/Oder Germany
  • PetroChina International (Netherlands) Company B.V, Vasteland 78 HNK Rotterdam Scheepvaartkwartier 3011BN Rotterdam Netherlands
  • Polski Koncern Naftowy ORLEN SA, ul. Chemików 7 09-411 Płock Poland
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • Ruhr Oel GmbH, Pawiker Strasse 30 45896 Gelsenkirchen Germany
  • SC Rompetrol Rafinare SA, Navodari Street no.215, Administrative Building 905700 Navodari Constanta Romania
  • Shell Chemicals Europe B.V., Weena 70 3012 CM Rotterdam Netherlands
  • Shell Nederland Chemie B.V., Chemieweg 25 PO BOX 6060, 4780 LN Moerdijk Netherlands
  • Synthomer Trading Limited Dutch Branch, IJsselstraat 41 5437KG Oss Netherlands
  • LUKOIL Neftohim Burgas AD (KNH), Western Industrial Zone 8104 Bourgas Bulgaria
  • versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy

Substance names and other identifiers

Hydrocarbons, C5-rich
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Hydrocarbons, C5-rich
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Hydrocarbons, C5-rich; Low boiling point naphtha — unspecified
Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Low boiling point naphtha - unspecified
C&L Inventory
.sb.Nafta z nizkim vreliščem – neopredeljeno (sl)
C&L Inventory
Alacsony forráspontú benzin – nem meghatározott (hu)
C&L Inventory
Angliavandeniliai, turi daug C5 (lt)
C&L Inventory
carbonhydrider, C5-rige (da)
C&L Inventory
Fracţia nafta cu punct de fierbere scăzut – nespecificat (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere scăzut – nespecificat (ro)
C&L Inventory
Hidrocarbonetos, ricos em C5 (pt)
C&L Inventory
Hidrocarburi bogate în C5 (mt)
C&L Inventory
Hidrocarburi bogate în C5 (ro)
C&L Inventory
hidrocarburos, ricos en C5 (es)
C&L Inventory
Hiilivedyt, C5-rikas (fi)
C&L Inventory
Hydrocarbures riches en C5;naphta à bas point d'ébullition — non spécifié; (fr)
C&L Inventory
hydrokarboner, C5-rike (no)
C&L Inventory
idrocarburi, arricchiti in C5 (it)
C&L Inventory
Kohlenwasserstoffe, C5-reich (de)
C&L Inventory
Kolväten, C5-rika (sv)
C&L Inventory
Koolwaterstoffen, rijk aan C5 (nl)
C&L Inventory
Lavtkogende uspecificeret nafta (da)
C&L Inventory
lavtkokende nafta - uspesifisert (no)
C&L Inventory
Ligroīns ar zemu viršanas temperatūru – nestandarta (lv)
C&L Inventory
Lågkokande nafta – ospecificerad (sv)
C&L Inventory
Madala keemispunktiga raskbensiin – määratlemata (et)
C&L Inventory
Matalalla kiehuva teollisuusbensiini – täsmentämätön (fi)
C&L Inventory
nafta con basso punto di ebollizione - non specificata (it)
C&L Inventory
Nafta de baixo ponto de ebulição - não especificada (pt)
C&L Inventory
nafta de bajo punto de ebullición, sin especificar (es)
C&L Inventory
Nafta met laag kookpunt - niet gespecifieerd (nl)
C&L Inventory
naphta à point d'ébullition bas - non spécifié (fr)
C&L Inventory
Naphtha, niedrigsiedend, nicht spezifiziert (de)
C&L Inventory
Nisko-vrijući benzin - nespecificiran (hr)
C&L Inventory
Niskowrząca benzyna - niespecyfikowana (pl)
C&L Inventory
Nízkovroucí benzínová frakce – nespecifikovaná (cs)
C&L Inventory
ogljikovodiki, pretežno C.sb.5 (sl)
C&L Inventory
Ogļūdeņraži, bagāti ar C5 (lv)
C&L Inventory
Szénhidrogének, C5-ben gazdag (hu)
C&L Inventory
Süsivesinikud, C5–6-rikas (et)
C&L Inventory
Ugljikovodici, s pretežito C5 (hr)
C&L Inventory
Uhlovodíky, bohaté na C5; (cs)
C&L Inventory
uhľovodíky, s vysokým obsahom C5 (sk)
C&L Inventory
Węglowodory bogate w C5 (pl)
C&L Inventory
ťažký benzín s nízkou teplotou varu - nešpecifikovaný (sk)
C&L Inventory
Žematemperatūris pirminis benzinas – neapibrėžtas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως - μη προσδιοριζόμενη (el)
C&L Inventory
υδρογονάνθρακεςΥδρογονάνθρακες, πλούσιοι σε C5 (el)
C&L Inventory
Въглеводороди, богати на C5 (bg)
C&L Inventory
Нискооктанов бензин с ниска температура на кипене-неспецифициран (bg)
C&L Inventory
Hydrocarbons, C5-rich
Other
Hydrocarbons C5-rich
Registration dossier
Hydrocarbons, C5-rich
C&L Inventory, Registration dossier
Hydrocarbons, C5-rich
Registration dossier
IP feed
Registration dossier
Light Naphtha
Registration dossier
Taglio C5, Pentani
Registration dossier
C5 Dienes crude
Registration dossier
649-402-00-3
Index number
C&L Inventory
68476-55-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 15 studies submitted
  • 15 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [15]
C Form
Other (100%) [2]
C Odour
Other (57%), Faint (21%), Characteristic of aromatic compounds (14%), Slight (7%) [14]
C Substance type
Organic (67%), Petroleum product (33%) [15]

Type of Study provided
Studies with data
Key study 10 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 9 studies submitted
  • 9 studies processed
R Melting / freezing point
-140 - -50 °C @ 101.3 kPa [9]

Type of Study provided
Studies with data
Key study 7 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
-100 - 5.49 °C

Boiling point

Study results
  • 21 studies submitted
  • 18 studies processed
R Boiling point
-20 - 260 °C @ 10.133 - 1 013.25 hPa [18]

Type of Study provided
Studies with data
Key study 14 4
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
46.25 - 80.09 °C

Density

Study results
  • 12 studies submitted
  • 11 studies processed
R Density
0.692 - 0.734 g/cm³ @ 15 - 20 °C [6]
R Relative density
0.62 - 0.88 @ 15 - 20 °C [7]

Type of Study provided
Studies with data
Key study 12
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.718 - 0.876

Vapour pressure

Study results
  • 17 studies submitted
  • 13 studies processed
R Vapour pressure
56.2 - 2 400 hPa @ 20 - 100.1 °C [35]

Type of Study provided
Studies with data
Key study 12 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 3 summaries processed
Vapour pressure
99.5 - 470.7 hPa @ 20 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 8 studies processed
R Log Pow
2.13 - 6.1 @ 21 - 23 °C and pH 6.2 - 7 [8]

Type of Study provided
Studies with data
Key study 7 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
2.13 - 3.2 @ 20 °C

Water solubility

Study results
  • 9 studies submitted
  • 6 studies processed
R Water solubility (mass/vol.)
52 - 718 mg/L @ 20 °C and pH 6.1 - 9.2 [8]

Type of Study provided
Studies with data
Key study 6 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 5 summaries submitted
  • 3 summaries processed
Water solubility
60.6 - 1 880 mg/L @ 20 - 23.5 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Surface tension at 20 °C
71.6 mN/m @ 198 mg/L

Flash point

Study results
  • 6 studies submitted
  • 6 studies processed
R Flash point
-40 - -24 °C @ 101.3 - 102.6 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
-40 - -27 °C

Auto flammability

Study results
  • 9 studies submitted
  • 6 studies processed
R Autoflammability / self-ignition
258 - 470 °C @ 99.5 - 102.5 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Autoflammability / self-ignition at 101 325 Pa
293 - 315 °C

Flammability

Study results
  • 7 studies submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 2
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 2
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 13 studies submitted
  • 12 studies processed
R dynamic viscosity (in mPa s)
0.32 - 0.47 [12]
R kinematic viscosity (in mm²/s)
0.47 - 1 [18]

Type of Study provided
Studies with data
Key study 11 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Static viscosity at 20 °C
0.51 - 0.6 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
80.64 - 8 467.2 min [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 2 3
Supporting study 8 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 4 summaries submitted
  • 2 summaries processed
Biodegradation in water
Readily biodegradable (50%), Inherently biodegradable (50%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 5 studies submitted
  • 1 study processed
R log Koc
1.5 - 4.04 dimensionless [2]

Type of Study provided
Studies with data
Key study 4 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 4 summaries submitted
  • 3 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (3)
Intermittent releases (freshwater) No data available: testing technically not feasible (3)
Marine water No data available: testing technically not feasible (3)
Intermittent releases (marine water) No data available: testing technically not feasible (3)
Sewage treatment plant (STP) No data available: testing technically not feasible (3)
Sediment (freshwater) No data available: testing technically not feasible (3)
Sediment (marine water) No data available: testing technically not feasible (3)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (3)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 24 studies submitted
  • 9 studies processed
P/RResults
LC50 (4 days) 8.41 mg/L [2]
LL50 (4 days) 8.2 - 27.9 mg/L [7]

Type of Study provided
Studies with data
Key study 4
Supporting study 14 1
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 9 studies submitted
  • 6 studies processed
P/RResults
EL10 (60 days) 2.12 - 5.35 mg/L [5]
EL50 (21 days) 10 mg/L [1]
NOELR (21 days) 2.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence 5
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 20 studies submitted
  • 8 studies processed
P/RResults
EC50 (48 h) 4.7 mg/L [2]
EL50 (48 h) 4.5 - 48.7 mg/L [6]
NOELR (48 h) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 11 1
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 6 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [2]
EL10 (21 days) 3.69 - 9.34 mg/L [5]
EL50 (21 days) 10 - 40 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence 5
Other 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 26 studies submitted
  • 10 studies processed
P/RResults
EC50 (72 h) 12.4 - 18.9 mg/L [4]
NOEC (72 h) 6.47 mg/L [4]
EL10 (72 h) 1.56 - 17 mg/L [9]
EL50 (4 days) 3.7 mg/L [1]
EL50 (72 h) 3.1 - 41 mg/L [10]

Type of Study provided
Studies with data
Key study 5 1
Supporting study 15 1
Weight of evidence 4
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 8 studies submitted
  • 1 study processed
P/RResults
EC50 (40 h) 15.41 mg/L [1]

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 11 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 5
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 4
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 7 studies submitted
  • 5 studies processed
P/RResults
other: (28 days) 13.1 - 86.5 mg/kg soil dw [10]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 5
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 11 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 5
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 4
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 5
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 7 summaries submitted
  • 7 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 837.5 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 066.67 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 11 mg/kg bw/day neurotoxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 140 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 178.57 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 640 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5.3 mg/kg bw/day neurotoxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 213 µg/kg bw/day -
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
EYE Exposure
Hazard unknown (no further information necessary as no exposure expected)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 25 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 7 1
Supporting study 12 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Study data: dermal absorption
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 5 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 50 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 66 studies submitted
  • 22 studies processed
P/RResults
LD50 512 - 6 631 mg/kg bw (rat) [23]
LD50 1 - 4 mL/kg bw (rat) [2]
LD50 5 251 - 5 627 mg/kg bw (mouse) [4]
M/CInterpretations of results
Category 5 based on GHS criteria [2]

Type of Study provided
oral
Studies with data
Key study 16 6
Supporting study 4 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 76 studies submitted
  • 19 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.2 - 43.767 mg/L air (rat) [16]
LC50 (4 h) 5 540 - 13 700 ppm (rat) [11]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [3]

inhalation
Studies with data
Key study 17 5
Supporting study 12 38
Weight of evidence 4
Other
Data waiving
no waivers
dermal
  • 61 studies submitted
  • 17 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 3.03 mL/kg bw (rat) [2]
LD50 1 183 - 12 126 mg/kg bw (rabbit) [9]
LD50 1.59 - 5 mL/kg bw (rabbit) [3]
M/CInterpretations of results
Practically nontoxic [6]

dermal
Studies with data
Key study 11 4
Supporting study 43
Weight of evidence 3
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 5 summaries submitted
  • 3 summaries processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5.61 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 115 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 7 5
Supporting study 8 90
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 63 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 7 2
Supporting study 4 45
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 5 summaries submitted
  • 4 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 55 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4 3
Supporting study 2 42
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 5 summaries submitted
  • 5 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 21 studies submitted
  • 13 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [14]
NOAEL (mouse): 625 mg/kg bw/day [2]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [9]
LOAEL (mouse): 1 250 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 9 5
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Study data: inhalation
  • 62 studies submitted
  • 35 studies processed
P/RResults
NOAEC (rat): 96 - 19 503 mg/m³ air [13]
NOAEC (rat): 30 - 7 000 ppm [23]
NOAEC (mouse): 28 - 613 mg/m³ air [6]
NOAEC (mouse): 5 - 2 000 ppm [5]
NOAEC (other:): 1.402 mg/L air [1]

Study data: inhalation
Studies with data
Key study 29 8
Supporting study 4 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 52 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 49
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 1
M/C Summaries
  • 5 summaries submitted
  • 3 summaries processed
Oral route - systemic effects:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 71 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 38 10
Supporting study 4 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 60 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 27 12
Supporting study 6 15
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 5 summaries submitted
  • 3 summaries processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 38 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 16 10
Supporting study 2 8
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 5 summaries submitted
  • 3 summaries processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 25 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 14 2
Supporting study 3 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Study data: developmental
  • 47 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 29 5
Supporting study 1 6
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 4
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 5 summaries submitted
  • 2 summaries processed
Effect on fertility
Oral route:
No adverse effect observed LOAEL 50 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant