Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
265-086-6
CAS no.:
64741-84-0
Index number:
649-278-00-0
Molecular formula:
C26H60
SMILES:
CCCC(C)C.CCC(C)CC.CCCC(C)CC.CCC(C)C(C)C
InChI:
InChI=1/2C7H16.2C6H14/c1-5-7(4)6(2)3;1-4-6-7(3)5-2;1-4-5-6(2)3;1-4-6(3)5-2/h6-7H,5H2,1-4H3;7H,4-6H2,1-3H3;2*6H,4-5H2,1-3H3
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
28
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is very toxic to aquatic life with long lasting effects, causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life, is toxic in contact with skin, is toxic if inhaled, is toxic if swallowed, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes serious eye irritation, causes skin irritation, may cause drowsiness or dizziness, may cause respiratory irritation and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is a highly flammable liquid and vapour.

Breakdown of all 603 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Skin Irrit. 2 H315
STOT SE 3 H336
Repr. 2 H361
Flam. Liq. 2 H225
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
STOT RE 1 H372
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Flam. Liq. 1 H224
STOT RE 2 H373
Carc. 1A H350
https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (49.57% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (49.57% of REACH registrations).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (5.22% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 17 active registrations under REACH, 3 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, as processing aid and of substances in closed systems with minimal release.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, as processing aid, for thermoplastic manufacture, in the production of articles and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, laboratory work and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; obtain special instructions before use; do not eat, drink or smoke when using this product; avoid release to the environment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Wash contaminated clothing before reuse. If swallowed: immediately call a poison center or doctor/physician. If exposed or concerned: get medical advice/attention. If skin irritation occurs: Get medical advice/attention. Get medical advice/attention if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Collect spillage. If swallowed: rinse mouth. Do not induce vomiting. If inhaled: call a poison center or doctor/physician if you feel unwell. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention. Rinse the mouth. Do not induce vomiting. If swallowed: call a poison center or doctor/physician if you feel unwell. Follow specific treatment (see label).

Storage statements

Store this substance in a dry place; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • BP Europa SE, Überseeallee 1 20457 Hamburg Germany
  • Chemical Standards SIA, Ritausma 31 LV-2127 Medemciems Olaine parish Latvia
  • COMPANÍA ESPAÑOLA DE PETRÓLEOS, S.A.U. (CEPSA), Torre Cepsa, Paseo de la Castellana 259A 28046 Madrid Spain
  • ExxonMobil Chemical Holland B.V., Botlekweg, 121, Haven nr 40-60 NL 3197 KA Botlek Rotterdam Netherlands
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • MOL Hungarian Oil and Gas Public Limited Company, Oktober huszonharmadika 18 1117 Budapest Hungary
  • PCK RAFFINERIE GMBH, Passower Chaussee 111 16303 Schwedt/Oder Germany
  • Petroineos Manufacturing France SAS, Avenue de la Bienfaisance BP 6 133117 Lavera France
  • Petróleos de Portugal - Petrogal, S.A., Rua Tomás da Fonseca, Torres de Lisboa, Torre C 1600-209 Lisboa Portugal
  • Ruhr Oel GmbH, Pawiker Strasse 30 45896 Gelsenkirchen Germany
  • SARLUX srl, S.S. Sulcitana 195 km. 19 09018 Sarroch (CA) Sardinia Italy
  • SC Rompetrol Rafinare SA, Navodari Street no.215, Administrative Building 905700 Navodari Constanta Romania
  • Shell Chemicals Europe B.V., Weena 70 3012 CM Rotterdam Netherlands
  • Shell Nederland Chemie B.V., Chemieweg 25 PO BOX 6060, 4780 LN Moerdijk Netherlands
  • Shell Trading Rotterdam B. V., Weena 70 3012 CM Rotterdam Netherlands
  • SLOVNAFT, a.s., Vlcie hrdlo 1 824 12 Bratislava Slovakia
  • versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • SABIC UK Petrochemicals Limited, Wilton Centre TS10 4RF Redcar Cleveland United Kingdom
  • Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
  • Steptoe & Johnson LLP, Av Louise, 489 1050 Brussels Belgium
  • VPR Energy BV, Neckarweg 5 Haven 5526 3198 Rotterdam Netherlands

Substance names and other identifiers

[A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).]
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory
Low boiling point modified naphtha
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory
Naphtha (petroleum), solvent-refined light
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), solvent-refined light
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), solvent-refined light; Low boiling point modified naphtha [ complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approxi mately 35 °C to 190 °C (95°F to 374°F).]
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), solvent-refined light; Low boiling point modified naphtha
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
Naphtha, petroleum, solvent-refined light
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
Other
Solvent refined light naphtha heartcut (petroleum)
A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon numbers predominantly in the range of C5 through C11 and boiling in the range of approximately 35°C to 190°C (95°F to 374°F).
Other
(Keerulise koostisega süsivesinike segu, mis saadakse rafinaadina lahusti-ekstraktsioonprotsessist. Koosneb peamiselt alifaatsetest süsivesinikest, valdavalt C5 kuni C11, ning on keemistemperatuuriga umbes 35°C kuni 190 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven kao rafinat u postupku ekstrakcije otapalom. Sastoji se pretežito od alifatskih ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C5 do C11 i vriju u području približno od 35 ºC do 190 ºC.) (hr)
C&L Inventory
[(Složitá směs uhlovodíků získaná jako rafinát při rozpouštědlovém extrakčním procesu. Je složena převážně z alifatických uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C5 až C11 a s rozmezím teploty varu přibližně 35 °C až 190 °C.] (cs)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet som raffinat fra en løsemiddelekstraksjon (solventekstraksjon). Består for det meste av alifatiske hydrokarboner, hovedsakelig C5 til C11, med omtrentlig kokepunktsintervall fra 35 °C til 190 °C (95 °F til 374 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena kot rafinat iz procesa solventne ekstrakcije. Sestoji pretežno iz alifatskih ogljikovodikov s številom ogljikovih atomov v območju med C5 in C11 ter z vreliščem v območju približno med 35 °C in 190 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten als Raffinat aus der Lösungsmittelextraktion; besteht vorwiegend aus aliphatischen Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C5 bis C11 mit einem Siedebereich von etwa 35 °C bis 190 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná v podobe rafinátu z extrakcie rozpúšťadlom. Pozostáva predovšetkým z alifatických uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C5 do C11. Má teplotu varu v rozmedzí približne od 35 °C do 190 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută ca produs de rafinare printr-un proces de extracţie cu solvent. Constă predominant în hidrocarburi alifatice având un număr de atomi de carbon cuprins între C5 şi C11 şi al căror punct de fierbere este cuprins între aproximativ 35°C şi 190°C (95°F şi 374°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts kā rafināts ekstrakcijas procesā ar šķīdinātāju. Sastāv pārsvarā no alifātiskiem ogļūdeņražiem, pārsvarā ar oglekļa atomu skaitu no C5 līdz C11, aptuvenā viršanas temperatūra no 35°C līdz 190°C (95°F līdz 374°F).] (lv)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas kaip ekstrahavimo tirpikliais proceso rafinatas. Jį sudaro daugiausia sotieji angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C5 iki C11, ir kurių virimo temperatūra maždaug nuo 35 °C iki 190 °C (nuo 95 °F iki 374 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet oldószeres extrakciós folyamatokból raffinátumként nyernek. Főleg olyan alifás szénhidrogénekből áll, melyek szénatomszáma főleg a C5-C11 tartományban, forráspontja kb. a 35°C-tól 190°C-ig (95°F-től 374°F-ig) terjedő tartományban van.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται ως το εξευγενισμένο πετρελαιοειδές από διεργασία εκχύλισης με διαλύτη. Συνίσταται κυρίως από αλειφατικούς υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύC5 και C11 που αποστάζουν μεταξύ 35 °C και 190 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена като рафинат при екстракционен процес с разтворител. Състои се основно от наситени въглеводороди с разклонена верига с брой на въглеродните атоми преобладаващо в интервала от C5 от C11 включително и с температура на кипене приблизително в интервала от 35°C до 190°C (95°F до 374°F).] (bg)
C&L Inventory
Alacsony forráspontú módosított benzin (hu)
C&L Inventory
Benzin (nafta), otapalom rafiniran laki (hr)
C&L Inventory
Benzin (nyersolaj), oldószerrel finomított könnyű (hu)
C&L Inventory
Benzyna lekka, rafinowana rozpuszczalnikiem (ropa naftowa) (pl)
C&L Inventory
Benzínová frakce (ropná), rozpouštědlově rafinovaná lehká (cs)
C&L Inventory
combinación compleja de hidrocarburos obtenida como refinado de un proceso de extracción con disolvente; compuesta principalmente de hidrocarburos alifáticos con un número de carbonos en su mayor parte dentro del intervalo de C5 a C11 y con un intervalo de ebullición aproximado de 35 °C a 190 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue comme raffinat lors d'une extraction au solvant. Se compose principalement d'hydrocarbures aliphatiques dont le nombre de carbones se situe en majorité dans la gamme C5-C11 et dont le point d'ébullition est compris approximativement entre 35°C et 190°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta come prodotto di raffinazione di un processo di estrazione con solvente. È costituita in prevalenza da idrocarburi alifatici con un numero di atomi di carbonio prevalentemente nell'intervallo C5-11 e punto di ebollizione nell'intervallo 35 °C - 190 °C ca. (da 95°F a 374°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida como refinado de um processo de extracção com solventes. É constituída predominantemente por hidrocarbonetos alifáticos com número de átomos de carbono predominantemente na gama C5 a C11 e destilação no intervalo aproximado de 35 °C a 190 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen als raffinaat van een oplosmiddelextractieproces. Bestaat voornamelijk uit alifatische koolwaterstoffen, overwegend C5 tot en met C11, met een kooktraject van ongeveer 35°C tot 190°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået som raffinatet fra en solventekstraktionsproces. Den består overvejende af aliphatiske carbonhydrider, overvejende C5 til og med C11, med kogeinterval omtrent fra 35 °C til 190 °C (95 ºF til 374 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), uşoară rafinare cu solvent (mt)
C&L Inventory
Fracţia nafta (petrol), uşoară rafinare cu solvent (ro)
C&L Inventory
Fracţia nafta modificată cu punct de fierbere la temperaturi scăzute (mt)
C&L Inventory
Fracţia nafta modificată cu punct de fierbere la temperaturi scăzute (ro)
C&L Inventory
Gemodificeerde nafta met laag kookpunt (nl)
C&L Inventory
Komplex blandning av kolväten erhållen som raffinat från en lösningsmedelsextraktion. Består främst av alifatiska kolväten, i synnerhet C5 till C11, med ungefärligt kokpunktsintervall från 35 °C till 190 °C. (sv)
C&L Inventory
Lavtkogende modificeret nafta (da)
C&L Inventory
lavtkokende modifisert nafta (no)
C&L Inventory
Ligroīns (nafta), vieglais, attīrīts ar šķīdinātājiem (lv)
C&L Inventory
Lågkokande modifierad nafta (sv)
C&L Inventory
Madala keemispunktiga modifitseeritud raskbensiin (et)
C&L Inventory
Matalalla kiehuva modifioitu teollisuusbensiini (fi)
C&L Inventory
Modificirana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Modifikovaná nízkovroucí benzínová frakce (cs)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu jalosteena liuotinuuttoprosessista. Koostuu pääasiassa alifaattisista hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C5:stä C11:een ja jotka kiehuvat likimäärin välillä 35°C:sta 190°C:seen (95°F:sta 374°F:iin). (fi)
C&L Inventory
Nafta (aardolie), oplosmiddelgeraffineerde lichte (nl)
C&L Inventory
Nafta (petroleum), lösningsmedelsraffinerad lätt (sv)
C&L Inventory
nafta (petroleum), solventraffinert lett (no)
C&L Inventory
nafta (petrolio), frazione leggera raffinata con solventi (it)
C&L Inventory
nafta (petróleo), fracción ligera refinada con disolvente (es)
C&L Inventory
Nafta (petróleo), fracção leve de refinação com solventes (pt)
C&L Inventory
Nafta (zemeljsko olje), s topilom rafinirana, lahka (sl)
C&L Inventory
Nafta modificada de baixo ponto de ebulição (pt)
C&L Inventory
nafta modificada de bajo punto de ebullición (es)
C&L Inventory
nafta modificata con basso punto di ebollizione (it)
C&L Inventory
Naphta léger (pétrole), raffiné au solvant;naphta modifié à bas point d'ébullition;[combinaison complexe d'hydrocarbures constituant le raffinat obtenu lors d'une extraction au solvant. Se compose principalement d'hydrocarbures aliphatiques comportant majoritairement entre 5 et 11 atomes de carbone (C5-C11) et dont l'intervalle d'ébullition est compris approximativement entre 35 et 190 oC (entre 95 et 374o F).] (fr)
C&L Inventory
naphta modifié à point d'ébullition bas (fr)
C&L Inventory
Naphtha (Erdöl), Lösungsmittelraffination, leicht (de)
C&L Inventory
naphtha (råolie), solventraffineret let (da)
C&L Inventory
Naphtha, niedrigsiedend, modifiziert (de)
C&L Inventory
Nisko-vrijući modificirani benzin (hr)
C&L Inventory
Niskowrząca modyfikowana frakcja benzynowa (pl)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută ca produs de rafinare printr-un proces de extracţie cu solvent. Constă predominant în hidrocarburi alifatice având un număr de atomi de carbon cuprins între C5 şi C11 şi al căror punct de fierbere este cuprins între aproximativ 35°C şi 190°C (95°F şi 374°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), tirpikliais valytas lengvasis (lt)
C&L Inventory
Raskbensiin (nafta), lahusti-rafineeritud, kerge (et)
C&L Inventory
Teollisuusbensiini (maaöljy), liuotinjalostettu kevyt (fi)
C&L Inventory
upravený benzín s nízkou teplotou varu (sk)
C&L Inventory
Zemā temperatūrā virstošs modificēts ligroīns (lv)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana jako rafinat z procesu ekstrakcji rozpuszczalnikiem. Składa się przede wszystkim z węglowodorów alifatycznych o liczbie atomów węgla głównie w zakresie od C5 do C11, wrzących w zakresie temp. od ok. 35°Cdo 190°C. (pl)
C&L Inventory
ťažký benzín (ropný), ľahký, rafinovaný rozpúšťadlom (sk)
C&L Inventory
Žematemperatūris modifikuotas pirminis benzinas (lt)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), ελαφρά, εξευγενισμένη με διαλύτη (el)
C&L Inventory
Τροποποιημένη νάφθα χαμηλού σημείου ζέσεως (el)
C&L Inventory
Модифициран нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
Нискооктанов бензин (нефт), рафиниран с разтворител, лек (bg)
C&L Inventory
Naphtha (petroleum), solvent-refined light
Other
2,3-dimethylpentane; 2-methylpentane; 3-methylhexane; 3-methylpentane
Other
[A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon number
C&L Inventory
[A complex combination of hydrocarbons obtained as the raffinate from a solvent extraction process. It consists predominantly of aliphatic hydrocarbons having carbon number .
C&L Inventory
C 6 Raffinate
Registration dossier
C6 Raffinate
Registration dossier
Low boiling point modified naphtha
C&L Inventory
Naphtha
C&L Inventory
NAPHTHA (PETROLEUM), SOLVENT-REFINED LIGHT
C&L Inventory, Registration dossier
Naphtha (petroleum), solvent-refined light
C&L Inventory, Registration dossier
Raffinate
Registration dossier
C7-Nichtaromaten
Registration dossier
C7-Nonaromatics
Registration dossier
Naphtha
Registration dossier
Naphtha (petroleum), solvent-refined light
C&L Inventory
Naphtha (petroleum), solvent-refined light; Low boiling point modified naphtha
C&L Inventory, Registration dossier
Not applicable
Registration dossier
Raffinate A1/2
Registration dossier
64741-84-0
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
649-278-00-0
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 36 studies submitted
  • 35 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [35]
C Form
Other (90%), Viscous (10%) [10]
C Odour
Characteristic of aromatic compounds (56%), Other (31%), Faint (9%) [32]
C Substance type
Petroleum product (52%), Organic (48%) [33]

Type of Study provided
Studies with data
Key study 15 20
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 6 summaries submitted
  • 6 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 14 studies submitted
  • 13 studies processed
R Melting / freezing point
-140 - -29 °C @ 101.3 kPa [15]

Type of Study provided
Studies with data
Key study 13
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Melting / freezing point at 101 325 Pa
-90 - 32.2 °C

Boiling point

Study results
  • 39 studies submitted
  • 30 studies processed
R Boiling point
-20 - 260 °C @ 100.7 - 101.33 kPa [32]

Type of Study provided
Studies with data
Key study 22 9
Supporting study 2 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Boiling point at 101 325 Pa
53 - 172.2 °C

Density

Study results
  • 24 studies submitted
  • 12 studies processed
R Density
0.72 g/cm³ @ 20 °C [2]
R Relative density
0.62 - 0.89 @ 15 - 20 °C [12]

Type of Study provided
Studies with data
Key study 17
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Relative density at 20°C
0.65 - 0.98

Vapour pressure

Study results
  • 43 studies submitted
  • 34 studies processed
R Vapour pressure
4 - 2 400 hPa @ 20 - 100.1 °C [64]

Type of Study provided
Studies with data
Key study 33 1
Supporting study 4 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Vapour pressure
1.86 - 302.7 hPa @ 2 - 20 °C

Partition coefficient

Study results
  • 17 studies submitted
  • 13 studies processed
R Log Pow
2.2 - 6.5 @ -248.15 - 25 °C and pH 6.2 - 7 [13]

Type of Study provided
Studies with data
Key study 13 1
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Log Kow (Log Pow)
2.13 - 5.84 @ 20 °C

Water solubility

Study results
  • 14 studies submitted
  • 12 studies processed
R Water solubility (mass/vol.)
25 - 600 mg/L @ 20 °C and pH 5.2 - 9.2 [13]
R Water solubility (vol%)
0.1 - 0.7 vol% @ 20 °C and pH 6.4 [2]

Type of Study provided
Studies with data
Key study 12 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 8 summaries submitted
  • 6 summaries processed
Water solubility
10 - 1 880 mg/L @ 20 - 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 13 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 12
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Surface tension at 20 °C
71.1 - 71.6 mN/m @ 198 - 243 mg/L

Flash point

Study results
  • 12 studies submitted
  • 12 studies processed
R Flash point
-40 - 43 °C @ 101.3 kPa [14]

Type of Study provided
Studies with data
Key study 12
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
-27 - 7.4 °C

Auto flammability

Study results
  • 15 studies submitted
  • 13 studies processed
R Autoflammability / self-ignition
258 - 502 °C @ 99.5 - 101.325 kPa [13]

Type of Study provided
Studies with data
Key study 12 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Autoflammability / self-ignition at 101 325 Pa
293 - 429 °C

Flammability

Study results
  • 5 studies submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 3
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 3
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 19 studies submitted
  • 17 studies processed
R dynamic viscosity (in mPa s)
0.32 - 0.95 [22]
R kinematic viscosity (in mm²/s)
0.47 - 1.5 [30]

Type of Study provided
Studies with data
Key study 16 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Static viscosity at 20 °C
0.6 mm²/s
Dynamic viscosity at 20 °C
0.723 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 19 studies submitted
  • 7 studies processed
C Interpretation of results
Readily biodegradable (100%) [7]

Type of Study provided
Studies with data
Key study 7 2
Supporting study 8 1
Weight of evidence 1
Other
Data waiving
no waivers
C Summaries
  • 8 summaries submitted
  • 6 summaries processed
Biodegradation in water
Readily biodegradable (50%), Under test conditions no biodegradation observed (50%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 5
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Bioaccumulation Factor (BCF) - dimensionless
98.2 - 1 112

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 1 summary processed
Koc at 20°C
824

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 5 summaries submitted
  • 4 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (3)
Intermittent releases (freshwater) No data available: testing technically not feasible (3)
Marine water No data available: testing technically not feasible (3)
Intermittent releases (marine water) No data available: testing technically not feasible (3)
Sewage treatment plant (STP) No data available: testing technically not feasible (3)
Sediment (freshwater) No data available: testing technically not feasible (3)
Sediment (marine water) No data available: testing technically not feasible (3)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (3)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 27 studies submitted
  • 10 studies processed
P/RResults
LC50 (4 days) 1 - 8.41 mg/L [8]
LL50 (4 days) 1.1 - 10 mg/L [3]

Type of Study provided
Studies with data
Key study 7 3
Supporting study 15 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 5 studies submitted
  • 1 study processed
P/RResults
EL50 (21 days) 10 mg/L [1]
NOELR (21 days) 2.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 23 studies submitted
  • 10 studies processed
P/RResults
EC50 (48 h) 900 - 10 000 µg/L [6]
EC50 (24 h) 10 mg/L [1]
IC50 (24 h) 1 - 4.7 mg/L [3]
LC50 (48 h) 3.78 mg/L [1]
EL50 (48 h) 1.2 - 4.5 mg/L [3]

Type of Study provided
Studies with data
Key study 7 3
Supporting study 11 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [2]
EL50 (21 days) 10 - 40 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 27 studies submitted
  • 10 studies processed
P/RResults
EC50 (4 days) 910 - 1 800 µg/L [4]
EC50 (73 h) 2.2 - 4.36 mg/L [2]
EC50 (72 h) 1.3 - 100 mg/L [11]
EC50 (3 h) 134 - 207 mg/L [2]
NOEC (4 days) 120 µg/L [1]

Type of Study provided
Studies with data
Key study 7 3
Supporting study 15 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 1 summary processed
EC50 for freshwater algae
1.6 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 5 studies submitted
  • 3 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [1]
EC50 (24 h) 84 mg/L [1]
IC50 (24 h) 13 mg/L [1]

Type of Study provided
Studies with data
Key study 3 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
2 mg/L

Sediment toxicity

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 5
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 5
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 3
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 9 summaries submitted
  • 9 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.9 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 286.4 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 2.31 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 160.23 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 950 µg/kg bw/day repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 410 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1 152 mg/m³ neurotoxicity
Local Effects
Long-term: (DNEL) 690 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 143.5 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/kg bw/day repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 30 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 25.6 mg/kg bw/day acute toxicity
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 20 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5 1
Supporting study 6 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other 1
Study data: dermal absorption
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 3 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 7 summaries submitted
  • 5 summaries processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 50 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 59 studies submitted
  • 17 studies processed
P/RResults
LD50 512 - 6 631 mg/kg bw (rat) [19]
LD50 5 251 - 5 627 mg/kg bw (mouse) [4]
M/CInterpretations of results
Practically nontoxic [2]

Type of Study provided
oral
Studies with data
Key study 12 5
Supporting study 2 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 56 studies submitted
  • 18 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.14 - 43.767 mg/L air (rat) [16]
LC50 (4 h) 5 922 - 13 700 ppm (rat) [11]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [2]

inhalation
Studies with data
Key study 12 6
Supporting study 38
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 57 studies submitted
  • 14 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 2 000 - 12 126 mg/kg bw (rabbit) [8]
LD50 5 000 mL/kg bw (rabbit) [1]
M/CInterpretations of results
Practically nontoxic [3]

dermal
Studies with data
Key study 8 5
Supporting study 43
Weight of evidence 1
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 7 summaries submitted
  • 6 summaries processed
Oral route:
Adverse effect observed LD50 590 mg/kg bw
Inhalation route:
Adverse effect observed LC50 1 972 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 107 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 10
Supporting study 3 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Study data: eye
  • 57 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3 4
Supporting study 45
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
M/C Summaries
  • 7 summaries submitted
  • 7 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 54 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4 3
Supporting study 1 42
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 7 summaries submitted
  • 7 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 23 studies submitted
  • 12 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [13]
NOAEL (mouse): 625 mg/kg bw/day [1]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [10]
LOAEL (mouse): 1 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 6 7
Supporting study 2 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Study data: inhalation
  • 46 studies submitted
  • 20 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [9]
NOAEC (rat): 30 - 7 000 ppm [19]
NOAEC (mouse): 32 - 96 mg/m³ air [2]
NOAEC (mouse): 5 - 2 000 ppm [5]
LOAEC (rat): 2.261 - 4.71 mg/L air [4]

Study data: inhalation
Studies with data
Key study 12 9
Supporting study 21
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Study data: dermal
  • 54 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study 1
Supporting study 49
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
M/C Summaries
  • 7 summaries submitted
  • 6 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 4 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)

Genetic toxicity

Study results
Study data: in vitro
  • 61 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 29 11
Supporting study 1 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: in vivo
  • 40 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 10 12
Supporting study 17
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 7 summaries submitted
  • 5 summaries processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 37 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 14 13
Supporting study 2 8
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 7 summaries submitted
  • 5 summaries processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 11 3
Supporting study 2 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Study data: developmental
  • 39 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 19 7
Supporting study 1 6
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 3
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 7 summaries submitted
  • 2 summaries processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 60 mg/kg bw/day (subacute, rat)
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4 5
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 4 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant