Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
244-492-7
CAS no.:
21645-51-2
Index number:
Molecular formula:
AlH3O3
SMILES:
[OH-].[OH-].[OH-].[Al+3]
InChI:
InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
31
Of which contain:
15 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye irritation, may cause respiratory irritation and causes skin irritation.

Breakdown of all 2213 C&L notifications submitted to ECHA

Not Classified
Eye Irrit. 2 H319
STOT SE 3 H335
Skin Irrit. 2 H315
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Aerosol 1 H222,H229
STOT SE 3 H336
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Nanomaterial form

Substance is known to be on the EEA market in nanomaterial form, as listed in the EUON Nanomaterials in the EU market list.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 114 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:
Nanomaterials in the EU Market

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: cosmetics and personal care products, coating products, inks and toners, fillers, putties, plasters, modelling clay and pharmaceuticals.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), the low energy manipulation of substances bound in materials or articles, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting) and open transfer and processing with minerals/metals at elevated temperature.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance can be found in complex articles, with no release intended: electrical batteries and accumulators, vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), rubber (e.g. tyres, shoes, toys) and leather (e.g. gloves, shoes, purses, furniture).

This substance is used in the following products: inks and toners, coating products, fillers, putties, plasters, modelling clay, washing & cleaning products, adhesives and sealants, cosmetics and personal care products, lubricants and greases and polishes and waxes.

This substance is used in the following areas: building & construction work, printing and recorded media reproduction, formulation of mixtures and/or re-packaging and agriculture, forestry and fishing. This substance is used for the manufacture of: textile, leather or fur and wood and wood products.

This substance is used in the following activities or processes at workplace: roller or brushing applications, mixing in open batch processes, non-industrial spraying, treatment of articles by dipping and pouring and manual maintenance (cleaning and repair) of machinery.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products, polymers and fillers, putties, plasters, modelling clay. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in the production of articles, manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: coating products, fillers, putties, plasters, modelling clay and polymers.

This substance is used in the following areas: mining and building & construction work. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures and manufacturing of the substance. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Agru Oberflächentechnik GmbH, Steyrstrasse 31 4595 Waldneukirchen Oberösterreich Austria
  • AKZO Nobel Car Refinishes B.V., Rijksstraatweg 31 2170 BA Sassenheim Netherlands
  • Alteo Gardanne, Route de Biver BP 20062 13541 GARDANNE cedex France
  • ALUCOM AG, Giulinistraße 2 D-67065 Ludwigshafen Germany
  • ALUMINA ESPAÑOLA, S.A., Pedro Teixeira, 8 28020 Madrid Spain
  • Aluminium Oxid Stade GmbH, Johann-Rathje-Köser-Strasse 21683 Stade-Bützfleth Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • AromataGroup, Via Carolina Romani n. 35 20091 Bresso (MI) Italy
  • Baikowski, 1046 route de chaumontet -BP501 74330 Poisy France
  • BASF Nederland B.V., Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands
  • BASF Schwarzheide GmbH, Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany
  • BCS Only Representative Services Ltd 023, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
  • BENS consulting d.o.o., Bakovniška 7 1241 Kamnik Slovenia
  • Borealis AG, Trabrennstrasse 6-8 1020 Vienna Austria
  • Caplinq Europe BV, Industrieweg 15E 1566JN Assendelft - Netherlands
  • Carl Spaeter GmbH, Philosophenweg 17 47053 Duisburg Germany
  • CCD (Germany) GmbH, Berliner Allee 55 40212 Düsseldorf Germany
  • CellMark Deutschland GmbH, Hamborner Straße 53 D - 40547 Düsseldorf Germany Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemreach GmbH, Akazienweg 30 48317 Drensteinfurt Germany
  • Chemservice GmbH - (T1N3), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice S.A. – (L8U4), 13, Fausermillen 6689 Mertert Luxembourg
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Colorants Solutions Deutschland GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Colorants Solutions Deutschland GmbH - BR01, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Colorants Solutions Deutschland GmbH - MX02, Brueningstrasse 50 65929 Frankfurt am Main Germany
  • CRCP GmbH, Am Römerhof 51 60486 Frankfurt am Main Germany
  • Croda Denmark A/S, Elsenbakken 23 3600 Frederikssund Denmark
  • CS Regulatory IRL Ltd 1L-13, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • CSI-OR28DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
  • CSI-OR44DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland
  • CSI-OR45DUB, Block C Ardilaun Court 112-114 St. Stephen’s Green D02 YP23 Dublin Ireland
  • Cytec Engineered Materials GmbH in its legal capacity as OR of Cytec Industries Inc., Industriestraße 3 76684 Östringen Germany
  • Daicel Safety Systems Europe Sp. z o.o., ul. Strefowa 6 58-130 Zarow Poland
  • DEKRA Assurance Services GmbH OR12, Handwerkstraße 15 70565 Stuttgart Germany
  • Dow Silicones Belgium SPRL OR-2, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-3, PSRC - Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium
  • EASTCHEM SPÓŁKA Z OGRANICZONĄ ODPOWIEDZIALNOŚCIĄ, Kromołowska 78 42-400 Zawiercie Poland
  • EcoloChem Magyaróvár Termelő Kft., Timföldgyári utca 13.B.ép 9200 Mosonmagyaróvár Hungary
  • EcoMundo, 215, rue Jean-Jacques Rousseau 92130 Issy-les-Moulineaux France
  • Eurallumina SpA, Portovesme 09010 Portoscuso Sardegna Italy
  • Glencore Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • H.C. Starck Tungsten GmbH, Nymphenburger Straße 84 80335 München Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Hydro Aluminium AS, Drammensveien 260 0240 OSLO Norway
  • Hydro Extrusion Sweden AB, Metallvägen 574 81 Vetlanda Sweden
  • ICL Europe Coöperatief U.A., Prinsenhof Building Koningin Wilhelminaplein 30 1062 KR Amsterdam NH Netherlands
  • Industrias Quimicas del Ebro, Poligono Malpica Calle D 97 50016 Zaragoza Spain
  • Intertek Deutschland GmbH 46, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Johnson Matthey Chemicals GmbH (OR), Wardstraße 17 46446 Emmerich am Rhein Germany
  • Johnson Matthey Chemicals GmbH (OR2), Wardstraße 17 D-46446 Emmerich-am-Rhein Germany
  • Knoell NL-OR-S29, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Kobo Products SAS, 135 Rue Buissonnière Quartier Bouysset 31670 Labège France
  • Kuraray Europe GmbH, Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • LCW - SENSIENT COSMETIC TECHNOLOGIES, 7-9, Rue de l'Industrie 95310 Saint Ouen L'Aumône Val d'Oise France
  • Lighttech Lámpatechnológiai Kft., Hegyrejáró u. 1. 2120 Dunakeszi Pest Hungary
  • Livbag, Route du Beuzit F-29590 Pont-de-Buis France
  • Lovochemie, a.s., Terezinska 57 410 02 Lovosice Czech Republic
  • MARTINSWERK GMBH, Koelnerstrasse, 110 50127 BERGHEIM Germany
  • Master Builders Solutions GmbH, Roseggerstrasse 101 attn. EHSQ Department 8670 Krieglach Austria
  • Master Builders Solutions Italia S.P.A., Via Vicinale delle Corti 21 attn. EHSQ Department 31100 Treviso (TV) Italy
  • Merck Surface Solutions GmbH, Mainzer Str. 41 64579 Gernsheim Germany
  • Mitsubishi Polyester Film GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • MYTILINEOS HOLDINGS plant ALUMINIUM OF GREECE , Agios Nikolaos 320 03 Aspra Spitia Viotia Greece
  • Nabaltec AG, Alustr. 50-52 92421 Schwandorf Germany
  • Nagase (Europa) GmbH, Werdener Straße 4 40227 Düsseldorf Germany
  • Norilsk Nickel Harjavalta Oy, Teollisuuskatu 1 FI-29200 Harjavalta Finland
  • NYX PROFESSIONAL MAKEUP SPRL/BVBA, Avenue Charles-Quint 584 1082 Berchem-Sainte-Agathe Belgium
  • Panasonic Industrial Devices Slovakia s.r.o., Oravicka 616 02801 Trstena Slovakia
  • Parker Hannifin Manufacturing Germany GmbH & Co. KG, Ottostrasse 28 41836 Hueckelhoven Northrhine Westfalia Germany
  • Piesslinger GmbH, Im Gstadt 1 4591 Molln Austria
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • Quarzwerke GmbH, Kaskadenweg 40 50226 Frechen Germany
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 Box 5 B-1040 Brussels Belgium
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H Consulting Group, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP (SHANDONG TAIXING ADVANCED MATERIAL CO., LTD.), Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • Ricardo Nederland BV, Catharijnesingel 33 3511 GC Utrecht Netherlands
  • Richard Baker Harrison (Ireland) Limited , Unit 8 Sandyford Business Centre Blackthorn Road Dublin 18 Sandyford Ireland
  • Roche Diagnostics GmbH, Sandhoferstrasse 116 68305 Mannheim Germany
  • Rusal Aughinish Alumina, Aughinish Island 0000 Askeaton County Limerick Ireland
  • Sasol Germany GmbH, Anckelmannsplatz 1 D-20537 Hamburg Germany
  • SC Alum SA, Isaccei 820228 Tulcea Tulcea Romania
  • SC Autoliv Romania SRL, Street Bucegi no.8 500053 Brasov Romania
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • Showa Denko Europe GmbH (SDK), Daimlerstrasse 19 86368 Gersthofen Germany
  • Sika Sverige AB, P O Box 8061 Domnarvsgatan 15 163 08 Spånga Sweden
  • SILKEM Hungary Korlátolt Felelősségű Társaság, Fehérvári út 26 H-8104 Várpalota Veszprém Hungary
  • SMC Minerals & Chemicals AB, Stortorget 29 211 34 Malmö Sweden
  • StonCor Europe, Rue du Travail, 9 1400 Nivelles Belgium
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • TDK FOIL ITALY SPA, Via E.C.H. Rosenthal 5 20089 Rozzano Italy
  • TÜV SÜD Industrie Service GmbH (12), Westendstraße 199 80686 Munich Germany
  • TÜV SÜD Industrie Service GmbH (15), Westendstrasse 199 80686 Munich Germany
  • United Company Rusal Aluminium Limited, Thermistokli Dervis Street, 5 Elenion Building, 2nd floor 1066 Nikosia Cyprus
  • United Company Rusal Aluminium Limited, Themistokli Dervis Street, 5 Elenion Building, 2nd floor 1066 Nikosia Cyprus
  • UOP S.r.l._OR001, Viale Milanofiori Strada 1 - Palazzo E1 I-20090 Assago Milan Italy
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • Wacker Chemie AG (OR_WCC), Johannes-Hess-Strasse 24 84489 Burghausen Germany
  • Wacker Chimie S.A.S., 11 bis, quai Perrache Bureaux Convergence Batiment C 69002 Lyon France
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • BASF A/S, Ved Stadsgraven 15 Postboks 4042 2300 Kopenhagen Denmark
  • BASF AS, Lilleakerveien 2 C 0283 Oslo Norway
  • BASF Hellas S.A., 2 Paradissou Str. & Kifissias Ave. 15125 Maroussi, Athens Greece
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Flint CPS Inks Germany GmbH - NA, Sieglestrasse 25 70464 Stuttgart Germany
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium
  • Only representative (No publishable name), null
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • The Bergquist Company GmbH, Verbindungsweg 42 25469 Halstenbek Germany

Substance names and other identifiers

Aluminium hydroxide
EC Inventory, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
aluminium hydroxide
REACH pre-registration, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
Aluminum hydroxide, dried
Other
Aluminum hydroxide (Al(OH)3)
Other
Alumina hydrate
Registration dossier
ALUMINA TRIHYDRATE
C&L Inventory
ALUMINIUM HYDROXIDE
C&L Inventory, Registration dossier
Aluminium Hydroxide
C&L Inventory, Registration dossier
Aluminium hydroxide, Alumina hydrate
Registration dossier
Aluminium hydroxide_JS
Registration dossier
Aluminium hydroxyde
C&L Inventory
aluminium trihydrate
C&L Inventory
Aluminium trihydrate
Registration dossier
Aluminium trihydroxide
C&L Inventory, Registration dossier
aluminium(3+) ion trihydroxide
Registration dossier
aluminium(3+) trihydroxide
C&L Inventory, Registration dossier, Other
aluminium(III) hydroxide
C&L Inventory
Aluminiumhydroxid
C&L Inventory
aluminuim hydroxide
Registration dossier
ALUMINUM HYDROXIDE
C&L Inventory, Registration dossier
Aluminum hydroxide
C&L Inventory, Registration dossier
Aluminum hydroxide (Al(OH)3)
C&L Inventory
Aluminum hydroxide (Al(OH)3)
Registration dossier
Aluminum Trihydrate
C&L Inventory
Aluminum trihydroxide
C&L Inventory, Registration dossier
ATH
Registration dossier
Hydrate
Registration dossier
Sulcabai
Registration dossier
AB H-Series Alumina Trihydrate
Registration dossier
Actilox
Registration dossier
ALH-……
Registration dossier
ALOLT-……….
Registration dossier
Alumina Hydrate
Registration dossier
Aluminium hydrate
Registration dossier
Aluminium Hydroxide
Registration dossier
Aluminium trihydroxide
Registration dossier
Aluminiumhydroxid
Registration dossier
Aluminum hydroxide
Registration dossier
Aluminum hydroxide highly dispersed precipitated
Registration dossier
aluminum trihydrate
Registration dossier
Apyral
Registration dossier
BARIACE
Registration dossier
BARIFINE
Registration dossier
Bayerit
Registration dossier
Geloxal
Registration dossier
Hydrate
Registration dossier
Hydrated alumina
Registration dossier
hydroxid hlinitý
Registration dossier
HYMOD® Surface-Treated Alumina Trihydrate
Registration dossier
JR-800, MT-500SA etc.
Registration dossier
KB-30, HS , HC, Hydrate, Aluminium hydroxide
Registration dossier
MARTIFILL®
Registration dossier
MARTIFIN®
Registration dossier
MARTINAL®
Registration dossier
MICRAL® Alumina Trihydrate
Registration dossier
MOLDX® Optimized Alumina Trihydrate
Registration dossier
ONYX ELITE® Alumina Trihydrate
Registration dossier
R-11P
Registration dossier
SB Alumina Trihydrate
Registration dossier
Sigunit
Registration dossier
SSP
Registration dossier
STR
Registration dossier
T-Lite
Registration dossier
VOGA
Registration dossier
Aluminium oxide, hydrate
REACH pre-registration
Aluminum hydroxide (Al(OH)3)
REACH pre-registration
Aluminum oxide (Al2O3), hydrate
REACH pre-registration
106152-09-4
CAS number
Other
106152-09-4
Deleted CAS number
Other
1071843-34-9
CAS number
Other
1071843-34-9
Deleted CAS number
Other
12040-59-4
CAS number
Other
12040-59-4
Deleted CAS number
Other
12252-70-9
CAS number
Other
12252-70-9
Deleted CAS number
Other
128083-27-2
CAS number
Other
128083-27-2
Deleted CAS number
Other
1302-29-0
CAS number
Other
1302-29-0
Deleted CAS number
Other
1333-84-2
CAS number
Other
13783-16-9
CAS number
Other
13783-16-9
Deleted CAS number
Other
151393-94-1
CAS number
Other
151393-94-1
Deleted CAS number
Other
156259-59-5
CAS number
Other
156259-59-5
Deleted CAS number
Other
159704-77-5
CAS number
Other
159704-77-5
Deleted CAS number
Other
16657-47-9
CAS number
Other
16657-47-9
Deleted CAS number
Other
1847408-13-2
CAS number
Other
1847408-13-2
Deleted CAS number
Other
21645-51-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
227961-51-5
CAS number
Other
227961-51-5
Deleted CAS number
Other
51330-22-4
CAS number
Other
51330-22-4
Deleted CAS number
Other
546141-62-2
CAS number
Other
546141-62-2
Deleted CAS number
Other
546141-68-8
CAS number
Other
546141-68-8
Deleted CAS number
Other
8012-63-3
CAS number
Other
8012-63-3
Deleted CAS number
Other
8064-00-4
CAS number
Other
8064-00-4
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 6 studies submitted
  • 1 study processed
R Melting / freezing point
300 °C [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
300 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
2 980 °C

Density

Study results
  • 9 studies submitted
  • 2 studies processed
R Density
2.42 g/cm³ [1]
R Relative density
2.42 [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 9
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
2.42

Vapour pressure

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 9 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
90 µg/L @ 20 °C and pH 6 - 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
90 µg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) Insufficient data available (further information necessary) (1)
Sediment (marine water) Insufficient data available (further information necessary) (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil Insufficient data available (further information necessary) (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 17 studies submitted
  • 14 studies processed
P/RResults
LC50 (16 days) 430 - 3 910 µg/L [4]
LC50 (8 days) 22.4 mg/L [1]
LC50 (4 days) 570 - 218 644.1 µg/L [20]
LC50 (4 days) 2.9 µmol/L [1]
LC50 (72 h) 10 - 19.3 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 14
Other 2 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 20 studies submitted
  • 18 studies processed
P/RResults
NOEC (60 days) 88 - 350 µg/L [4]
NOEC (33 days) 71.5 - 558.1 µg/L [7]
NOEC (30 days) 57 - 88 µg/L [3]
NOEC (28 days) 4.7 - 23.1 mg/L [4]
NOEC (7 days) 25.1 - 56 476.6 µg/L [29]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 18
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 13 studies submitted
  • 12 studies processed
P/RResults
EC50 (48 h) 1.5 - 2.56 mg/L [3]
LC50 (4 days) 22 - 30.6 mg/L [2]
LC50 (48 h) 5.7 - 99 600 µg/L [17]
NOEC (4 days) 22.6 mg/L [1]
NOEC (48 h) 5 - 671.2 µg/L [7]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 12
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 18 studies submitted
  • 16 studies processed
P/RResults
NOEC (42 days) 232.6 - 453.8 µg/L [4]
NOEC (30 days) 1.092 - 2.099 mg/L [2]
NOEC (28 days) 53.1 - 4 281.8 µg/L [5]
NOEC (21 days) 76 - 600 µg/L [3]
NOEC (17 days) 962.5 µg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 16
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 12 studies submitted
  • 12 studies processed
P/RResults
EC50 (4 days) 5.4 - 570 µg/L [5]
EC50 (72 h) 16.9 - 1 799 µg/L [25]
NOEC (72 h) 4 - 600 µg/L [11]
LOEC (72 h) 400 - 1 000 µg/L [6]
EC10 (72 h) 203 - 3 155 000 ng/L [29]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 12
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (7 days) 8.643 - 15.966 mg/L [3]
NOEC (7 days) 2.76 mg/L [3]
NOEC (4 days) 45.7 mg/L [1]
LOEC (7 days) 5.314 mg/L [3]
EC10 (7 days) 2.175 - 4.545 mg/L [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
200 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 10.76 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 10.76 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.74 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2 1
Supporting study 2
Weight of evidence 1
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 6 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 4 studies submitted
  • 3 studies processed
P/RResults
LC50 (4 h) 888 - 2 300 mg/m³ air (rat) [2]
LC50 (60 min) 7.6 mg/L air (rat) [1]
LC0 (4 h) 888 mg/m³ air (rat) [1]
M/CInterpretations of results
Not classified [3]

inhalation
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 4 studies processed
P/RResults
NOAEL (rat): 200 - 3 225 mg/kg bw/day [6]
NOAEL (rat): 141 - 302 mg/kg diet [3]
NOAEL (dog): 1 034 - 1 087 mg/kg bw/day [2]
LOAEL (rat): 1 000 - 1 075 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 1 4
Other
Data waiving
no waivers
Study data: inhalation
  • 6 studies submitted
  • 4 studies processed
P/RResults
NOAEC (rat): 3 - 70 mg/m³ air [2]
NOAEC (guinea pig): 30 mg/m³ air [1]
NOAEC (hamster): 70 mg/m³ air [1]
LOAEC (rat): 28 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence 4
Other 1
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 1 6
Other 2
Data waiving
no waivers
Study data: in vivo
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence 1 4
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 1
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 1
Supporting study 4 1
Weight of evidence
Other 1
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant