Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-959-5
CAS no.:
7782-50-5
Index number:
017-001-00-7
Molecular formula:
Cl2
SMILES:
ClCl
InChI:
InChI=1S/Cl2/c1-2
Type of substance:
Mono constituent substance
Origin:
Element, Inorganic
Registered compositions:
23
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01corr) approved by the European Union, this substance is toxic if inhaled, is very toxic to aquatic life, may cause or intensify fire (oxidiser), causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is fatal if inhaled, is very toxic to aquatic life with long lasting effects and contains gas under pressure and may explode if heated.

Breakdown of all 1073 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Ox. Gas 1 H270 Harmonised Classification
Acute Tox. 2 H330
Press. Gas (Comp.) H280
Acute Tox. 3 H331 Harmonised Classification
Press. Gas (Liq.) H280
Aquatic Chronic 1 H410
Acute Tox. 4 H302
STOT RE 2 H373
Press. Gas Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 89 active registrations under REACH, 2 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: disinfection, drinking water.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: preservation for liquid systems.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: biocides (e.g. disinfectants, pest control products) and washing & cleaning products.

This substance is used for the manufacture of: rubber products.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, transfer of chemicals at non-dedicated facilities, transfer of substance into small containers, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, hand mixing with intimate contact only with personal protective equipment available and the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following products: laboratory chemicals and semiconductors. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals at dedicated facilities, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and manufacturing of the substance.

This substance is used in the following products: semiconductors, metal surface treatment products, laboratory chemicals, water treatment chemicals and paper chemicals and dyes. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals, electrical, electronic and optical equipment, pulp, paper and paper products and metals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, transfer of chemicals and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, in processing aids at industrial sites and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep valves and fittings free from oil and grease; avoid release to the environment; do not breathe the dust, fume, gas, mist, vapours or spray; keep away from clothing or other combustible materials; keep container tightly closed; avoid breathing the dust, fume, gas, mist, vapours or spray; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Take off contaminated clothing and wash before reuse. In case of fire: stop leak if safe to do so. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Collect spillage. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance locked up; in a well-ventilated place and keeping container tightly closed; protected from sunlight and in a well-ventilated place.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AIR LIQUIDE FRANCE INDUSTRIE, EL- AMC-EMC Chalon Archibald Scandocs Center / 0715 - CS 80010 81700 BLAN France
  • ALBEMARLE EUROPE SPRL, Parc Scientifique (Einstein) Rue du Bosquet 9 1348 LOUVAIN-LA-NEUVE Belgium
  • ANWIL SA, Torunska 222 87-805 Wloclawek kuj-pom Poland
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • ARLANXEO Netherlands B.V. (OR for Canada), Urmonderbaan 24 6167 RD Geleen Netherlands
  • B.I.G. - OR634, Technische Schoolstraat 43A 2440 Geel Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BD&I_37, rue Omer Lepreux, 92 1081 bruxelles Belgium Belgium
  • Bison International B.V., Dr. A.F. Philipsstraat 9 4462 EW Goes Netherlands
  • BOC Gases Ireland Ltd, John F Kennedy Drive Bluebell D12 PP63 Dublin Ireland
  • Bondalti Cantábria S.A, Avenida Rey Alberto I de Bélgica s/n, 39300 Torrelavega Cantábria Spain
  • BONDALTI CHEMICALS, S.A., Quinta da Industria Beduido 3860-680 Estarreja Portugal
  • BorsodChem, Bolyai ter 1 3700 Kazincbarcika Hungary
  • CABB GmbH, Ludwig-Hermann-Str. 100 86368 Gersthofen Germany
  • CAFFARO BRESCIA S.r.l, viale Sondrio 2 20124 Milano Italy
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin 02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemra GmbH, Max-Planck-Strasse 12 54296 Trier Germany
  • Chimcomplex S.A. Borzesti, 3, Industriilor Street 601124 Onesti Bacau Romania
  • CHS Epi, a.s., Revoluční 1930/6 40032 Ústí nad Labem Czech Republic
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • COVESTRO, S.L., C/. Feixa LLarga, 7 08040 Barcelona Spain
  • DKSH GmbH, Baumwall 3 20459 Hamburg Germany
  • DniproAZOT Trade, Stochovska 50/821 16100 Praha Czech Republic
  • Donau Chemie Aktiengesellschaft, Am Heumarkt 10 1037 Vienna Vienna Austria
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH, Buetzflether Sand 2 D-21683 Stade Germany
  • DSP S.A.S., 22, rue Brunel 75017 Paris France
  • Eastman Chemical B.V., Watermanweg 70 3067 GG Rotterdam Netherlands
  • ELECTROQUÍMICA DE HERNANI, S.A., EPELE 20120 HERNANI Spain
  • Electroquímica Onubense, S.L., Industrial Nuevo Puerto, 0 21810 Palos de la Frontera Huelva Spain
  • Ercros SA, Avenida Diagonal 593-595 08014 Barcelona Spain
  • Evonik Functional Solutions GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • FORTISCHEM a.s., M.R.Stefanika 1 972 71 Novaky Slovakia
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17, 22363 Lund Sweden
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • HALO INDUSTRY S.P.A, piazzale Franco Marinotti 1 33050 TORVISCOSA (UD) Italy
  • HydroChem Italia S.r.l., Via Mario Massari, 30/32 IT-28886 Pieve Vergonte VB Italy
  • INEOS Chlor Atlantik GmbH, Inhausersieler Str. 25 26388 Wilhelmshaven Niedersachsen Germany
  • INOVYN Belgium SA, Rue Solvay 39 5190 Jemeppe Sur Sambre Belgium
  • INOVYN Deutschland GmbH, Luwigstrasse 12 47495 Rheinberg Germany
  • INOVYN France S.A.S., Avenue de la République 39500 Tavaux France
  • INOVYN Manufacturing Belgium SA, Rue Solvay 39 5190 Jemeppe Sur Sambre Belgium
  • INOVYN Norge AS, Rafnes N-3966 STATHELLE Norway
  • INOVYN Produzione Italia S.p.A, VIA PIAVE, 6 57013 ROSIGNANO SOLVAY LIVORNO Italy
  • INOVYN Sverige AB, Hjälmarevägen 444 83 Stenungsund Sweden
  • Intertek Deutschland GmbH 49, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Kaustik Europe b.v., Wijnhaven 3L 3011WG Rotterdam Netherlands
  • Kem One, IMMEUBLE LE QUADRILLE 19 RUE JACQUELINE AURIOL 69008 LYON France
  • KRONOS EUROPE S.A./N.V., Langerbruggekaai 10 9000 Gent Belgium
  • KRONOS TITAN GmbH, Peschstrasse 5 51373 Leverkusen Germany
  • Linde GmbH Gases Division, Seitnerstrasse 70 82049 Pullach Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Martin Grima Ltd, Ghajn Astas, St. Paul's Bay SPB 6930 Ghajn Astas Malta
  • Momentive Performance Materials GmbH, Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany
  • MSSA, Pombliere 73600 Saint Marcel France
  • Neolyse Ibbenbüren GmbH, Hauptstraße 47 49479 Ibbenbüren Germany
  • Nobian GmbH, Hauptstraße 47 49479 Ibbenbüren Germany
  • Nobian Industrial Chemicals B.V., Van Asch van Wijckstraat 53 3811 LP Amersfoort Netherlands
  • NOROO BEE Chemical Czech s. r. o., Kopaná 1792 744 01 Frenštát pod Radhoštěm Czech Republic
  • Only representative (No publishable name), null
  • OQEMA GmbH, Aachener Str. 258 41061 Moenchengladbach Germany
  • PCC Rokita SA, Sienkiewicza 4 56-120 Brzeg Dolny Poland
  • PetroChina International (Netherlands) Company B.V, Toren A, 11th Floor 3012NJ Rotterdam Netherlands
  • QUÍMICA DEL CINCA, S.L., Avda. Diagonal 352 08013 Barcelona Barcelona Spain
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo, Finland. 02710 Espoo Finland
  • Resonac Europe GmbH (SDK), Daimlerstrasse 19 86368 Gersthofen Germany
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SPOLANA s.r.o., Ul. Práce 657 277 11 Neratovice Czech Republic
  • TKI Hrastnik d.d., Za Savo 6 1430 Hrastnik Slovenia
  • TOSOH EUROPE B.V., Amstelplein 1 1096 HA Amsterdam Netherlands
  • TramacoGmbH, Lise-Meitner-Allee 8 25411 Tornesch Germany
  • Vencorex France_1, 196 Allée Alexandre Borodine 69800 Saint Priest France
  • VESTOLIT GmbH, Paul-Baumann-Str. 1 45772 Marl Germany
  • Vynova PPC SAS, 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • Westlake Vinnolit GmbH & Co. KG, Carl-Zeiss-Ring 25 85737 Ismaning Germany
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • Borregaard AS, Hjalmar Wessels vei 6 1701 Sarpsborg Norway
  • ELNOSA – ELECTROQUÍMICA DEL NOROESTE, SA, MARISMA DE LOURIZÁ S/N APT. 265 36153 PONTEVEDRA Spain
  • Eni Rewind S.p.A., Piazza Boldrini 1 20097 San Donato Milanese Milano Italy
  • Hellenic Petroleum R.S.S.O.P.P. S.A., 8A Chimarras street 15125 Marousi Attica Greece
  • Kemira Chemicals Oy, Harmajantie 3 P.O Box 7 FI-32741 SASTAMALA Finland
  • REACH COMPLIANCE SERVICES LIMITED, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • Specialty Electronic Materials Netherlands BV OR-5, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • YANG BUSINESS CONSULTANCY LIMITED, 53 RODNEY STREET, LIVERPOOL, MERSEYSIDE L1 9ER LIVERPOOL MERSEYSIDE, ENGLAND United Kingdom
  • ZACHEM S.A., Wojska Polskiego 65 85-825 Bydgoszcz Poland

Substance names and other identifiers

Active chlorine released from chlorine
Biocidal active substances
Bertholite
Other
Bertholite /warfare gas/
Other
Chloor
Other
Chlor
Other
Chlore
Other
Chlorine
EC Inventory, C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, IPPC - Industrial Emissions Directive, Annex II - Polluting Substances, IPPC, Annexes V, VI, VIII - Provisions relating to industrial plants, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Occupational Exposure Limits - 2nd list - Indicative OELVs, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
CHLORINE
C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, IPPC - Industrial Emissions Directive, Annex II - Polluting Substances, IPPC, Annexes V, VI, VIII - Provisions relating to industrial plants, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Occupational Exposure Limits - 2nd list - Indicative OELVs, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Chlorine gas
Other
Chlorine mol.
Other
CHLORINE, ADSORBED
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
Chlorine-elemental
Other
Chlorinum
Other
Cloro
Other
Aktivchlor, freigesetzt aus Chlor (de)
Biocidal active substances
aktivni klor oslobođen iz klora (hr)
Biocidal active substances
Aktivni klor, sproščen iz klora (sl)
Biocidal active substances
aktivní chlor uvolněný z chloru (cs)
Biocidal active substances
Aktivt chlor frigivet fra chlor (da)
Biocidal active substances
Aktivt klor frigjort fra klor (no)
Biocidal active substances
Aktivt klor frisatt från klor (sv)
Biocidal active substances
Aktywny chlor uwalniany z chloru (pl)
Biocidal active substances
Aktívny chlór uvoľnený z chlóru (sk)
Biocidal active substances
chloor (nl)
C&L Inventory
chlor (da)
C&L Inventory
Chlor (de)
C&L Inventory
Chlor (pl)
C&L Inventory
chloras (lt)
C&L Inventory
chlore (fr)
C&L Inventory
Chlore actif libéré à partir de chlore (fr)
Biocidal active substances
chlór (cs)
C&L Inventory
chlór (sk)
C&L Inventory
clor (mt)
C&L Inventory
clor (ro)
C&L Inventory
Clor activ eliberat din clor (ro)
Biocidal active substances
cloro (es)
C&L Inventory
cloro (it)
C&L Inventory
cloro (pt)
C&L Inventory
Cloro activo liberado a partir de cloro (es)
Biocidal active substances
Cloro ativo libertado por cloro (pt)
Biocidal active substances
Cloro attivo rilasciato da cloro (it)
Biocidal active substances
hlors (lv)
C&L Inventory
Iš chloro išskirtas aktyvusis chloras (lt)
Biocidal active substances
kloor (et)
C&L Inventory
Kloori (fi)
C&L Inventory
Kloorist vabanenud aktiivkloor (et)
Biocidal active substances
Kloorista vapautunut aktiivinen kloori (fi)
Biocidal active substances
klor (hr)
C&L Inventory
klor (no)
C&L Inventory
klor (sl)
C&L Inventory
klor (sv)
C&L Inventory
Kloru attiv rilaxxat mill-kloru (mt)
Biocidal active substances
klór (hu)
C&L Inventory
Klórból felszabaduló aktív klór (hu)
Biocidal active substances
No hlora izdalījies aktīvais hlors (lv)
Biocidal active substances
Uit chloor vrijgekomen actief chloor (nl)
Biocidal active substances
Ενεργό χλώριο εκλυόμενο από χλώριο (el)
Biocidal active substances
χλώριο (el)
C&L Inventory
Активен хлор, отделен от хлор (bg)
Biocidal active substances
хлор (bg)
C&L Inventory
Active chlorine released from chlorine
Biocidal active substances
Bondalti Chlorine
Registration dossier
Chlor
Registration dossier
Chlorine
C&L Inventory, Registration dossier
CHLORINE
C&L Inventory, Registration dossier
dichlorane
Registration dossier
dichlorine
Registration dossier, Other
molecular chlorine
C&L Inventory, Registration dossier, Other
caswellno179
Registration dossier
Chlor
C&L Inventory, Registration dossier
chlor gazowy
Registration dossier
chlor kapalný
Registration dossier
chlor plynný
Registration dossier
chlor skroplony
Registration dossier
Chlorinated polyethylene
Registration dossier
Chlorine
Registration dossier
Chlorine (6CI, 7CI, 8CI, 9CI)
Registration dossier
Chlorine mol.
Registration dossier
Chlorine molecule (Cl2)
Registration dossier
Cl2
Registration dossier
Diatomic chlorine
Registration dossier
Dichlorine
Registration dossier
High Purity Chlorine
C&L Inventory
Liquid Chlorine
Registration dossier
Liquid chlorine technical
Registration dossier
Molecular chlorine
Registration dossier
017-001-00-7
Index number
C&L Inventory
7782-50-5
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, IPPC - Industrial Emissions Directive, Annex II - Polluting Substances, IPPC, Annexes V, VI, VIII - Provisions relating to industrial plants, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Occupational Exposure Limits - 2nd list - Indicative OELVs, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Gaseous (100%) [2]
C Form
Liquified gas (100%) [2]
C Odour
Other (100%) [2]
C Substance type
Element (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Gaseous (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
-101.03 °C

Boiling point

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Boiling point at 101 325 Pa
-34.03 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
3.21 @ 0 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
678 - 778.7 kPa @ 20 - 25 °C [4]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
678 kPa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
-0.85 @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Log Kow (Log Pow)
-0.85 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
5.91 - 9.78 g/L @ 10 - 30 °C and pH 7 [6]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
7.41 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Surface tension at 20 °C
82.4 mN/m @ 316 mg/L

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
Yes (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 2 studies processed
C Dissociating properties
Yes (100%) [2]
R Dissociation constant
7 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
0.013 - 13.3 [6]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Dynamic viscosity at 20 °C
0.013 - 13.3 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 4 studies submitted
  • 2 studies processed
R Dissipation half life (DT50)
78 - 11 436 min [20]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 2 studies processed
R Dissipation Half-life (DT50)
12 - 60 min [6]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 210 ng/L (2)
Intermittent releases (freshwater) 260 ng/L (2)
Marine water 42 ng/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 30 µg/L (2)
Sediment (freshwater) No exposure of sediment expected (2)
Sediment (marine water) No exposure of sediment expected (2)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No exposure of soil expected (2)
Hazard for Predators
Secondary poisoning 11.1 mg/kg food (2)

Short–term toxicity to fish

Study results
  • 76 studies submitted
  • 3 studies processed
P/RResults
LC50 (5 days) 50 µg/L [6]

Type of Study provided
Studies with data
Key study 7
Supporting study 66
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 84 studies submitted
  • 11 studies processed
P/RResults
EC50 (48 h) 26 - 141 µg/L [7]
LC50 (72 h) 90 - 180 µg/L [4]
LC50 (48 h) 29 - 260 µg/L [14]
LC50 (24 h) 70 - 55 000 µg/L [14]
NOEC (48 h) 25 - 50 µg/L [4]

Type of Study provided
Studies with data
Key study 1 4
Supporting study 72
Weight of evidence 6
Other 1
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 15 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 1 study processed
P/RResults
NOEC (24 h) 400 µg/L [1]

Type of Study provided
Studies with data
Key study 4
Supporting study 26
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater algae
23 µg/L
EC50 for marine water algae
400 µg/L
EC10 or NOEC for freshwater algae
2.1 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 100 - 400 µg/L [2]
NOEC (4 days) 20 - 50 µg/L [10]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for freshwater plants
100 µg/L
EC10 or NOEC for freshwater plants
20 µg/L

Toxicity to microorganisms

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
EC50 (3 h) 3 - 563 mg/L [5]
NOEC (3 h) 41.1 - 300 mg/L [2]
EC10 (3 h) 46.9 - 342 mg/L [2]

Type of Study provided
Studies with data
Key study 1 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for microorganisms
3 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 2
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 2
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 9 studies submitted
  • 3 studies processed
P/RResults
NOEC (70 days) 200 mg/L drinking water [2]
LOEC (70 days) 400 mg/L drinking water [2]
NOEL (70 days) 200 mg/L drinking water [1]
LOEL (70 days) 400 mg/L drinking water [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Long-term EC10 / LC10 / NOEC
200 mg/kg food

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 750 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.5 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 750 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.5 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: - -
Acute /short term: No hazard identified
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 750 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.5 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 750 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.5 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: - -
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 250 µg/kg bw/day repeated dose toxicity
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4
Supporting study 10
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 10 studies submitted
  • 2 studies processed
P/RResults
LD50 1 100 mg/kg bw (rat) [2]
LD0 626 mg/kg bw (rat) [2]
M/CInterpretations of results
Study cannot be used for classification [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 28 studies submitted
  • 4 studies processed
P/RResults
LC50 (60 min) 834 - 1 321 mg/m³ air (rat) [2]
LC50 (30 min) 1.248 - 2.033 mg/L air (rat) [2]
LC50 (10 min) 2.986 - 5.642 mg/L air (rat) [2]
LC50 (5 min) 7.26 - 15.949 mg/L air (rat) [2]
LC50 (30 min) 1.462 mg/L air (mouse) [2]
M/CInterpretations of results
Category 3 based on GHS criteria [2]

inhalation
Studies with data
Key study 4
Supporting study 24
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 2 studies processed
P/RResults
LD50 20 000 mg/kg bw (rabbit) [2]
LD0 14 420 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 27 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 24
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 6
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 29 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 16.7 - 57.2 mg/kg bw/day [8]
NOAEL (mouse): 34.4 mg/kg bw/day [2]
LOAEL (rat): 16.7 - 114.4 mg/kg bw/day [8]
LOAEL (mouse): 34.4 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 2 4
Supporting study 22
Weight of evidence
Other 1
Data waiving
no waivers
Study data: inhalation
  • 10 studies submitted
  • 2 studies processed
P/RResults
NOAEL (monkey): 0.5 ppm [2]
LOAEL (monkey): 2.3 ppm [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 42 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 10
Supporting study 30
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: in vivo
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1 14
Supporting study 9
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4 10
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant