Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-838-7
CAS no.:
7758-29-4
Index number:
Molecular formula:
H5O10P3.5Na
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[O-][P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])([O-])=O
InChI:
InChI=1S/5Na.H5O10P3/c;;;;;1-11(2,3)9-13(7,8)10-12(4,5)6/h;;;;;(H,7,8)(H2,1,2,3)(H2,4,5,6)/q5*+1;/p-5
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
18
Of which contain:
1 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Breakdown of all 3491 C&L notifications submitted to ECHA

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 25 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, perfumes and fragrances, pharmaceuticals, cosmetics and personal care products, pH regulators and water treatment products, paper chemicals and dyes and textile treatment products and dyes.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: water softeners, washing & cleaning products, pH regulators and water treatment products, water treatment chemicals, adhesives and sealants, coating products, metal surface treatment products, inks and toners, metal working fluids, photo-chemicals, polishes and waxes and polymers.

This substance is used in the following areas: health services, municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and building & construction work. This substance is used for the manufacture of: metals and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, hand mixing with intimate contact only with personal protective equipment available, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, roller or brushing applications and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: washing & cleaning products.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of chemicals, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: pH regulators and water treatment products, water softeners, washing & cleaning products, water treatment chemicals, metal surface treatment products, leather treatment products, metal working fluids and textile treatment products and dyes.

This substance is used in the following areas: mining and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, textile, leather or fur, plastic products, metals, fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, hand mixing with intimate contact only with personal protective equipment available, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: as processing aid and in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of chemicals at dedicated facilities, transfer of substance into small containers and handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders).

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • "Alventa" Spółka Akcyjna, Karola Olszewskiego 25 32-566 Alwernia Małopolskie Poland
  • B-Lands Consulting (811232-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811546-3), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811692-3), OR of WUHAN WAKING LION CHEMICALS CO.,LTD 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • BK Giulini GmbH, Dr. A. Reimann-Strasse 2 D-68526 Ladenburg Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland Dublin Ardee Ireland
  • Chemische Fabrik Budenheim KG, Rheinstrasse 27 55257 Budenheim RLP Germany
  • COVANCE CLINICAL DEVELOPMENT SA 051, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • De Sangosse (Ireland) Limited, 1 CASTLEWOOD AVENUE RATHMINES D06 H685 DUBLIN Ireland
  • Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
  • Fosfa a.s., Hraniční 268 69141 Břeclav Czech Republic
  • Haifa North West Europe BVBA-SO, Generaal de Wittelaan 17, bus 16 B-2800 Mechelen Belgium
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • LTS REACH OR SCA, 15 Boulevard de Bury 16000 Angoulême France
  • PCC Rokita SA - OR1, Sienkiewicza 4 56-120 Brzeg Dolny Poland
  • PHOSINT LIMITED, 21 Vasili Michailidi 3026 Limassol Cyprus
  • PRAYON S.A., 144, rue Joseph Wauters 4480 ENGIS Belgium
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SUEZ Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • SUEZ WTS France, Tour CB21 16 Place de l’Iris 92040 Paris La Défense France
  • Thermphos International B.V., Europaweg Zuid 4, Haven 9890, 4389 PD Ritthem / Vlissingen Netherlands
  • TKI Hrastnik d.d., Za Savo 6 1430 Hrastnik Slovenia
  • TURCO ESPAÑOLA, S.A., C/ Feixa Llarga, 19 08040 Barcelona Barcelona Spain
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • FMC Foret S.A., Avenida Diagonal 530-532, 3ª planta 08006 Barcelona Spain
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom

Substance names and other identifiers

Pentasodium triphosphate
EC Inventory
pentasodium triphosphate
REACH pre-registration
Pentasodium tripolyphosphate
Other
Triphosphoric acid, sodium salt (1:5)
Other
diphosphono hydrogen phosphate
C&L Inventory
pentasodium [oxido(phosphonatooxy)phosphoryl] phosphate
C&L Inventory
pentasodium bis(phosphonatooxy)phosphinate
Registration dossier
pentasodium bis(phosphonooxy)phosphinate
Other
Pentasodium triphosphate
C&L Inventory, Registration dossier
Pentasodium triphosphate
C&L Inventory, Registration dossier
Pentasodium tripolyphosphate, Sodium tripolyphosphate pentabasic, Sodium triphosphate pentabasic
Registration dossier
pentasodium;[oxido(phosphonatooxy)phosphoryl] phosphate
Other
Sodium Tri Polyphosphate
Registration dossier
Sodium Tri Polyphosphate, STPP
Registration dossier
Sodium tripoliphosphate
Registration dossier
SODIUM TRIPOLYPHOSPHATE
C&L Inventory, Registration dossier
Sodium tripolyphosphate
C&L Inventory, Registration dossier
sodium tripolyphosphate ( STPP )
Registration dossier
Triphosphoric acid, pentasodium salt
C&L Inventory
Hi-M-211
Registration dossier
Hi-M-212
Registration dossier
Hi-M-216
Registration dossier
Hi-M-217
Registration dossier
Natriumtripolyphosphat
Registration dossier
Natriumtripolyphosphate S 500
Registration dossier
NTPP
Registration dossier
PentaSodium TriPhosphate
Registration dossier
Polypray - different commercial grades
Registration dossier
sodium triphosphate
Registration dossier
Sodium TriPolyPhosphate
Registration dossier
sodium tripolyphosphate anhydrous
Registration dossier
Sodium TriPolyPhosphate Phase I Premoistured
Registration dossier
Sodium tripolyphosphate, food grade
Registration dossier
Sodium tripolyphosphate, technical grade
Registration dossier
STPP
Registration dossier
STPP-GH
Registration dossier
STPP-GL
Registration dossier
STPP-GM
Registration dossier
STPP-HUPH
Registration dossier
STPP-HUPL
Registration dossier
STPP-HUPM
Registration dossier
STPP-PH
Registration dossier
STPP-PHB
Registration dossier
STPP-PL
Registration dossier
STPP-PM
Registration dossier
triphosphoric acid, pentasodium salt
Registration dossier
tripolyfosfát sodný
Registration dossier
1350716-07-2
CAS number
Other
1350716-07-2
Deleted CAS number
Other
1610338-39-0
CAS number
Other
1610338-39-0
Deleted CAS number
Other
187620-23-1
CAS number
Other
187620-23-1
Deleted CAS number
Other
2093160-08-6
CAS number
Other
2093160-08-6
Deleted CAS number
Other
7758-29-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
860389-18-0
CAS number
Other
860389-18-0
Deleted CAS number
Other
9010-08-6
CAS number
Other
9010-08-6
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 8 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Not specified (100%) [2]
C Substance type
Inorganic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
622 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 4 studies submitted
  • 2 studies processed
R Relative density
2.55 @ 21 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 16 studies submitted
  • 2 studies processed
R Water solubility (mass/vol.)
148 g/L @ 20 °C and pH 4 - 9 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
148 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 4 studies submitted
  • 2 studies processed
C Dissociating properties
Not determined (100%) [2]
R Dissociation constant
9.52 - 9.62 @ 25 - 40 °C [8]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 62 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 44 16
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Koc at 20°C
142.44

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 5 µg/L (2)
Intermittent releases (freshwater) 50 µg/L (2)
Marine water 5 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) -
Sediment (freshwater) 190 µg/kg sediment dw (2)
Sediment (marine water) -
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 140 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 8 studies submitted
  • 2 studies processed
P/RResults
LC50 (24 h) 1.85 g/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 14 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 4 studies processed
P/RResults
EC50 (7 days) 900 mg/L [2]
EC50 (4 days) 69.2 - 160 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 661 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 661 µg/m³ repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 375 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 375 µg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 661 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 660 µg/m³ repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 375 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 375 µg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 750 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 750 µg/kg bw/day repeated dose toxicity
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 2 10
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 28 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 10 2
Weight of evidence
Other 14
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 390 mg/m³ air (rat) [2]

inhalation
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 4 640 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 2 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 10 2
Weight of evidence
Other 6
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 8 studies submitted
  • 2 studies processed
P/RResults
NOAEL (dog): 100 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 4
Other
Study data: dermal
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 4
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study 8
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: in vivo
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant