Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-633-2
CAS no.:
7664-38-2
Index number:
015-011-00-6
Molecular formula:
H3O4P
SMILES:
OP(O)(O)=O
InChI:
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
50
Of which contain:
1 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is harmful if swallowed, causes serious eye damage and may be corrosive to metals.

Breakdown of all 4255 C&L notifications submitted to ECHA

Skin Corr. 1B H314 Harmonised Classification
Met. Corr. 1 H290
Eye Dam. 1 H318
Acute Tox. 4 H302
Acute Tox. 1 H300
Skin Corr. 1 H314
Eye Irrit. 2 H319
Not Classified
Skin Corr. 1C H314
STOT SE 3 H335
Skin Corr. 1A H314
Aquatic Chronic 3 H412
Skin Irrit. 2 H315
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 117 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: washing & cleaning products, fertilisers, welding & soldering products, polishes and waxes, plant protection products and pH regulators and water treatment products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, open transfer and processing with minerals/metals at elevated temperature, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting). Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: pH regulators and water treatment products, water treatment chemicals, metal surface treatment products and coating products.

This substance is used in the following areas: agriculture, forestry and fishing. This substance is used for the manufacture of: fabricated metal products, electrical, electronic and optical equipment and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, hand mixing with intimate contact only with personal protective equipment available, non-industrial spraying and transfer of substance into small containers.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, batch processing in synthesis or formulation with opportunity for exposure and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, as processing aid, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and in the production of articles.

This substance is used in the following products: pH regulators and water treatment products and coating products.

This substance is used in the following areas: building & construction work and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, food products and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep only in original packaging; do not breathe the dust, fume, gas, mist, vapours or spray; do not eat, drink or smoke when using this product; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Wash contaminated clothing before reuse. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a poison center or doctor/physician. Absorb spillage to prevent material damage. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Rinse the mouth. Follow specific treatment (see label). If swallowed: call a poison center or doctor/physician if you feel unwell.

Storage statements

Store this substance in a corrosive resistant container with a resistant inner liner (or in other specified container type); locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • "Alventa" Spółka Akcyjna, Karola Olszewskiego 25 32-566 Alwernia Małopolskie Poland
  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • ADP FERTILIZANTES, S.A., Estrada Nacional nº 10 - Apt 88 Salgados da Póvoa 2616-907 ALVERCA PORTUGAL Portugal
  • Agropolychim JSC, Industrial zone 9160 Devnya Varna Bulgaria
  • Allnex Belgium NV/SA OR2, Anderlechtstraat 33 1620 Drogenbos Belgium
  • ANNO chemicals N.V., Berkenlaan 21 2980 Halle (Zoersel) (Antwerp) Belgium
  • Anorel NV, Lintsesteenweg 632 2540 Hove Antwerpen Belgium
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • ARKEMA FEBEX, 420 rue Estienne d'Orves 92700 COLOMBES France
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • B-Lands Consulting (811232-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811546-3), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811553-5), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Beckman Coulter France SAS, Paris Nord 2 33 Rue des Vanesses 95942 Roissy CDG CEDE France
  • BENS consultnig d.o.o., Bakovniška 7 1241 Kamnik Slovenia
  • BK Giulini GmbH, Dr. A. Reimann-Strasse 2 D-68526 Ladenburg Germany
  • BRENNTAG S.p.A., Milanofiori Strada 6, Pal. A / 13 20057 ASSAGO (MI) Italy
  • Buckman Laboratories NV, Wondelgemkaai 157 9000 GENT Belgium
  • Budenheim Iberica S.L.U., C/ Extramuros S/N 50784 La Zaida ZARAGOZA Spain
  • BÜFA Chemikalien GmbH & Co. KG, An der Autobahn 14 27798 Hude / Altmoorhausen Germany
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • C.S.B. GmbH 0265, Düsseldorfer Straße 113 47809 Krefeld Germany
  • CF Groep B.V., Handelsweg 10 4231EZ Meerkerk Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemische Fabrik Budenheim KG, Rheinstrasse 27 55257 Budenheim RLP Germany
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemservice GmbH - (C3P2), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (J1F0), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (J2F0), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (J3F0), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (J4F0), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (J5F0), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (M3P9), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice S.A. - (Y4P9), 13, Fausermillen 6689 Mertert Luxembourg
  • Chemviron S.A., Zoning Industriel C de Feluy B - 7181 Feluy Belgium
  • Chevron Oronite SA M/I, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
  • CIBA VISION GmbH (OR CVCA), Industriering 1 63868 Großwallstadt Bavaria Germany
  • Clariant Plastics & Coatings (Deutschland) GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Clariant SE - SCSC, Am Unisyspark 1 65843 Sulzbach am Taunus Germany
  • Colorants Solutions Deutschland GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • COMPO Expert GmbH, Krögerweg 10 48155 Münster NRW Germany
  • Corteva Agriscience Italia S.r.l., via dei Comizi Agrari 10 26100 Cremona (CR) Italy
  • COVANCE CLINICAL DEVELOPMENT SA 049, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • CS3 GmbH, Grauertstrasse 12 81545 München Germany
  • Cytec Industries BV OR for UK, Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands
  • DEKRA Assurance Services GmbH OR02, Handwerkstr. 15 70565 Stuttgart Germany
  • DEKRA Assurance Services GmbH OR07, Handwerkstr. 15 70565 Stuttgart Germany
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-3, Postbus 48 4530 AA Terneuzen Netherlands
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont Solutions (France) SAS, Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancour France
  • Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
  • EuroChem Antwerpen NV, Haven 725, Scheldelaan 600 2040 Antwerp Belgium
  • Ferti-Solutions B.V., Zandtangerweg 46 9584AL Mussel Netherlands
  • Fertiberia, S.A., Paseo de la Castellana 259 D -Planta 48 28046 Madrid Spain
  • FERTINAGRO BIOTECH, S.L., Polig. Ind. La Paz,185 44195 Teruel Spain
  • Filo Chemical bv, Mercuriusweg 15 A 4382 NC Vlissingen Netherlands
  • Fosbel GmbH, Karstrasse 116 41068 Mönchengladbach Germany
  • Fosfa a.s., Hraniční 268 69141 Břeclav Czech Republic
  • FUJIFILM Electronic Materials (Europe) N.V., Keetberglaan 1A Haven 1061 2070 Zwijndrecht Antwerp Belgium
  • FUJIFILM Europe BV, Oudenstaart 1 5047 TK Tilburg Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • Grupa Azoty Zaklady Chemiczne "POLICE" Spolka Akcyjna, Kuznicka 1 72-010 Police Poland
  • Haifa North West Europe BVBA-SO, Generaal de Wittelaan 17, bus 16 B-2800 Mechelen Belgium
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Honeywell Belgium NV, Gaston Geenslaan 14 3001 Heverlee Belgium Belgium
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Str. 40 30926 Seelze Deutschland Germany
  • ICL Europe Coöperatief U.A., Prinsenhof Building Koningin Wilhelminaplein 30 1062 KR Amsterdam NH Netherlands
  • ICL Europe Coöperatief U.A. (OR1), Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands
  • Intertek Deutschland GmbH 56, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH CWCL, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, Ecoparc 2 27400 HEUDEBOUVILLE France
  • Jiangsu Chengxing Phosph-Chemicals Co., Ltd. (KONSENS OR), Kapellstr. 14 40479 Duesseldorf Germany
  • LANXESS Epierre SAS, Rue de l'Andraye Usine d'Epierre 73220 Epierre France
  • Lifosa, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • Lifosa-3, Juodkiskio 50 LT-57502 Kedainiai Lithuania
  • LinmarkOR91, Linmark Consulting Ltd Hillock, Ballut Street STJ 1373 St Julian's Malta
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Deutschland GmbH, Max-Planck-Strasse 6 27721 RITTERHUDE Germany
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
  • Merck Schuchardt OHG, Eduard-Buchner-Str. 85662 Hohenbrunn Germany
  • MHM Holding GmbH, Feldkirchener Straße 15 D-85551 Kirchheim Germany
  • Nalco Europe B.V., Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands
  • Omnisal GmbH, Dessauerstrasse 128 6886 Lutherstadt Wittenberg Germany
  • Only representative (No publishable name), null
  • Petrokemija d.d. Kutina, Aleja Vukovar 4 HR-44320 Kutina Croatia
  • PFIC Ltd, Pentelis 34 GR 17564 Palaio Faliro, Athens Greece
  • PHOSINT LIMITED, 21 Vasili Michailidi 3026 Limassol Cyprus
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • Praxair Surface Technologies GmbH, Am Muehlbach 13 87487 Wiggensbach Germany
  • PRAYON (OR1) EMAPHOS, 144, rue Joseph Wauters 4480 Engis Belgium
  • PRAYON S.A., 144, rue Joseph Wauters 4480 ENGIS Belgium
  • Przedsiębiorstwo Produkcyjno- Consultingowe ADOB Sp. z o.o. Sp. jawna, Kołodzieja 11 61-070 Poznań Poland Poland
  • Puragen B.V., CIC Rotterdam Stationsplein 45, 3013 AK ROTTERDAM Netherlands
  • Puragen SARL, 132-134 Bd de Verdun Energy Park - Immeuble 7 - 5 ième étage 92400 Courbevoie France
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 Box 5 B-1040 Brussels Belgium
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • sanofi chimie, 82 avenue Raspail 94250 Gentilly France
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • STERIS Ireland Limited, IDA Business and Technology Park Country Offialy R35 X865 Tullamore Ireland
  • Thermphos International B.V., Europaweg Zuid 4, Haven 9890, 4389 PD Ritthem / Vlissingen Netherlands
  • TIMAC AGRO, 27 Avenue Franklin Roosevelt BP 70158 35408 SAINT-MALO France
  • TSGE_2019-006, Im Fliegerhorst 12 38642 Goslar Germany
  • Yara Suomi Oy, Bertel Jumgin aukio 9 FI-02600 Espoo Finland
  • Yordas GmbH, Äußere Nürnberger Straße 62 91301 Forchheim Germany
  • B-Lands Consulting (811575-3), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811649-9), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • Borealis Chimie, 20 ter, rue de BEZONS 92400 COURBEVOIE France
  • CIECH S.A., Wspolna 62 00-684 Warsaw Mazowieckie Poland
  • FMC Foret S.A., Avenida Diagonal 530-532, 3ª planta 08006 Barcelona Spain
  • Lubrizol Europe Coordination Center BVBA 05, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 09, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 16, Chaussee De Wavre 1945 Brussels Belgium
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • SHEMENSAL UK LIMITED, Unit 8, Trade City GU16 7AL Frimley Lyon Way United Kingdom
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • Wacker Chemie AG (OR_WCC), Johannes-Hess-Strasse 24 84489 Burghausen Germany

Substance names and other identifiers

Acide phosphorique
Other
Acido fosforico
Other
Acidum phosphoricum
Other
Evits
Other
Fosforzuuroplossingen
Other
Hydrogen phosphate
Other
o-Phosphoric acid
Other
Orthophosphoric acid
EC Inventory, REACH pre-registration, Other
Orthophosphoric acid
REACH pre-registration, Other, Occupational Exposure Limits - 1st list - Indicative OELVs
phosphoric acid
FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
phosphoric acid ... %, orthophosphoric acid ... %
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
phosphoric acid ... %, orthophosphoric acid ... %
C&L Inventory
Phosphoric acid, ortho-
Other
phosphoric acid, orthophosphoric acid
EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes
PHOSPHORIC ACID, SOLID
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
PHOSPHORIC ACID, SOLUTION
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
Phosphoricum acidum
Other
Phosphorsaeure
Other
Phosphorsaeureloesungen
Other
Sonac
Other
Wc-reiniger
Other
White phosphoric acid
Other
...% fosforo rūgštis, ...% ortofosforo rūgštis (lt)
C&L Inventory
acid fosforic….%, acid ortofosforic….% (ro)
C&L Inventory
acide phosphonique à …, acide orthophosphorique à …% (fr)
C&L Inventory
acido fosforico ... % (it)
C&L Inventory
Fosforhape …%, ortofosforhape …% (et)
C&L Inventory
Fosforihappo... % (fi)
C&L Inventory
fosforjeva kislina…%, ortofosforjeva kislina...% (sl)
C&L Inventory
fosforna kiselina ... %, ortofosforna kiselina ... % (hr)
C&L Inventory
fosforsyra ... % (sv)
C&L Inventory
fosforsyre ... % (da)
C&L Inventory
fosforsyre ... % (no)
C&L Inventory
fosforzuur ... % (nl)
C&L Inventory
foszforsav ...%, ortofoszforsav ...% (hu)
C&L Inventory
kwas fosforowy(V) ... % (pl)
C&L Inventory
kwas ortofosforowy(V) ... % (pl)
C&L Inventory
kyselina fosforečná ... %, kyselina trihydrogenfosforečná ... % (sk)
C&L Inventory
kyselina orthofosforečná ...% (cs)
C&L Inventory
phosphorsyre ... % (da)
C&L Inventory
Phosphorsäure ... % (de)
C&L Inventory
 … % fosforskābe,  … % ortofosforskābe (lv)
C&L Inventory
ácido fosfórico ... % (es)
C&L Inventory
ácido fosfórico em solução ... % (pt)
C&L Inventory
ácido ortofosfórico ... % (es)
C&L Inventory
ορθοφωσφορικό οξύ ... % (el)
C&L Inventory
фосфорна киселина...%, ортофосфорна киселина...% (bg)
C&L Inventory
Phosphoric acid
Other
not available
C&L Inventory
ortho phosphoric acid
C&L Inventory
ortho-phosphoric acid
C&L Inventory
Orthophosphoric aci
C&L Inventory
ORTHOPHOSPHORIC ACID
C&L Inventory, Registration dossier
Orthophosphoric Acid
C&L Inventory, Registration dossier
orthophosphoric acid ... %
C&L Inventory
orthophosphoric acid ...%
C&L Inventory
orthophosphoric acid 75%
C&L Inventory
orthophosphoric acid 85 %
C&L Inventory
ortophosphoric acid
C&L Inventory
phopshoric acid 85%
C&L Inventory
PHOSPHORIC ACID
C&L Inventory, Registration dossier, Other
Phosphoric Acid
C&L Inventory, Registration dossier, Other
phosphoric acid ... %
C&L Inventory
phosphoric acid ... %, orthophosphoric acid
C&L Inventory
phosphoric acid ... %, orthophosphoric acid ... %
C&L Inventory
phosphoric acid ... %, orthophosphoric acid ... %
C&L Inventory
phosphoric acid 75 %
C&L Inventory
phosphoric acid 85%
C&L Inventory
Phosphoric Acid [for General Organic Chemistry]
C&L Inventory
Phosphoric acid, o-Phosphoric acid
Registration dossier
phosphoric acid...%, orthophosphoric acid...%
C&L Inventory
phosphoric acide
C&L Inventory
Phosphoric acod
Registration dossier
Phosphorsäure
C&L Inventory
Phosphorsäure ... %
C&L Inventory
Reaction mass of 1-methoxypropan-2-ol and oxalic acid and sulphuric acid and (2-methoxymethylethoxy)propanol
C&L Inventory
Reaction mass of 64-19-7 and 7697-37-2
C&L Inventory
Reaction mass of ortho-phosphoric aceide, zinc oxide and aluminium oxide
C&L Inventory
Trihydrogenphosphat
C&L Inventory
trihydroxido oxidophosphorus
C&L Inventory
trihydroxidooxidophosphorus
C&L Inventory
Trihydroxidooxidophosphorus Phosphoric acid
C&L Inventory, Registration dossier
4D ACID
Registration dossier
85% phosphoric acid
Registration dossier
Acide orthophosphorique
Registration dossier
Acide phosphorique
Registration dossier
Acido ortofosforico
Registration dossier
Acidum phosphoricum
Registration dossier
Defluorinated acid
Registration dossier
defluorinated phosphoric acid
Registration dossier
DoroFos
C&L Inventory
ETERMER 39
C&L Inventory
Exctractive phosphoric acid
Registration dossier
Green acid
Registration dossier
Hydrogen phosphate
Registration dossier
KFT 41 % potravinářská
Registration dossier
KFT 70 % inhibovaná
Registration dossier
KFT 70 % potravinářská
Registration dossier
KFT 75 % potravinářská
Registration dossier
KFT 80 % potravinářská
Registration dossier
KFT 85 % CP
Registration dossier
KFT 85 % potravinářská
Registration dossier
kwas fosforowy
Registration dossier
kwas fosforowy ekstrakcyjny
Registration dossier
kwas fosforowy odfluorowany
Registration dossier
Kwas ortofosforowy dodatek paszowy
Registration dossier
Kwas ortofosforowy spożywczy
Registration dossier
Kyselina fosforečná potravinářská
Registration dossier
Kyselina fosforečná termická, potravinářská, 80%
Registration dossier
Metaphosphoric acid
Registration dossier
MGA
Registration dossier
monophosphoric acid
Registration dossier
Multi-P 0-58-0(80%)
Registration dossier
Multi-P 0-62-0(85%)
Registration dossier
Multi-P; Multi-P 0-54-0(75%)
Registration dossier
o-Phosphoric acid
Registration dossier
Ortho-Phosphoramide
Registration dossier
ortho-Phosphorsaeure
Registration dossier
Orthophoshoric acid
Registration dossier
Orthophosphate
Registration dossier
Orthophosphoric acid
Registration dossier
P 10-02
Registration dossier
P 10-03
Registration dossier
P 10-04
Registration dossier
P 10-12
Registration dossier
P 10-14
Registration dossier
P 50-03
Registration dossier
PHOSPHORIC ACID
Registration dossier
Phosphoric acid (7CI, 8CI, 9CI)
Registration dossier
Phosphoric acid 75%, 80%, and 85%
Registration dossier
phosphoric acid aqueous
Registration dossier
phosphoric acid solution
Registration dossier
Phosphoric acid thermal inhibited
Registration dossier
phosphoric(V) acid
Registration dossier
Phosphorsaeure
Registration dossier
Phosphorsäure
Registration dossier
PuriPhos
Registration dossier
sodium dihydrogen orthophosphate
Registration dossier
tetraoxophosphoric acid
Registration dossier
trihydrogen tetraoxophosphate(3-)
Registration dossier
trihydroxidooxidophosphorus
Registration dossier
white phosphoric acid
Registration dossier
WPA
Registration dossier
015-011-00-6
Index number
C&L Inventory
1021417-41-3
CAS number
Other
1021417-41-3
Deleted CAS number
Other
1053657-23-0
CAS number
Other
1053657-23-0
Deleted CAS number
Other
1196963-54-8
CAS number
Other
1196963-54-8
Deleted CAS number
Other
1643589-98-3
CAS number
Other
1643589-98-3
Deleted CAS number
Other
178560-73-1
CAS number
Other
178560-73-1
Deleted CAS number
Other
28602-75-7
CAS number
Other
28602-75-7
Deleted CAS number
Other
7664-38-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Active Implantable Medical Devices Directive - Hazardous Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Occupational Exposure Limits - 1st list - Indicative OELVs, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
959699-83-3
CAS number
Other
959699-83-3
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 14 studies submitted
  • 5 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [5]
C Form
Crystalline (60%), Other (40%) [5]
C Odour
Other (100%) [3]
C Substance type
Inorganic (100%) [5]

Type of Study provided
Studies with data
Key study 1
Supporting study 8
Weight of evidence 4
Other 1
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 21 studies submitted
  • 3 studies processed
R Melting / freezing point
41.1 °C @ 101 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 18
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
41.1 °C

Boiling point

Study results
  • 18 studies submitted
  • 3 studies processed
R Boiling point
296.5 °C @ 98.3 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 11 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
296.5 °C

Density

Study results
  • 27 studies submitted
  • 1 study processed
R Relative density
1.84 @ 38 °C [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 17 7
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 24 studies submitted
  • 10 studies processed
R Vapour pressure
2.933 - 4 Pa @ 20 - 25 °C [10]

Type of Study provided
Studies with data
Key study
Supporting study 13 1
Weight of evidence 6 4
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
4 Pa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 12 studies submitted
  • 6 studies processed
R Water solubility (mass/vol.)
850 g/L @ 20 °C and pH 0.5 [6]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 12
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Water solubility
1 000 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 15 studies submitted
  • 15 studies processed
C Dissociating properties
Yes (100%) [15]
R Dissociation constant
2.12 - 12.38 @ 20 - 25 °C [27]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 9 6
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 21 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 13 5
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 3 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 21 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 16 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 2
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 9 studies submitted
  • 3 studies processed
P/RResults
EC50 (48 h) 100 mg/L [3]
NOEC (48 h) 56 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 2
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 3 studies processed
P/RResults
EC50 (72 h) 100 mg/L [3]
NOEC (72 h) 100 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
EC50 for freshwater algae
100 mg/L
EC10 or NOEC for freshwater algae
100 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 1 g/L [1]
NOEC (3 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 3 summaries submitted
  • 1 summary processed
EC50 for microorganisms
1 g/L
EC10 or NOEC for microorganisms
1 g/L

Sediment toxicity

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 2
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 2
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 2
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 2
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 2
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons. 2
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 10.7 mg/m³ repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: (DNEL) 1 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 2 mg/m³ -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.57 mg/m³ repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: (DNEL) 360 µg/m³ skin irritation/corrosion
Acute /short term: Medium hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary)
Acute /short term: Hazard unknown (no further information necessary)
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 100 µg/kg bw/day repeated dose toxicity
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 100 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 30 studies submitted
  • 2 studies processed
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 20 1
Weight of evidence 7
Other
Data waiving
no waivers
inhalation
  • 9 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 4 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
dermal
  • 15 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 67 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 59 2
Weight of evidence 3
Other 1
Data waiving
no waivers
Study data: eye
  • 46 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 41 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Skin sensitisation
No study available
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 48 studies submitted
  • 2 studies processed
P/RResults
NOAEL (dog): 322.88 - 492.77 mg/kg bw/day [2]
LOAEL (rat): 155 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 4 2
Supporting study 12 19
Weight of evidence
Other 11
Data waiving
no waivers
Study data: inhalation
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Study data: dermal
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 155 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 9
Supporting study 12
Weight of evidence
Other 1
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
Study data: developmental
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2 2 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 370 mg/kg bw/day (chronic, mouse)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant