Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
225-208-0
CAS no.:
4719-04-4
Index number:
613-114-00-6
Molecular formula:
C9H21N3O3
SMILES:
OCCN1CN(CCO)CN(CCO)C1
InChI:
InChI=1S/C9H21N3O3/c13-4-1-10-7-11(2-5-14)9-12(8-10)3-6-15/h13-15H,1-9H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
12
Of which contain:
9 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is harmful if swallowed and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is fatal if inhaled, causes severe skin burns and eye damage, causes damage to organs through prolonged or repeated exposure, causes serious eye irritation and may cause respiratory irritation.

Breakdown of all 1454 C&L notifications submitted to ECHA

Acute Tox. 4 H302 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Acute Tox. 2 H330
STOT RE 1 H372
Eye Irrit. 2 H319
Acute Tox. 3 H331
STOT SE 3 H335
Not Classified
Acute Tox. 3 H311
Skin Corr. 1 H314
Skin Corr. 1B H314
STOT RE 2 H373
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss*
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations). A majority of data submitters indicating this property of concern indicate that it may relate to an impurity / additive rather than the substance itself.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 14 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation, preservation for liquid systems, controlling slimes, preservation for working / cutting fluids.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: laboratory chemicals.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of substance into small containers.

Other release to the environment of this substance is likely to occur from: indoor use as reactive substance.

This substance is used in the following products: pH regulators and water treatment products.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, transfer of chemicals at dedicated facilities, closed, continuous processes with occasional controlled exposure, laboratory work, mixing in open batch processes, transfer of substance into small containers and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and of substances in closed systems with minimal release.

This substance is used in the following products: fuels, oil and gas exploration or production products, pH regulators and water treatment products and water treatment chemicals.

This substance is used in the following areas: mining. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, transfer of chemicals at dedicated facilities, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: of substances in closed systems with minimal release, as processing aid, manufacturing of the substance and in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: transfer of chemicals at dedicated facilities, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, of substances in closed systems with minimal release, in processing aids at industrial sites and as processing aid.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Abbott Diagnostics GmbH, Max Planck Ring 2 D-65205 Delkenheim Hessen Germany
  • Bakelite Oy, Teollisuustie 20 B 82430 Puhos Finland
  • Baker Hughes (Nederland) B.V , p/a Blokmakersweg 10 1786 RC den Helder Netherlands
  • Blue Frog Scientific EURL EU OR9, 967 Route de la Plaine La Plaine 26400 Chabrillan France
  • ChampionX Europe BV, Oude Rhijnhofweg 17 Oegstgeest 2342BB Leiden Netherlands
  • Domus Chemicals S.p.A, v. Mazzini 1 24066 Pedrengo Bergamo Italy
  • EcoMundo, 195 Rue Jean Jacques Rousseau 92130 Issy-les-Moulineaux France
  • L.A.C.S.A. SRL, strada antica di Alpignano 46 IT-10090 Rosta Piemonte Italy
  • Lamberti S.p.A., via Piave 18 21041 Albizzate Varese Italy
  • TROY CHEMICAL COMPANY BV, Poortweg 4C 2612PA Delft Netherlands
  • Troy Moerdijk BV, Westelijke randweg 9 4791 RT Klundert Netherlands
  • Troy Rheinland GmbH, Industriepark 23 56593 Horhausen Germany
  • Veolia Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • [Confidential], [Confidential]
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany

Substance names and other identifiers

1,3,5-Triazine-1,3,5(2H,4H,6H)-triethanol
2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol 1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
C&L Inventory
2,2',2''-(hexahydro-1,3,5- triazine-1,3,5-triyl)triethanol;1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
EC Inventory, REACH pre-registration
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
Substance Evaluation - CoRAP, REACH pre-registration
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5- triyl)triethanol (HHT)
Biocidal active substances
hexahydro-1 3,5-tris(hydroxyethyl)-s-triazine (N-formal)
Other
Triazinetriethanol
Other
1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazin (HHT) (cs)
Biocidal active substances
2,2',2"-(esaidro-1,3,5-triazin-1,3,5-triil)trietanolo (it)
C&L Inventory
2,2',2"-(heksahydro-1,3,5-triatsiini-1,3,5-triyyli)trietanoli (fi)
C&L Inventory
2,2',2"-(hexahidro-1,3,5-triazina-1,3,5-triil)trietanol (es)
C&L Inventory
2,2',2"-(hexahidro-1,3,5-triazina-1,3,5-triil)trietanol (pt)
C&L Inventory
2,2',2"-(hexahidro-1,3,5-triazina-1,3,5-triil)trietanol 1,3,5-tris(2-hidroxietil)hexahidro-1,3,5-triazine (ro)
C&L Inventory
2,2',2"-(hexahydro-1,3,5-triazin-1,3,5-triyl)trietanol 1,3,5-tris(2-hydroxietyl)-1,3,5-triazin (sv)
C&L Inventory
2,2',2"-(hexahydro-1,3,5-triazin-1,3,5-triyl)triethanol (da)
C&L Inventory
2,2',2"-(Hexahydro-1,3,5-triazin-1,3,5-triyl)triethanol 1,3,5-Tris(2-hydroxyethyl)hexahydro-1,3,5-triazin (de)
C&L Inventory
2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol (nl)
C&L Inventory
2,2',2"-(hexahydro-1,3,5-triazín-1,3,5-triyl)trietanol 1,3,5-tris(2-hydroxyetyl)hexahydro-1,3,5-triazín (sk)
C&L Inventory
2,2',2"-(хексахидро-1,3,5-триазин-1,3,5-триил)триетанол 1,3,5-трис(2-хидроксиетил)хексахидро-1,3,5-триазин (bg)
C&L Inventory
2,2',2"-heksahidro-1,3,5-triazan-1,3,5-triil)trietanolis 1,3,5-tri(2-hidroksietil)heksahidro-1,3,5-triazinas (lt)
C&L Inventory
2,2',2''-(heksahidro-1,3,5-triazin-1,3,5-triil)trietanol 1,3,5-tris(2-hidroksietil)heksahidro-1,3,5-triazin (sl)
C&L Inventory
2,2',2''-(heksahidro-1,3,5-triazīn-1,3,5-triil)trietanols 1,3,5-tris(2-hidroksietil)heksahidro-1,3,5-triacīns (lv)
C&L Inventory
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triéthanol;1,3,5-tris(2-hydroxyéthyl)hexahydro-1,3,5-triazine (fr)
C&L Inventory
2,2',2:-(εξαϋδρο-1,3,5-τριαζινο-1,3,5-τριυλο)τριαιθανόλ (el)
C&L Inventory
2,2`,2``-(heksahydro-1,3,5-triazyno-1,3,5-triylo)trietanol 1,3,5-tris(2-hydroksyetylo)heksahydro-1,3,5-triazyna (pl)
C&L Inventory
2,2´,2´´-heksahüdro-1,3,5-triasiin-1,3,5-triüül)trietanool 1,3,5-tris(2-hüdroksüetüül)heksahüdro-1,3,5-trasiin (et)
C&L Inventory
2,2’,2”-(hexahidro-1,3,5-triazin-1,3,5-triil)trietanol 1,3,5-trisz(2-hidroxietil)hexahidro-1,3,5-triazin (hu)
C&L Inventory
2,2′,2′′-(esaidro-1,3,5-triazin 1,3,5-triil)trietanolo (HHT) (it)
Biocidal active substances
2,2′,2′′-(Eżaiidro-1,3,5-triażin-1,3,5-triil)trietanol (HHT) (mt)
Biocidal active substances
2,2′,2′′-(heksahidro-1,3,5-triazin-1,3,5- triil)trietanol (HHT) (hr)
Biocidal active substances
2,2′,2′′-(heksahidro-1,3,5-triazin-1,3,5-triil)trietanol (HHT) (sl)
Biocidal active substances
2,2′,2′′-(heksahidro-1,3,5-triazin-1,3,5-triil)trietanolis (HHT) (lt)
Biocidal active substances
2,2′,2′′-(Heksahidro-1,3,5-triazīn-1,3,5-triil)trietanols (HHT) (lv)
Biocidal active substances
2,2′,2′′-(heksahydro-1,3,5-triatsiini-1,3,5-triyyli)trietanoli (HHT) (fi)
Biocidal active substances
2,2′,2′′-(heksahüdro-1,3,5-triasiin-1,3,5-triüül)trietanool (HHT) (et)
Biocidal active substances
2,2′,2′′-(hexa-hidro-1,3,5-triazina-1,3,5-triil)trietanol (HHT) (pt)
Biocidal active substances
2,2′,2′′-(hexahidro-1,3,5-triazin-1,3,5-triil)trietanol (HHT) (hu)
Biocidal active substances
2,2′,2′′-(hexahidro-1,3,5-triazin-1,3,5-triil)trietanol (HHT) (ro)
Biocidal active substances
2,2′,2′′-(Hexahidro-1,3,5-triazina-1,3,5-triil)trietanol (HHT) (es)
Biocidal active substances
2,2′,2′′-(hexahydro-1,3,5-triazin-1,3,5-triyl)trietanol (HHT) (sv)
Biocidal active substances
2,2′,2′′-(Hexahydro-1,3,5-triazin-1,3,5-triyl)triethanol (HHT) (de)
Biocidal active substances
2,2′,2′′-(Hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol (HHT) (nl)
Biocidal active substances
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol (HHT) (no)
Biocidal active substances
2,2′,2′′-(hexahydro-1,3,5-triazín-1,3,5-triyl)trietanol (HHT) (sk)
Biocidal active substances
2,2′,2′′-(εξαϋδρο-1,3,5-τριαζινο-1,3,5-τριυλο)τριαιθανόλη (HHT) (el)
Biocidal active substances
2,2′,2′′-(хексахидро-1,3,5-триазин-1,3,5-триил)триетанол (HHT) (bg)
Biocidal active substances
2,2′,2″-(heksahydro-l,3,5-triazyn-l,3,5-triylo)trietanol (HHT) (pl)
Biocidal active substances
2,2′,2″-(hexahydro-1,3,5-triazin-1,3,5-triyl)triethanol (HHT) (da)
Biocidal active substances
2,2′,2″-(hexahydro-1,3,5-triazine-1,3,5-triyl)triéthanol (HHT) (fr)
Biocidal active substances
hexahydro-1,3,5-triazin-1,3,5-triethanol 1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazin (cs)
C&L Inventory
1,3,5-Triazine-1,3,5(2H,4H,6H)-triethanol
C&L Inventory
1,3,5-Tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
C&L Inventory, Registration dossier
1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine 2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
C&L Inventory
2,2',2"-(1,3,5-triazinane-1,3,5-triyl)triethanol
Registration dossier
2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
C&L Inventory
2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
Registration dossier
2,2',2"-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol;
C&L Inventory
2,2',2''-(1,3,5-triazinane-1,3,5-triyl)triethanol
C&L Inventory, Registration dossier
2,2',2''-(HEXAHYDRO-1,3,5-TRIAZINE-1,3,5-TRIYL)TRIETHANOL
C&L Inventory, Registration dossier
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
C&L Inventory, Registration dossier
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol (IUC4 D SN 432) / 2,2',2''-(1,3,5-triazinane-1,3,5-triyl)triethanol / HHT
Registration dossier
2,2',2''-(Hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol; 1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
C&L Inventory
2,2,2"-(Hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
C&L Inventory
2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethan-1-ol
C&L Inventory, Other
2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanol
C&L Inventory, Other
2-[4,6-bis(2-hydroxyethyl)-1,3,5-triazinan-2-yl]ethanol
C&L Inventory
MELA Triazine
Registration dossier
MELA Triazine, HHT
Registration dossier
S-TRIAZINE-1,3,5(2H,4H,6H)-TRIETHANOL
C&L Inventory
Triadine 10
C&L Inventory
triazinane-1,3,5-triethanol
C&L Inventory
1,3,5-Triazine-1,3,5(2H,4H,6H)-triethanol (9CI)
Registration dossier
1,3,5-Tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
Registration dossier
1,3,5-Tris(2-hydroxyethyl)hexahydro-s-triazine
Registration dossier
1,3,5-Tris-(2-hydroxyethyl)-1,3,5-hexahydrotriazine (chemical name)
Registration dossier
Grotan
Registration dossier
Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine
Registration dossier
Hexahydrotriazine
C&L Inventory
Hexahydrotriazine (common name)
Registration dossier
HHT (abbreviation)
Registration dossier
MELA Triazine
Registration dossier
MELA Triazine (Acroym)
Registration dossier
N,N',N''-Tris(2-hydroxyethyl)hexahydro-s-triazine
Registration dossier
Nuosept 78
Registration dossier
Prosweet
Registration dossier
Protectol
Registration dossier
Protectol HT
Registration dossier
s-Triazine-1,3,5(2H,4H,6H)-triethanol (8CI)
Registration dossier
Scavtreat
Registration dossier
SYNTAN OXB
Registration dossier
T00W1
Registration dossier
TIS # O1644
Registration dossier
252849-78-8
CAS number
Other
4719-04-4
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Biocidal active substances, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
613-114-00-6
Index number
C&L Inventory
63310-09-8
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Viscous (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)
Form
Liquid: viscous (100%)
Colour
colourless (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-79 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-79 °C

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
110.1 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
110.1 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
1 140.2 - 1 154.9 @ 20 - 40 °C [3]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.155

Vapour pressure

Study results
  • 4 studies submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
-2.3 - -1.3 @ 24 °C and pH 5 - 9 [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-2 @ 24 °C

Water solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
99.1 - 412 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
412 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
47.6 min [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
47 min

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 1 study processed
R Koc
10 L/kg @ 25 °C [1]
R log Koc
1 dimensionless @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
10

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 6.6 µg/L (1)
Intermittent releases (freshwater) 6.6 µg/L (1)
Marine water 660 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 5.5 mg/L (1)
Sediment (freshwater) 30.4 µg/kg sediment dw (1)
Sediment (marine water) 3.04 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 2.19 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 16.07 - 240.04 mg/L [2]
LC0 (4 days) 5 mg/L [1]
LC100 (4 days) 58.9 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 11.9 mg/L [1]
LC50 (48 h) 60.67 mg/L [1]
EC0 (48 h) 8.75 mg/L [1]
EC100 (48 h) 17.5 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (72 h) 6.66 - 21 mg/L [3]
NOEC (72 h) 1.56 - 10 mg/L [2]
LOEC (72 h) 3.13 mg/L [1]
EC10 (72 h) 3.4 mg/L [1]
EC90 (72 h) 10.4 - 29.8 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
6.6 mg/L
EC50 for marine water algae
21 mg/L
EC10 or NOEC for freshwater algae
3.4 mg/L
EC10 or NOEC for marine water algae
10 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (30 min) 550 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
550 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for marine water sediment
875.47 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 200 µg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 1 study processed
P/RResults
LD50 1 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Category 4 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 1
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 338 - 400 mg/m³ air (rat) [3]
M/CInterpretations of results
Category 2 based on GHS criteria [1]

inhalation
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 5 studies submitted
  • 1 study processed
P/RResults
LD50 4 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 1
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 1 000 mg/kg bw
Inhalation route:
Adverse effect observed LC50 371 mg/m³ air
Dermal route:
No adverse effect observed Discriminating dose 4 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence 1
Other 1
Data waiving
no waivers
Study data: eye
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 1 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other 1 3
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 64.1 - 91 mg/kg bw/day [1]
LOAEL (rat): 285.2 - 338.6 mg/kg bw/day [1]
NOEL (rat): 14.1 - 21.1 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEC (rat): 30 mg/m³ air [1]
LOAEC (rat): 3 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 64 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 30 mg/m³ (subacute, rat)
Inhalation route - local effects:
Adverse effect observed LOAEC 3 mg/m³ (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 3
Weight of evidence
Other 3 2
Data waiving
no waivers
Study data: in vivo
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant