Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
215-239-8
CAS no.:
1314-62-1
Index number:
023-001-00-8
Molecular formula:
SMILES:
InChI:
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
17
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP18) approved by the European Union, this substance is fatal if inhaled, is toxic if swallowed, may cause cancer, causes damage to organs through prolonged or repeated exposure, is toxic to aquatic life with long lasting effects, is suspected of causing genetic defects, is suspected of damaging fertility and the unborn child, may cause harm to breast-fed children and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes serious eye damage.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is very toxic to aquatic life.

Breakdown of all 811 C&L notifications submitted to ECHA

Muta. 2 H341 Harmonised Classification
Repr. 2 H361fd Harmonised Classification
Aquatic Chronic 2 H411 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
STOT RE 1 H372 Harmonised Classification
Acute Tox. 4 H332
Acute Tox. 4 H302
Eye Dam. 1 H318
Acute Tox. 3 H301 Harmonised Classification
Acute Tox. 2 H330 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Lact. H362 Harmonised Classification
Aquatic Acute 1 H400
Acute Tox. 2 H300
STOT RE 2 H372
https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • M
Suspected to be Mutagenic (Harmonised C&L).
  • R
Suspected to be Toxic to Reproduction (Harmonised C&L).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 37 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: vehicles, electrical batteries and accumulators and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: laboratory chemicals.

This substance is used in the following areas: scientific research and development and formulation of mixtures and/or re-packaging.

This substance is used in the following activities or processes at workplace: mixing in open batch processes, transfer of substance into small containers, laboratory work and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: pH regulators and water treatment products, fertilisers, laboratory chemicals, washing & cleaning products, water treatment chemicals and metals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and manufacturing of the substance.

This substance is used in the following products: pH regulators and water treatment products, laboratory chemicals, fertilisers, washing & cleaning products and water treatment chemicals.

This substance is used in the following areas: health services. This substance is used for the manufacture of: chemicals and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, manual maintenance (cleaning and repair) of machinery, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, in the production of articles and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders) and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: avoid release to the environment; do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Get medical advice/attention if you feel unwell. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AFFILIPS NV, Biezenstraat 26-31 3300 Tienen Belgium
  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • Argo Capital B.V., Stationspark 600 3364DA Sliedrecht Netherlands
  • BASF Catalysts Germany GmbH, Seligmannallee 1 30173  Hannover Germany
  • BASF Nederland B.V., Velperplein 23 6811 AH Arnhem Netherlands
  • BASF Polska Sp.z o.o., Al. Jerozolimskie 142B 02-305 Warszawa Polska Poland
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas Road, Dublin D12 XV7K Dublin Ireland
  • CellMark Deutschland GmbH, Parsevalstraße 9A D - 40468 Düsseldorf Germany Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
  • Czech Vanadium, a.s., 252 10 Mniske pod Brdy 252 10 Mniske pod Brdy Czech Republic
  • ERASTEEL, Tour Maine Montparnasse 33 Avenue du Maine 75755 PARIS Cedex 15 France
  • Euro Support Advanced Materials B.V., Liessentstraat 9f 5405 AH Uden Netherlands
  • GfE Metalle und Materialien GmbH, Hoefener Str. 45 90431 Nuernberg Bavaria Germany
  • Glencore Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • H.C. Starck Tungsten GmbH, Im Schleeke 78-91 38642 Goslar Germany
  • Haldor Topsoe A/S, Nymøllevej 50 DK28000 Lyngby Denmark
  • Hulteberg Chemistry & Engineering, Rödklintsgatan 2 B 21873 Tygelsjö Sweden
  • Largo Commodities Trading Limited, Haddington Road 2nd Floor, 1-2 Victoria Buildings D04 XN32 Dublin Ireland
  • MECS Europe/Africa BV, I. Vandammestraat 7, Building B 1560 Hoeilaart Belgium
  • MSSA, Pombliere 73600 Saint Marcel France
  • Only representative (No publishable name), null
  • Pangang Europe GmbH, Rheinallee 165 40545 Düsseldorf Germany
  • POLYNT S.p.A., via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy
  • SC48 London Chemicals & Resources Ltd, Długosza 67 43-188 Orzesze Poland
  • SETURAL TRADING BV, Blaak 40, Fifth floor 3011 TA Rotterdam Netherlands
  • SGS EWACS NV 16, Keetberglaan 4 Haven 1091 9120 Melsele Antwerp Belgium
  • SHELL CATALYSTS & TECHNOLOGIES BELGIUM, Pantserschipstraat 331 9000 Gent Belgium
  • Steptoe & Johnson LLP, Av Louise, 489 1050 Brussels Belgium
  • TODINI AND CO. SPA, Corso Milano 46 B 20900 MONZA ITALIA Italy
  • TODINI BV, Kleine Pathoekeweg 82 B-8000 Brugge Belgium
  • Traxys Europe SA, 19-21 Route Arlon same L-8009 Strassen Luxembourg Luxembourg
  • Treibacher Industrie AG, Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria
  • TSGE_2019-008, Im Fliegerhorst 12 38642 Goslar Germany
  • AD International BV, Markweg Zuid 27 4794 SN Heijningen Noord-Brabant Netherlands
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • Steptoe & Johnson LLP, Av Louise, 489 1050 Brussels Belgium

Substance names and other identifiers

Divanadium pentaoxide
EC Inventory, REACH pre-registration
Divanadium pentaoxide
REACH pre-registration, Cosmetic Products Regulation, Annex II - Prohibited Substances
divanadium pentaoxide; vanadium pentoxide
C&L Inventory, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Vanadium pentoxide
Other
VANADIUM PENTOXIDE, non-fused form
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
divanaadiumpentaoksiid; vanaadiumpentoksiid (et)
C&L Inventory
divanadijev pentaoksid; vanadijev pentoksid (sl)
C&L Inventory
divanadijev pentoksid; vanadijev pentoksid (hr)
C&L Inventory
divanadinpentoxid; vanadinpentoxid (sv)
C&L Inventory
divanadiumpentaoxid; vanadiumpentaoxid (da)
C&L Inventory
Divanadiumpentaoxid; Vanadiumpentoxid (de)
C&L Inventory
divanadiumpentaoxide; vanadiumpentaoxide (nl)
C&L Inventory
divanadiumpentoksid vanadiumpentoksid (no)
C&L Inventory
divanadiumpentoksidi; vanadiumpentoksidi (fi)
C&L Inventory
divanadžio pentoksidas; vanadžio pentoksidas (lt)
C&L Inventory
divanádium-pentoxid; vanádium-pentoxid (hu)
C&L Inventory
divanādija pentaoksīds; vanādija pentoksīds (lv)
C&L Inventory
oxid vanadičný (cs)
C&L Inventory
oxid vanadičný; oxid vanadičný (sk)
C&L Inventory
pentaossido di divanadio vanadio pentossido (it)
C&L Inventory
pentaossidu tad-divanadju; pentossidu tal-vanadju (mt)
C&L Inventory
pentaoxid de divanadiu; pentoxid de vanadiu (ro)
C&L Inventory
pentaoxyde de divanadium; pentoxyde de vanadium (fr)
C&L Inventory
pentatlenek diwanadu; pentatlenek wanadu (pl)
C&L Inventory
Pentaóxido de divanadio; pentaóxido de vanadio (es)
C&L Inventory
pentóxido de divanádio; pentóxido de vanádio (pt)
C&L Inventory
πεντοξείδιο του διβαναδίου· πεντοξείδιο του βαναδίου (el)
C&L Inventory
диванадиев пентаоксид; ванадиев пентаоксид (bg)
C&L Inventory
[(dioxovanadio)oxy]dioxovanadium
C&L Inventory
dioxovanadiooxy(dioxo)vanadium
Other
Divanadium Pentaoxide
C&L Inventory, Registration dossier
Divanadium pentaoxide
C&L Inventory, Registration dossier
divanadium pentaoxide, V2O5
Registration dossier
Divanadium pentaoxide; vanadium pentoxide
C&L Inventory
Divanadium pentoxide
C&L Inventory, Registration dossier
divanadium(5+) pentaoxidandiide
Other
Divanadium_Pentaoxide
Registration dossier
Divannadium Pentoxide
C&L Inventory
London Chemicals + Resources Ltd
Registration dossier
Pentaoxyde de divanadium
C&L Inventory
V2O5
C&L Inventory
Vanadium
C&L Inventory
Vanadium pentaoxide
Registration dossier
vanadium pentaoxide
Registration dossier
vanadium pentoxide
C&L Inventory, Registration dossier
Vanadium Pentoxide
Registration dossier
Vanadium(V) Oxide
C&L Inventory
vanadiumpentoxide
C&L Inventory
Vanadium Pentoxide
Registration dossier
Vanadium pentoxide fused flakes
Registration dossier
023-001-00-8
Index number
C&L Inventory
12503-98-9
CAS number
Other
1314-62-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
1408062-28-1
CAS number
Other
166165-37-3
CAS number
Other
172928-47-1
CAS number
Other
184892-22-6
CAS number
Other
200577-85-1
CAS number
Other
203812-34-4
CAS number
Other
2142684-30-6
CAS number
Other
251927-12-5
CAS number
Other
410546-90-6
CAS number
Other
56870-07-6
CAS number
Other
581075-33-4
CAS number
Other
828264-64-8
CAS number
Other
854372-97-7
CAS number
Other
857777-38-9
CAS number
Other
863639-26-3
CAS number
Other
87854-55-5
CAS number
Other
87854-56-6
CAS number
Other
934750-46-6
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Crystalline (50%), Flakes (25%), Powder (25%) [4]
C Odour
Odourless (50%), Other (50%) [2]
C Substance type
Inorganic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)
Form
Solid: crystalline (100%)
Colour
brown (50%), yellow (50%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 3 studies processed
R Melting / freezing point
681 - 690 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
681 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Density
3.65 g/cm³ @ 21.7 °C [1]
R Relative density
3.65 @ 21.7 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
3.65

Vapour pressure

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
515 - 920 mg/L @ 20 °C and pH 2.7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
920 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 26 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 6
Weight of evidence 17
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
12.3 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 22 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study 11
Weight of evidence 1
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 17.8 µg/L (1)
Intermittent releases (freshwater) 6.93 µg/L (1)
Marine water 2.5 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 450 µg/L (1)
Sediment (freshwater) 563 mg/kg sediment dw (1)
Sediment (marine water) 79 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 7.2 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 167 µg/kg food (1)

Short–term toxicity to fish

Study results
  • 26 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 693 - 27 800 µg/L [2]
LC50 (72 h) 732 - 27 800 µg/L [2]
LC50 (48 h) 1.398 - 30.7 mg/L [2]
LC50 (24 h) 9.005 - 44 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 15
Weight of evidence
Other 9
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 9 studies submitted
  • 4 studies processed
P/RResults
NOEC (3.2 months) 1.5 mg/L [1]
NOEC (3.167 months) 1.5 mg/L [1]
NOEC (70 days) 480 µg/L [1]
NOEC (30 days) 41 µg/L [1]
NOEC (28 days) 120 - 480 µg/L [4]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 4
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 13 studies submitted
  • 2 studies processed
P/RResults
LC50 (48 h) 1.52 - 13.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 15 studies submitted
  • 11 studies processed
P/RResults
NOEC (3.267 months) 560 - 1 000 µg/L [2]
NOEC (28 days) 6.137 - 15.6 mg/L [2]
NOEC (23 days) 1.344 - 1.6 mg/L [2]
NOEC (14 days) 211 µg/L [1]
NOEC (48 h) 25 - 750 µg/L [6]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 11
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 11 studies submitted
  • 8 studies processed
P/RResults
EC50 (72 h) 989.4 - 8 000 µg/L [14]
NOEC (72 h) 16.8 - 4 130 µg/L [9]
EC10 (72 h) 220 - 5 720 µg/L [11]
EC20 (72 h) 1.69 - 1.72 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 8
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
2.907 mg/L
EC10 or NOEC for freshwater algae
270 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (7 days) 21.9 - 49.2 mg/L [4]
NOEC (7 days) 1.25 - 13.5 mg/L [4]
LOEC (7 days) 4.17 - 44.2 mg/L [4]
EC10 (7 days) 7.7 - 16.7 mg/L [4]
EC20 (7 days) 11.3 - 24.2 mg/L [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
34.4 mg/L
EC10 or NOEC for freshwater plants
12.8 mg/L

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 100 mg/L [1]
EC10 (3 h) 4.5 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
4.5 mg/L

Sediment toxicity

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC10 (56 days) 22 mg/kg soil dw [1]
EC10 (28 days) 2 - 81 mg/kg soil dw [6]
EC10 (28 days) 54 mg/kg soil ww [1]
LC50 (28 days) 340 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC10 (28 days) 3 - 492 mg/kg soil dw [6]
NOEC (28 days) 96 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 13 studies submitted
  • 5 studies processed
P/RResults
NOEC (45 days) 97 - 110 mg/kg soil dw [4]
NOEC (28 days) 28 mg/kg soil dw [5]
EC10 (14 days) 11 - 180 mg/kg soil dw [16]
EC10 (5 days) 24 - 370 mg/kg soil dw [8]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other 8
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 8 studies submitted
  • 4 studies processed
P/RResults
NOEC (28 days) 3.2 - 122 mg/kg soil dw [3]
NOEC (21 days) 122 mg/kg soil dw [1]
NOEC (24 h) 3.2 - 1 650 mg/kg soil dw [2]
EC10 (28 days) 35 - 960 mg/kg soil dw [7]
EC10 (7 days) 14 - 350 mg/kg soil dw [7]

Type of Study provided
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 18 studies submitted
  • 1 study processed
P/RResults
NOEC (28 days) 5 mg/kg diet [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 17
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
5 mg/kg food

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 140 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 700 µg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 90 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 450 µg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 140 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 700 µg/kg bw/day repeated dose toxicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study 1 6
Weight of evidence 1 7
Other 1
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 16 %
Dermal: 0.1 %
Inhalation: 10.1 %

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 3 studies processed
P/RResults
LD50 221.1 - 715.7 mg/kg bw (rat) [6]
M/CInterpretations of results
Category 3 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 3 studies processed
P/RResults
LC50 (4 h) 2.21 - 16.19 mg/L air (rat) [6]
LC0 (4 h) 1.62 - 5.2 mg/L air (rat) [6]
M/CInterpretations of results
Category 4 based on GHS criteria [3]

inhalation
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 3 studies submitted
  • 3 studies processed
P/RResults
LD50 2 500 mg/kg bw (rat) [6]
M/CInterpretations of results
GHS criteria not met [3]

dermal
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 467 mg/kg bw
Inhalation route:
Adverse effect observed LC50 4.29 mg/L air
Dermal route:
No adverse effect observed Discriminating dose 2 500 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irreversible damage)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 19 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 16.9 mg/kg bw/day [1]
NOAEL (rat): 750 mg/L drinking water [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 13 2
Weight of evidence 4
Other
Data waiving
no waivers
Study data: inhalation
  • 12 studies submitted
  • 3 studies processed
P/RResults
NOAEC (rat): 1 mg/m³ air [1]
NOAEC (mouse): 231 mg/m³ air [1]
LOAEC (rat): 2 mg/m³ air [1]
LOAEC (mouse): 1.03 mg/L air [1]

Study data: inhalation
Studies with data
Key study 3
Supporting study 7
Weight of evidence 2
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - local effects:
Adverse effect observed LOAEC 500 µg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 30 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 18
Other 12
Data waiving
no waivers
Study data: in vivo
  • 23 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 5
Supporting study 3
Weight of evidence
Other 15
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 2
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route:
Adverse effect observed LOAEC 500 µg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 23 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 7
Weight of evidence
Other 12 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 2 1
Weight of evidence 3 1
Other 4 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
Adverse effect observed NOAEC 4 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 3
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant