Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
215-231-4
CAS no.:
1314-35-8
Index number:
Molecular formula:
O3W
SMILES:
O=[W](=O)=O
InChI:
InChI=1S/3O.W
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
13
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is harmful if swallowed, causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Breakdown of all 786 C&L notifications submitted to ECHA

Acute Tox. 4 H302
Eye Irrit. 2 H319
Skin Irrit. 2 H315
STOT SE 3 H335
Not Classified
Acute Tox. 4 H312
Acute Tox. 4 H332
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Nanomaterial form

Substance is known to be on the EEA market in nanomaterial form, as listed in the EUON Nanomaterials in the EU market list.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 47 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:
Nanomaterials in the EU Market

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: coating products.

Other release to the environment of this substance is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following activities or processes at workplace: potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), transfer of chemicals and laboratory work.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).

This substance is used in the following products: coating products, metals, metal surface treatment products and laboratory chemicals.

This substance is used for the manufacture of: mineral products (e.g. plasters, cement), fabricated metal products and .

This substance is used in the following activities or processes at workplace: transfer of chemicals, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and laboratory work.

Other release to the environment of this substance is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: laboratory chemicals, coating products, textile treatment products and dyes and pH regulators and water treatment products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of substance into small containers, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders) and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following products: pH regulators and water treatment products, metals and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals and metals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, manufacturing of the substance and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Advanced Refining Technologies GmbH, In der Hollerhecke 1 67547 Worms Germany
  • Advanced Refining Technologies Srl, Via Trento 7 20017 Passirana di Rho (MI) Italy
  • ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
  • AVAS COMMODITIES LIMITED, 2ND FLOOR, SHREWSBURY HOUSE, OLD BRAY ROAD CABINTEELY 18 Dublin Ireland
  • AXENS SA, 89, boulevard Franklin Roosevelt B.P. 50802 F-92508 Rueil-Malmaison Cedex France France
  • B-Lands Consulting (811554-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811719-3), 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • BASF Polska Sp.z o.o., Al. Jerozolimskie 142B 02-305 Warszawa Polska Poland
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BLUESTONE METALS & CHEMICALS EUROPE S.L., c/ Pascual y Genis 1 46002 Valencia Spain
  • Buss & Buss Spezialmetalle GmbH, Sassnitzer Strasse 10 18551 Sagard Germany
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas Road, Dublin D12 XV7K Dublin Ireland
  • CATALYST RECOVERY EUROPE S.A., 420, Route de Longwy 4832 Rodange Luxembourg
  • Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
  • CRYTUR, spol. s r.o., Na Lukách 2283 51101 Turnov Czech Republic
  • ECO-RIGEN S.R.L., Contrada Piana del Signore c/o Gela Refinery 93012 Gela Italy
  • Eurecat Deutschland GmbH, Tricatstrasse 06803 Bitterfeld-Wolfen Saxonia-Anhalt Germany
  • EURECAT FRANCE SAS, 121 ave Marie Curie ZI Jean Jaurès 07800 La Voulte sur Rhône France
  • Euro Support Advanced Materials B.V., Liessentstraat 9f 5405 AH Uden Netherlands
  • Euro Support Manufacturing Czechia, s.r.o., Záluží 1 436 70 Litvínov Czech Republic
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • Global Tungsten & Powders spol. s r.o., Zahradni 46 79201 Bruntal Czech Republic
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • H.C. Starck Tungsten GmbH, Im Schleeke 78-91 38642 Goslar Germany
  • Haldor Topsoe A/S, Nymøllevej 50 DK28000 Lyngby Denmark
  • IBU-tec Advanced Materials AG, Hainweg 9-11 D-99425 Weimar Germany
  • ITACA, S.A., Partida Rambleta s/n 12191 Pobla Tornesa Castellón Spain
  • Johnson Matthey Catalysts (Germany) GmbH, Bahnhofstrasse 43 D-96257 Redwitz Germany
  • Johnson Matthey Chemicals GmbH (OR), Wardstraße 17 46446 Emmerich am Rhein Germany
  • OSRAM GmbH, Marcel-Breuer-Str. 4 80807 München Germany
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SCMG Europe GmbH, Amselweg 3 38667 Bad Harzburg Germany
  • SHELL CATALYSTS & TECHNOLOGIES BELGIUM, Pantserschipstraat 331 9000 Gent Belgium
  • Sinopec Europa GmbH, Messe Turm Friedrich-Ebert-Anlage 49 60308 Frankfurt am Main Germany
  • TANIOBIS GmbH, lm Schleeke 78-91 38642 Goslar Germany
  • TANIOBIS Smelting GmbH & Co. KG, Im Schleeke 78 -91 38642 Goslar Germany
  • Thermox Performance Materials GmbH, Bredeneyer Strasse 2b D-45133 Essen Germany
  • TODINI BV, Kleine Pathoekeweg 82 B-8000 Brugge Belgium
  • Traxys Europe SA, 19-21 Route Arlon same L-8009 Strassen Luxembourg Luxembourg
  • Treibacher Industrie AG, Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria
  • TSGE_2019-008, Im Fliegerhorst 12 38642 Goslar Germany
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • Umicore Specialty Powders France, 54 Avenue RHIN et DANUBE 38000 GRENOBLE France
  • UOP S.r.l._OR001, Viale Milanofiori Strada 1 - Palazzo E1 I-20090 Assago Milan Italy
  • Venator Uerdingen GmbH, Rheinuferstraße 7–9 47829 Krefeld Germany
  • Wolfram Bergbau und Hütten AG, Bergla 33 8543 St. Martin i. S. Austria
  • BASF Catalysts Germany GmbH, Seligmannallee 1 30173  Hannover Germany
  • BASF Nederland B.V., Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands
  • Seco Tools AB, Björnbacksvägen 2 SE-73782 FAGERSTA Sweden
  • Wogen Resources Europe Limited, The Black Church St Mary's Place D07 P4AX Dublin Ireland

Substance names and other identifiers

Tungsten
Other
Tungsten trioxide
EC Inventory
tungsten trioxide
REACH pre-registration
Trioxotungsten
C&L Inventory, Registration dossier, Other
tungsten
Other
Tungsten (VI) Oxide
C&L Inventory
Tungsten Oxide
C&L Inventory
Tungsten trioxid
Registration dossier
Tungsten Trioxide
C&L Inventory, Registration dossier
Tungsten Trioxide
C&L Inventory, Registration dossier
Tungsten Trioxide, Tungsten Yellow Oxide
Registration dossier
Tungsten Trioxide, Tungsten Yellow Oxide, Yellow Tungsten Oxide
Registration dossier
Tungsten Trioxide, yellow Tungsten Oxide, Tungsten Yellow Oxide
Registration dossier
tungsten troxide
C&L Inventory
Tungsten(VI) Oxide (99.9%, trace metals basis)
C&L Inventory
Wolframtrioxid
C&L Inventory
The substance is placed on the market as a part of the chemical matrix of an inorganic catalyst (i.e. regarded as a mixture according to: Guidance for Identification and Naming of Substance under REACH and CLP, Feb 2014. Therefore trade name for the substance does not exist.
Registration dossier
Tungsten Oxide Powder
C&L Inventory
TUNGSTEN TRIOXIDE
Registration dossier
Tungsten Yellow Oxide
Registration dossier
TYO
Registration dossier
Yellow Tungsten Oxide
Registration dossier
YTO
Registration dossier
1314-35-8
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration
37374-90-6
CAS number
Other
7440-33-7
CAS number
C&L Inventory, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Powder (100%) [2]
C Substance type
Inorganic (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 3 studies processed
R Melting / freezing point
1 472 - 1 473 °C @ 101.3 kPa [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
1 472 °C

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
1 837 °C @ 100 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
1 837 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
7.16 - 7.3 @ 20 - 23 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
7.3

Vapour pressure

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
84 mg/L @ 21 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
0.29 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
0.345

Adsorption/desorption

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 338 µg/L (1)
Intermittent releases (freshwater) 310 µg/L (1)
Marine water 33.8 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 79 mg/L (1)
Sediment (freshwater) 960 mg/kg sediment dw (1)
Sediment (marine water) 96 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 2.17 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 181 - 200 mg/L [2]
LC0 (4 days) 4.16 - 5.25 mg/L [2]
LC0 (72 h) 4.18 - 5.26 mg/L [2]
LC0 (48 h) 4.16 - 5.25 mg/L [2]
NOEC (4 days) 181 - 200 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (38 days) 9.8 - 10 mg/L [2]
LOEC (38 days) 10 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 163 mg/L [1]
EC50 (24 h) 163 mg/L [1]
EC0 (48 h) 2.6 mg/L [1]
EC0 (24 h) 5 mg/L [1]
NOEC (48 h) 90.8 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 44.2 - 100 mg/L [6]
LOEC (21 days) 85.1 - 100 mg/L [6]
EC50 (21 days) 78.7 - 100 mg/L [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
EC50 (72 h) 7.35 - 54.1 mg/L [4]
NOEC (72 h) 812 - 10 900 µg/L [3]
EC10 (72 h) 950 - 10 900 µg/L [3]
EC20 (72 h) 2.02 - 13.8 mg/L [3]
EC0 (72 h) 1 mg/L [1]

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
31 mg/L
EC10 or NOEC for freshwater algae
3.38 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (3 h) 10 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
10 g/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (56 days) 1 g/kg soil dw [1]
NOEC (28 days) 1 g/kg soil dw [1]
LOEC (56 days) 1 g/kg soil dw [1]
LOEC (28 days) 1 g/kg soil dw [1]
EC10 (56 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
586 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
NOEC (21 days) 37 - 1 000 mg/kg soil dw [3]
EC50 (21 days) 534 - 1 000 mg/kg soil dw [4]
EC25 (21 days) 93.9 - 1 000 mg/kg soil dw [7]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
22 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (28 days) 1 g/kg soil dw [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50
586 mg/kg soil dw

Toxicity to birds

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
45 mg/kg food

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.36 mg/L air (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Inhalation route:
Adverse effect observed LC50 5.36 mg/L air
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 4 studies processed
P/RResults
NOAEL (rat): 75 - 200 mg/kg bw/day [3]
NOAEL (rat): 500 mg/L drinking water [1]
NOAEL (mouse): 500 mg/L drinking water [1]
LOAEL (rat): 125 - 200 mg/kg bw/day [6]
LOAEL (rat): 1 000 mg/L drinking water [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (rat): 652 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed BMDL10 102 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 650 mg/m³ (subchronic, rat)
Inhalation route - local effects:
No adverse effect observed NOAEC 650 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 3
Supporting study 1 5
Weight of evidence 1
Other 2
Data waiving
no waivers
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 160 mg/kg bw/day (subchronic, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 100 mg/kg bw/day (subchronic, rabbit)

Neurotoxicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 125 mg/kg bw/day (subchronic, rat)

Immunotoxicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 132.11 mg/kg bw/day (subchronic, mouse)

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant