Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

No image available
EC / List no.:
213-934-0
CAS no.:
1067-53-4
Index number:
014-050-00-6
Molecular formula:
SMILES:
InChI:
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
6
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP15) approved by the European Union, this substance may damage fertility and may damage the unborn child.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may damage fertility or the unborn child and may cause damage to organs through prolonged or repeated exposure.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is suspected of damaging fertility or the unborn child, is harmful in contact with skin, causes serious eye irritation, is harmful if swallowed and is harmful if inhaled.

Breakdown of all 243 C&L notifications submitted to ECHA

Repr. 2 H361
Acute Tox. 4 H312
Eye Irrit. 2 H319
Repr. 1B H360FD Harmonised Classification
Acute Tox. 4 H302
Acute Tox. 4 H332
STOT RE 2 H373
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L, Candidate list of SVHCs).
  • R
There is broad agreement in that a majority of data submitters agree this substance is Toxic to Reproduction (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 4 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Substance of very high concern (SVHC) and included in the candidate list for authorisation.
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: adhesives and sealants and polymers.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and building & construction work. This substance is used for the manufacture of: textile, leather or fur, wood and wood products, pulp, paper and paper products, rubber products, plastic products, fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, industrial spraying, transfer of substance into small containers, roller or brushing applications, treatment of articles by dipping and pouring, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, hand mixing with intimate contact only with personal protective equipment available and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

This substance is used in the following products: polymers, non-metal-surface treatment products and adhesives and sealants.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and transfer of chemicals.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: polymers, non-metal-surface treatment products, adhesives and sealants and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals, rubber products and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, mixing in open batch processes and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in the production of articles, for thermoplastic manufacture, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, transfer of chemicals, closed processes with no likelihood of exposure, transfer of substance into small containers and manual maintenance (cleaning and repair) of machinery.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; use personal protective equipment as required.; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Get medical advice/attention if you feel unwell. If exposed or concerned: get medical advice/attention.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • Momentive Performance Materials GmbH, Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany
  • Momentive Performance Materials Specialties Srl, Zona Industriale- Località Rivolta Del Re Termoli 86039 Termoli CB Italy
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany

Substance names and other identifiers

Tris(2-methoxyethoxy) vinylsilane
Cosmetic Products Regulation, Annex II - Prohibited Substances
tris(2-methoxyethoxy) vinylsilane; 6-(2-methoxyethoxy)- 6-vinyl-2,5,7,10-tetraoxa-6-silaundecane
C&L Inventory
Tris(2-methoxyethoxy)vinylsilane
EC Inventory, Candidate list, REACH pre-registration
Tris(2-methoxyethoxy)vinylsilane
Candidate list, REACH pre-registration, Other
tris(2-methoxyethoxy)vinylsilane; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
tris(2-methoxyethoxy)vinylsilaan; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaündecaan; (nl)
C&L Inventory
tris(2-methoxyethoxy)vinylsilan; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecan (da)
C&L Inventory
Tris(2-methoxyethoxy)vinylsilan; 6-(2-Methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecan (de)
C&L Inventory
tris(2-methoxyethoxy)vinylsilan; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundekan (cs)
C&L Inventory
tris(2-metoksietoksi)vinilsilan; 6-(2-metoksietoksi)-6-vinil-2,5,7,10-tetraoksa-6-silaundekan (hr)
C&L Inventory
tris(2-metoksietoksi)vinilsilan; 6-(2-metoksietoksi)-6-vinil-2,5,7,10-tetraoksa-6-silaundekan (sl)
C&L Inventory
tris(2-metoksietoksi)vinilsilanas; 6-(2-metoksietoksi)-6-vinil-2,5,7,10-tetraoksa-6-silaundekanas (lt)
C&L Inventory
tris(2-metoksietoksi)vinilsilāns; 6-(2-metoksietoksi)-6-vinil-2,5,7,10-tetraoksa-6-silaundekāns (lv)
C&L Inventory
tris(2-metoksietoksi)vinyylisilaani; 6-(2-metoksietoksi)-6-vinyyli-2,5,7,10-tetraoksa-6-silaunidekaani (fi)
C&L Inventory
tris(2-metoksyetoksy)winylosilan; 6-(2-metoksyetoksy)-6-winylo-2,5,7,10-tetraoksa-6-silaundekan (pl)
C&L Inventory
Tris(2-metoksüetoksü)vinüülsilaan; 6-(2-metoksüetoksü)-6-vinüül-2,5,7,10-tetraoksa-6-silaundekaan (et)
C&L Inventory
tris(2-metossietossi)vinilsilan; 6-(2-metossietossi)-6-vinil-2,5,7,10-tetraoksa-6-silaundekan (mt)
C&L Inventory
tris(2-metossietossi)vinilsilano; 6-(2-metossietossi)-6-vinil-2,5,7,10-tetraossa-6-silaundecano (it)
C&L Inventory
tris(2-metoxietoxi)vinilsilan; 6-(2-metoxietoxi)-6-vinil-2,5,7,10-tetraoxa-6-silaundecan (ro)
C&L Inventory
Tris(2-metoxietoxi)vinilsilano; 6-(2-metoxietoxi)-6-vinil-2,5,7,10-tetraoxa-6-silaundecano (es)
C&L Inventory
tris(2-metoxietoxi)vinilsilano; 6-(2-metoxietoxi)-6-vinil-2,5,7,10-tetraoxa-6-silaundecano (pt)
C&L Inventory
tris(2-metoxietoxi)vinylsilan; 6-(2-metoxetoxi)-6-vinyl-2,5,7,10-tetraoxa-6-silaundekan (sv)
C&L Inventory
tris(2-metoxyetoxy)vinylsilán; 6-(2-metoxyetoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundekán (sk)
C&L Inventory
tris(2-méthoxyéthoxy)vinylsilane; 6-(2-méthoxyéthoxy)-6-vinyl-2,5,7,10-tétraoxa-6-silaundécane (fr)
C&L Inventory
trisz(2-metoxietoxi)vinilszilán; 6-(2-metoxietoxi)-6-vinil-2,5,7,10-tetraoxa-6-szilaundekán (hu)
C&L Inventory
τρις(2-μεθοξυαιθοζυ)βινυλοσιλάνιο· 6-(2-μεθοξυαιθοξυ)-6-βινυλο-2,5,7,10-τετραοξα-6-σιλαενδεκάνιο (el)
C&L Inventory
винилтрис(2-метоксиетокси)силан; 6-винил-6-(2-метоксиетокси)-2,5,7,10-тетраокса-6-силаундекан (bg)
C&L Inventory
2,5,7,10-Tetraoxa-6-silaundecane, 6-ethenyl-6-(2-methoxyethoxy)-
Candidate list
2,5,7,10-Tetraoxa-6-silaundecane, 6-ethenyl-6-(2-methoxyethoxy)-
C&L Inventory
6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane
C&L Inventory, Registration dossier
6-(2-methoxyethoxy)-7-silyl-2,5,8,11-tetraoxadodec-6-ene
C&L Inventory
[tris(2-methoxyethoxy)ethenyl]silane
C&L Inventory
Ethenyl-tris(2-methoxyethoxy)silane
C&L Inventory, Registration dossier, Other
methoxyethoxyvinylsilane
Registration dossier
tris(2-methoxyethoxy) vinylsilane
C&L Inventory
TRIS(2-METHOXYETHOXY)VINYLSILANE
C&L Inventory
Tris(2-methoxyethoxy)vinylsilane
C&L Inventory, Registration dossier
Vinyl tris(2-methoxyethoxy)silane
C&L Inventory
Vinyltris(2-methoxyethoxy)silane
C&L Inventory
Vinyltris(methoxyethoxy)silane
C&L Inventory
Dynasylan(R) VTMO
Registration dossier
SILQUEST A-172 SILANE
Registration dossier
Silquest A-172NT -J silane
Registration dossier
014-050-00-6
Index number
C&L Inventory
1067-53-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
1108196-61-7
CAS number
Other
1637457-78-3
CAS number
Other
59250-02-1
CAS number
Other
609347-89-9
CAS number
Other
947734-83-0
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Liquid (100%) [1]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 8 studies submitted
  • 2 studies processed
R Melting / freezing point
-130 °C @ 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 3 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
-130 - -85.1 °C

Boiling point

Study results
  • 15 studies submitted
  • 2 studies processed
R Boiling point
277.85 - 285 °C @ 101.3 kPa [3]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 6 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
280 °C

Density

Study results
  • 9 studies submitted
  • 2 studies processed
R Density
1.02 g/cm³ @ 20 °C [1]
R Relative density
1.03 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 3 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 10 studies submitted
  • 2 studies processed
R Vapour pressure
0.434 Pa @ 25 °C [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 3 2
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
0.017 - 1 300 Pa @ 25 °C

Partition coefficient

Study results
  • 7 studies submitted
  • 2 studies processed
R Log Pow
0.26 - 0.3 @ 20 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1 2 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Log Kow (Log Pow)
-2 - 0.3 @ 20 °C

Water solubility

Study results
  • 9 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
71.479 g/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 3 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Water solubility
220 - 1 000 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 15 studies submitted
  • 2 studies processed
R Flash point
115 - 133 °C @ 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 5 4
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
133 °C

Auto flammability

Study results
  • 4 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
213 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
213 °C

Flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 1 summary processed
pKa at 20 °C
10

Viscosity

Study results
  • 4 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
2.3 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
2.8 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Half life in air
4.8 - 31.2 h
Degradation rate constant with OH radicals
0 - 0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life for hydrolysis
61.5 min @ 25 °C

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 2 studies processed
C Interpretation of results
Readily biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Biodegradation in water
Readily biodegradable (67%), Under test conditions no biodegradation observed (33%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
R Summaries
  • 3 summaries submitted
  • 2 summaries processed
Koc at 20°C
1 - 9.6

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Henry's law constant
0 - 0.099 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 3 summaries submitted
  • 3 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 400 µg/L (1)
Intermittent releases (freshwater) 1.19 mg/L (1)
Marine water 40 µg/L (1)
Intermittent releases (marine water) No hazard identified (2)
Sewage treatment plant (STP) No hazard identified (3)
Sediment (freshwater) 1.5 - 38 mg/kg sediment dw (2)
Sediment (marine water) 150 - 3 800 µg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (3)
Hazard for Terrestrial Organism
Soil 11 - 2 040 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (3)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 100 mg/L [2]
NOEC (4 days) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 314 - 314.1 mg/L [2]
EC50 (24 h) 612 - 612.4 mg/L [2]
EC100 (48 h) 996 - 996.3 mg/L [2]
NOEC (48 h) 110.7 - 111 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 28.1 - 500 mg/L [2]
LOEC (21 days) 52.4 mg/L [1]
EC50 (21 days) 119 mg/L [1]

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (72 h) 304 - 611 mg/L [4]
NOEC (72 h) 75 mg/L [2]
EC10 (72 days) 136 mg/L [1]
EC10 (72 h) 79 - 136 mg/L [3]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
231 mg/L
EC10 or NOEC for freshwater algae
28 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 590 µg/m³ effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 80 µg/kg bw/day effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 100 µg/m³ effect on fertility
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 40 µg/kg bw/day effect on fertility
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 7 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Category 5 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
dermal
  • 4 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 2 000 mg/kg bw
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 25 - 75 mg/kg bw/day [4]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 10 ppm [1]
LOAEC (rat): 100 ppm [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 25 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No study available

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
Adverse effect observed NOAEL 25 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 75 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant