Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-444-5
CAS no.:
106-93-4
Index number:
602-010-00-6
Molecular formula:
C2H4Br2
SMILES:
BrCCBr
InChI:
InChI=1S/C2H4Br2/c3-1-2-4/h1-2H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
7
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed, is toxic in contact with skin, is toxic if inhaled, may cause cancer, is toxic to aquatic life with long lasting effects, causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Breakdown of all 120 C&L notifications submitted to ECHA

Acute Tox. 3 H301 Harmonised Classification
Acute Tox. 3 H311 Harmonised Classification
Aquatic Chronic 2 H411 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Acute Tox. 2 H330
Carc. 2 H351
Carc. 1A H350
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • PBT
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Persistent, Bioaccumulative and Toxic (14.29% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 7 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
This substance is subject to the Prior Informed Consent regulation and to export notification procedure from 07-Mar-2003
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

This substance is used in articles, in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation and mixing in open batch processes.

Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: fuels, pH regulators and water treatment products, laboratory chemicals, pharmaceuticals, photo-chemicals and polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, in materials as fuel sources, with limited exposure to unburned product to be expected, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: fuels, laboratory chemicals, pharmaceuticals, pH regulators and water treatment products, photo-chemicals and polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of chemicals, closed batch processing in synthesis or formulation and in materials as fuel sources, with limited exposure to unburned product to be expected.

Release to the environment of this substance can occur from industrial use: of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, in processing aids at industrial sites and as processing aid. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, as processing aid and of substances in closed systems with minimal release. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Aceto France SAS, 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France
  • CS Regulatory Ireland Ltd. in its legal capacity as OR for LANXESS Solutions UK Ltd, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • ICL Europe Coöperatief U.A. (OR1), Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands
  • Innospec Performance Chemicals France SAS (Only Rep 2), Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France
  • TotalEnergies Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • Vynova PPC SAS, 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France
  • Warter Fuels Spółka Akcyjna, Koralowa 60 02-967 Warszawa Poland

Substance names and other identifiers

1,2-Dibrom-ethan
1,2-Dibromethan
1,2-dibromoethane
EC Inventory, C&L Inventory, REACH pre-registration, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work,
1,2-Dibromoethane
C&L Inventory, REACH pre-registration, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work,
1,2-dibromoethane (EDB)
PIC, Other, PIC Annex I, PIC Import notification,
ETHYLENE DIBROMIDE
Other, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, CMD - Carcinogens and Mutagens Directive, Annex III - OELVs
Ethylene Dibromide (EDB)
1,2-dibrometan (ro)
C&L Inventory
1,2-dibrometan 1,2-etylendibromid (no)
C&L Inventory
1,2-dibrometan 1,2-etylendibromid (sv)
C&L Inventory
1,2-dibrometanas (lt)
C&L Inventory
1,2-dibromethan (cs)
C&L Inventory
1,2-dibromethan (da)
C&L Inventory
1,2-Dibromethan Ethylendibromid (de)
C&L Inventory
1,2-dibrometāns (lv)
C&L Inventory
1,2-dibromoetaan (et)
C&L Inventory
1,2-dibromoetan (hr)
C&L Inventory
1,2-dibromoetan (sl)
C&L Inventory
1,2-dibromoetan dibromek etylenu bromek etylenu (pl)
C&L Inventory
1,2-dibromoetano (es)
C&L Inventory
1,2-dibromoetano (it)
C&L Inventory
1,2-dibromoetano (pt)
C&L Inventory
1,2-dibromoéthane (fr)
C&L Inventory
1,2-dibroomethaan (nl)
C&L Inventory
1,2-dibrómetán (hu)
C&L Inventory
1,2-dibrómetán (sk)
C&L Inventory
1,2-etyleenidibromidi (fi)
C&L Inventory
1,2-διβρωμοαιθάνιο (el)
C&L Inventory
1,2-дибромоетан (bg)
C&L Inventory
1,2-Dibromethan
C&L Inventory
1,2-DIBROMOETHANE
C&L Inventory, Registration dossier, Other
1,2-dibromoethane
C&L Inventory, Registration dossier, Other
Dibromoethane
C&L Inventory
Ethylene dibromide
Registration dossier
106-93-4
CAS number
EC Inventory, C&L Inventory, PIC, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, CMD - Carcinogens and Mutagens Directive, Annex III - OELVs, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work, PIC Annex I, PIC Import notification,
2903 62 00
CN Code
PIC, Other
2903 62 00
CN number
PIC
2903.62
HS Code
PIC, Other, PIC Annex I
3808.59
HS Code Mixture
PIC, Other, PIC Annex I
56729-21-6
CAS number
Other
602-010-00-6
Index number
C&L Inventory
625084-37-9
CAS number
Other
8003-07-4
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant