Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-441-9
CAS no.:
106-91-2
Index number:
607-123-00-4
Molecular formula:
C7H10O3
SMILES:
CC(=C)C(=O)OCC1CO1
InChI:
InChI=1/C7H10O3/c1-5(2)7(8)10-4-6-3-9-6/h6H,1,3-4H2,2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
17
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in CLP notifications this substance is toxic in contact with skin, causes damage to organs, may cause cancer, may damage fertility or the unborn child, causes severe skin burns and eye damage, is harmful if swallowed, causes serious eye damage, is harmful if inhaled, is suspected of causing genetic defects, may cause an allergic skin reaction, causes skin irritation and may cause respiratory irritation.

Breakdown of all 1142 C&L notifications submitted to ECHA

Acute Tox. 4 H302
Skin Sens. 1 H317
Acute Tox. 4 H332
Eye Irrit. 2 H319
Skin Irrit. 2 H315
Acute Tox. 3 H311
Acute Tox. 4 H312
Carc. 1B H350
Muta. 2 H341
Repr. 1B H360
STOT SE 1 H370
Eye Dam. 1 H318
Skin Corr. 1C H314
STOT RE 1 H372
STOT SE 3 H335
https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (27.15% of CLP notifications).
  • R
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Toxic to Reproduction (27.15% of CLP notifications).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (99.91% of CLP notifications).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 29 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation, the low energy manipulation of substances bound in materials or articles, transfer of chemicals at dedicated facilities and heat / pressure transfer fluids in closed systems.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: pH regulators and water treatment products and laboratory chemicals.

This substance is used in the following areas: health services and scientific research and development.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: polymers and coating products.

This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and in the production of articles.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of chemicals at dedicated facilities, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; use only outdoors or in a well-ventilated area; obtain special instructions before use; do not eat, drink or smoke when using this product; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: Wash contaminated clothing before reuse. Call a poison center or doctor/physician if you feel unwell. Follow specific measures (see label). If skin irritation or a rash occurs: get medical advice/attention. If exposed or concerned: get medical advice/attention. Get medical advice/attention if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Immediately call a poison center or doctor/physician. If swallowed: call a poison center or doctor/physician if you feel unwell.

Storage statements

Store this substance locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • Alpha OR MCC CTM Japan, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • B.I.G. - OR634, Technische Schoolstraat 43A 2440 Geel Belgium
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas Rd D12XV7K Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Shandong GP Natural Products Co., Ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Zaozhuang Weicheng Chemical Technology Co., Ltd), Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CS Regulatory IRL Ltd 1L-10, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • DKSH Italia S.r.l., Via Salvatore Rosa, 14 20156 Milano Italy
  • DOW BENELUX B.V. - OR1, Postbus 48 4530 AA Terneuzen Netherlands
  • ECEM, Hogehilweg 18 1101CD Amsterdam Noord Holland Netherlands
  • Huntsman Advanced Materials (Europe) BV OR-USA, Everslaan 45 B-3078 Everberg Belgium
  • Jindal Films Europe Virton srl, Zoning Industriel de Latour 6761 VIRTON Belgium
  • Knoell NL-OR-047, Agro Business Park 75 6708PV Wageningen Netherlands
  • LORD Germany GMBH, Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany
  • Novasol S.A., Mechelsesteenweg 455 1950 Kraainem Belgium
  • Pioneer Solutions Europe BVBA, De Roskam 13 2970 Schilde Belgium
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • Stadex Nederland BV as OR for Jiangxi, Boxbergerweg 119 7431PM Diepenveen Netherlands
  • Stadex Nederland BV as OR for Jin Dun, Boxbergerweg 119 7431PM Diepenveen Netherlands
  • Synthomer Trading Limited Dutch Branch, Ijsselstraat 41 5347 KG Oss Netherlands
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • [Confidential], [Confidential]
  • NetSun EU B.V., Blaak 40, Floor 5 3011 TA Rotterdam Netherlands
  • Stadex Nederland BV, Boxbergerweg 119 7431PM Diepenveen Netherlands

Substance names and other identifiers

1-Propanol, 2,3-epoxy-, methacrylate
Other
2,3-epoxypropyl methacrylate
EC Inventory, C&L Inventory, REACH pre-registration, Other, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
2,3-Epoxypropyl methacrylate
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
2,3-epoxypropyl methacrylate; glycidyl methacrylate
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
2,3-Epoxypropyl methacrylic acid ester
Other
2-((Methacryloxy)methyl)oxirane
Other
2-Propenoic acid, 2-methyl-, 2-oxiranylmethyl ester
Other
2-Propenoic acid, 2-methyl-, oxiranylmethyl ester
Other
Acriester G
Other
Blemmer G
Other
Blemmer GMA
Other
Glycidol methacrylate
Other
Glycidyl alpha-methyl acrylate
Other
Glycidyl methacrylate
C&L Inventory, Other, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Light Ester G
Other
Methacrylic acid, 2,3-epoxypropyl ester
Other, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
SR 379
Other
(oxiranylmetyl)-metakrylát (sk)
C&L Inventory
2,3-epoksipropil metakrilat (sl)
C&L Inventory
2,3-epoksipropil-metakrilat (hr)
C&L Inventory
2,3-epoksipropilmetakrilatas (lt)
C&L Inventory
2,3-epoksipropilmetakrilāts (lv)
C&L Inventory
2,3-epoksypropylmetakrylat (no)
C&L Inventory
2,3-epoksüpropüülmetakrülaat (et)
C&L Inventory
2,3-epossipropile metacrilato (it)
C&L Inventory
2,3-epoxipropil metacrilat (ro)
C&L Inventory
2,3-epoxipropil-metakrilát (hu)
C&L Inventory
2,3-epoxipropylmetakrylat (sv)
C&L Inventory
2,3-epoxypropyl-methakrylát (cs)
C&L Inventory
2,3-epoxypropylmethacrylaat (nl)
C&L Inventory
2,3-epoxypropylmethacrylat (da)
C&L Inventory
2,3-Epoxypropylmethacrylat (de)
C&L Inventory
2,3-епоксипропил метакрилат (bg)
C&L Inventory
ester 2,3-epoksypropylowy kwasu metakrylowego (pl)
C&L Inventory
glicidil metacrilat (ro)
C&L Inventory
glicidil metacrilato (it)
C&L Inventory
glicidil metakrilat (sl)
C&L Inventory
glicidil-metakrilat (hr)
C&L Inventory
glicidil-metakrilát (hu)
C&L Inventory
glicidilmetakrilatas (lt)
C&L Inventory
glicidilmetakrilāts (lv)
C&L Inventory
glycidyl-metakrylát (sk)
C&L Inventory
glycidyl-methakrylát (cs)
C&L Inventory
glycidylmetakrylat (no)
C&L Inventory
glycidylmetakrylat (sv)
C&L Inventory
glycidylmethacrylaat (nl)
C&L Inventory
glycidylmethacrylat (da)
C&L Inventory
Glycidylmethacrylat (de)
C&L Inventory
Glysidyylimetakrylaatti (fi)
C&L Inventory
Glütsidüülmetakrülaat (et)
C&L Inventory
metacrilato de 2,3-epoxipropilo (es)
C&L Inventory
metacrilato de 2,3-epoxipropilo (pt)
C&L Inventory
metacrilato de glicidilo (es)
C&L Inventory
metacrilato de glicidilo (pt)
C&L Inventory
metakrylan 2,3-epoksypropylu (pl)
C&L Inventory
metakrylan glicydowy (pl)
C&L Inventory
méthacrylate de 2,3-époxypropyle (fr)
C&L Inventory
méthacrylate de glycidyle (fr)
C&L Inventory
μεθακρυλικός 2,3-εποξυπροπυλεστέρας μεθακρυλικός γλυκυδυλεστέρας (el)
C&L Inventory
глицидил метакрилат (bg)
C&L Inventory
2-Propenoic acid, 2-methyl-, 2-oxiranylmethyl ester
Other
(2,3-Epoxy-propyl)-methacrylat
C&L Inventory
(2S)-oxiran-2-yl]methyl 2-methylprop-2-enoate
C&L Inventory
(oxiran-2-yl)methyl 2-methylprop-2-enoate
Registration dossier, Other
2,3-Epoxypropyl methacrylate
C&L Inventory, Registration dossier
2,3-epoxypropyl methacrylate
C&L Inventory, Registration dossier
2,3-epoxypropyl methacrylate/glycidyl methacrylate
C&L Inventory
2,3-epoxypropyl methacrylate/glycidyl methacrylate
Registration dossier
2,3-epoxypropyl methacrylate; glycidyl methacrylate
C&L Inventory
2,3-Epoxypropylmethacrylat
C&L Inventory
2-Oxiranylmethyl 2-methylacrylate, Glycidyl methacrylate
Registration dossier
2-propenoic acid, 2-methyl-,2-oxiranylmethyl ester
C&L Inventory
GLYCIDYL METHACRYLATE
C&L Inventory, Registration dossier
Glycidyl Methacrylate
C&L Inventory, Registration dossier
Glycidyl Methacrylate (stabilized with MEHQ)
C&L Inventory
glycidylmethacrylate
Registration dossier
GMA
Registration dossier
Methacrylsäure-2,3-epoxypropylester
C&L Inventory
oxiran-2-yl methyl 2-methylprop-2-enoate
C&L Inventory
oxiran-2-ylmethyl 2-methylprop-2-enoate
C&L Inventory, Registration dossier, Other
oxiran-2-ylmethyl methacrylate
C&L Inventory, Registration dossier
2,3-epoxypropyl methacrylate
Registration dossier
ACRYESTER G
Registration dossier
Glycidyl methacrylate
C&L Inventory, Registration dossier
Glycidyl methacrylate; stab. with 100ppm 4-methoxyphenol
C&L Inventory
GMA
Registration dossier
106-91-2
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
117955-24-5
CAS number
Other
117955-24-5
Deleted CAS number
Other
122785-80-2
CAS number
Other
122785-80-2
Deleted CAS number
Other
126872-19-3
CAS number
Other
126872-19-3
Deleted CAS number
Other
1451188-70-7
CAS number
Other
1451188-70-7
Deleted CAS number
Other
169957-95-3
CAS number
Other
169957-95-3
Deleted CAS number
Other
201732-55-0
CAS number
Other
201732-55-0
Deleted CAS number
Other
202149-12-0
CAS number
Other
202149-12-0
Deleted CAS number
Other
203300-26-9
CAS number
Other
203300-26-9
Deleted CAS number
Other
210093-72-4
CAS number
Other
210093-72-4
Deleted CAS number
Other
55279-88-4
CAS number
Other
55279-88-4
Deleted CAS number
Other
607-123-00-4
Index number
C&L Inventory
865699-83-8
CAS number
Other
865699-83-8
Deleted CAS number
Other
89678-75-1
CAS number
Other
89678-75-1
Deleted CAS number
Other
96778-02-8
CAS number
Other
96778-02-8
Deleted CAS number
Other
98104-93-9
CAS number
Other
98104-93-9
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-41.5 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-41.5 °C

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
189 - 197.9 °C @ 1.018 - 1 013.25 hPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
189 °C

Density

Study results
  • 1 study submitted
  • 1 study processed
R Density
0.001 g/cm³ @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.07

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
4.2 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
4.2 hPa @ 25 °C

Partition coefficient

Study results
  • 1 study submitted
  • 1 study processed
R Log Pow
0.96 @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
0.96 @ 25 °C

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
50 g/L @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
50 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
25 mN/m

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
76 - 84 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
76 °C

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
389 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
389 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R Other:
5.481 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
5.481 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life for hydrolysis
87.84 h @ 25 °C

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable but failing the 10-day window (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable but failing the 10-day window (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 10 µg/L (1)
Intermittent releases (freshwater) 100 µg/L (1)
Marine water 1 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 90 µg/kg sediment dw (1)
Sediment (marine water) 9 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 90 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 days) 2.8 mg/L [1]
LC50 (72 h) 3.7 mg/L [1]
LC50 (48 h) 5.7 mg/L [1]
LC50 (24 h) 12.9 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (14 days) 1.2 mg/L [1]
LC50 (14 days) 1.9 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 24.9 mg/L [1]
EC50 (24 h) 42.3 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 1.02 mg/L [1]
LOEC (21 days) 3.18 mg/L [1]
EC50 (21 days) 3.18 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (72 h) 9.2 - 14.6 mg/L [2]
NOEC (72 h) 2.4 - 3.2 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
14.6 mg/L
EC10 or NOEC for freshwater algae
3.2 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 45 µg/m³ carcinogenicity
Acute /short term: (No hazard identified) -
Local Effects
Long-term: (DNEL) 240 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 720 µg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 12.76 µg/kg bw/day carcinogenicity
Acute /short term: (High hazard (no threshold derived)) -
Local Effects
Long-term: (DNEL) 2.24 µg/cm² repeated dose toxicity
Acute /short term: (DNEL) 6.72 µg/cm² repeated dose toxicity
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 4 µg/m³ carcinogenicity
Acute /short term: (Low hazard (no threshold derived)) -
Local Effects
Long-term: (DNEL) 60 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 180 µg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 2.3 µg/kg bw/day carcinogenicity
Acute /short term: (High hazard (no threshold derived)) -
Local Effects
Long-term: (DNEL) 1.12 µg/cm² repeated dose toxicity
Acute /short term: (DNEL) 3.36 µg/cm² repeated dose toxicity
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 2.3 µg/kg bw/day carcinogenicity
Acute /short term: (High hazard (no threshold derived)) -
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 6 studies submitted
  • 1 study processed
P/RResults
LD50 597 mg/kg bw (rat) [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 6 studies submitted
  • 1 study processed
P/RResults
LC0 (4 h) 412 ppm (rat) [1]

inhalation
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 480 mg/kg bw (rabbit) [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 4 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 10 - 30 mg/kg bw/day [3]
LOAEL (rat): 30 - 100 mg/kg bw/day [3]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Study data: inhalation
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 12 mg/m³ air [1]
LOAEL (rat): 58.2 - 87 mg/m³ air [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 30 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
Adverse effect observed NOAEC 12 mg/m³ (subchronic, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 12 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed T25 57 mg/kg bw/day (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant