Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
200-751-6
CAS no.:
71-36-3
Index number:
Molecular formula:
C4H10O
SMILES:
CCCCO
InChI:
InChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
5
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a flammable liquid and vapour, is harmful if swallowed, causes serious eye damage, causes skin irritation, may cause respiratory irritation and may cause drowsiness or dizziness.

Breakdown of all 6651 C&L notifications submitted to ECHA

Flam. Liq. 3 H226 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
Eye Dam. 1 H318 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
STOT SE 3 H336 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Acute Tox. 4 H332
STOT RE 1 H372
Acute Tox. 2 H302
Eye Irrit. 2 H319
Not Classified
Asp. Tox. 1 H304
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 4 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: lubricants and greases, adhesives and sealants, anti-freeze products, coating products, fillers, putties, plasters, modelling clay, polishes and waxes and washing & cleaning products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: coating products and fillers, putties, plasters, modelling clay.

This substance is used in the following areas: mining, agriculture, forestry and fishing, printing and recorded media reproduction, building & construction work, health services and scientific research and development.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, non-industrial spraying, treatment of articles by dipping and pouring and batch processing in synthesis or formulation with opportunity for exposure.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, laboratory work, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and manufacturing of the substance.

This substance is used in the following products: coating products and fillers, putties, plasters, modelling clay.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and roller or brushing applications.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • DEZA a.s., Masarykova 753 75701 Valasske Mezirici Czech Republic
  • Huntsman Advanced Materials (Europe) BV, Everslaan 45 B-3078 Everberg Belgium
  • Kerona Scientific Ltd, 14 Thomas Hand Street K34 A375 Skerries Dublin Ireland
  • Perstorp Oxo AB, Sanden Ödsmål 444 84 Stenungsund Sweden

Substance names and other identifiers

1-Butanol
Food Contact Regenerated Cellulose Directive - Authorised Substances, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
butan-1-ol; n-butanol
Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
Butyl alcohol
Other
1-бутанол (bg)
C&L Inventory
Alcohol butylowy (pl)
C&L Inventory
butaan-1-ol (nl)
C&L Inventory
butaan-1-ool (et)
C&L Inventory
butan-1-ol (cs)
C&L Inventory
butan-1-ol;n-butanol (fr)
C&L Inventory
Butan-1-oli (fi)
C&L Inventory
butan-1-olis (lt)
C&L Inventory
butan-1-olo (it)
C&L Inventory
butanol (sk)
C&L Inventory
bután-1-ol (hu)
C&L Inventory
butān-1-ols (lv)
C&L Inventory
n-butanol (cs)
C&L Inventory
n-butanoli (fi)
C&L Inventory
n-butanolis (lt)
C&L Inventory
n-butanolo (it)
C&L Inventory
n-butanols (lv)
C&L Inventory
n-butanool (et)
C&L Inventory
n-βουτανόλη (el)
C&L Inventory
n-бутанол (bg)
C&L Inventory
βουταν-1-όλη (el)
C&L Inventory
1-Butanol (n-Butanol)
Registration dossier
1-Hydroxy Butane
C&L Inventory
Buan-1-ol
Registration dossier
Butan-1-ol,
C&L Inventory
butan-1-ol/n-butanol
C&L Inventory
butan-1.ol
C&L Inventory
Butan-2-ol
C&L Inventory
EC 200-751-6 n-Butanol
Registration dossier
Isobutanol
Registration dossier
Isobutanol, n-Butyl Alcohol
Registration dossier
n-butano
C&L Inventory
n-Butyl Alcohol
C&L Inventory
NORMAL BUTYL ALCOHOL
C&L Inventory
Reaction mass of benzyl alcohol and xylene and m-phenylenebis(methylamine) and Quartz (SiO2) and Formaldehyde, oligomeric reaction products with phenol and m-phenylenebis(methylamine)
C&L Inventory
1-Butanol (9CI)
Registration dossier
1-butanolo
C&L Inventory
1-Butyl alcohol
Registration dossier
1-hydroxybutane
Registration dossier
A-UT6581(K1)PTA
Registration dossier
A/F7830-DARKBROWN
Registration dossier
A/F7830-REDBROWN
Registration dossier
A/F795-DARKBROWN
Registration dossier
A/F795-REDBROWN
Registration dossier
A/F7950-DARKBROWN
Registration dossier
A/F7950-REDBROWN
Registration dossier
Butyl alcohol (8CI)
Registration dossier
Butyl hydroxide
Registration dossier
Butylalcohol
Registration dossier
CCS 203
Registration dossier
Eastman™ n-Butanol
Registration dossier
EgisArrow-DARKBROWN
Registration dossier
EgisArrow-REDBROWN
Registration dossier
EgisPacific(L)-DARKBROWN
Registration dossier
EgisPacific(L)-REDBROWN
Registration dossier
EgisPacific(M)-DARKBROWN
Registration dossier
EgisPacific(M)-REDBROWN
Registration dossier
EgisPacific-DARKBROWN
Registration dossier
EgisPacific-REDBROWN
Registration dossier
EH2350PTA-1128
Registration dossier
EH2350PTA-1128(M)
Registration dossier
EH2350PTA-1135
Registration dossier
EH2350PTA-2260(M)
Registration dossier
EH2350PTA-RAL9002
Registration dossier
EH2350PTA-RAL9002(M)
Registration dossier
EH2350PTB(M)
Registration dossier
EH2590
Registration dossier
EH2590-A-1105
Registration dossier
EH6270-A-10GY6.5/3
Registration dossier
EH6270-A-1128
Registration dossier
EH6270-B
Registration dossier
EP1760-A-1135
Registration dossier
ET5740PTB
Registration dossier
Hemostyp
Registration dossier
Methylolpropane
Registration dossier
N300PTB
Registration dossier
Nacol 4
Registration dossier
nBUTANOL
C&L Inventory
PP100
Registration dossier
Propylcarbinol
Registration dossier
ST1020-A-RAL1014
Registration dossier
UP5403(KC)
Registration dossier
UT6581(K1)PTA-1000
Registration dossier
UT6581(K1)PTA-1999
Registration dossier
UT6581(K1)PTB
Registration dossier
UT6581-A-10GY6.5/3
Registration dossier
UT6581-A-N.1.5
Registration dossier
UT6581-A-RAL9006(H)
Registration dossier
UT6581-B
Registration dossier
107569-51-7
CAS number
Other
1154866-91-7
CAS number
Other
220713-25-7
CAS number
Other
42031-19-6
CAS number
Other
603-004-00-6
Index number
C&L Inventory
71-36-3
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Food Contact Regenerated Cellulose Directive - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant