Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 217-157-8 | CAS number: 1758-73-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96 h): > 100 mg/L for Oryzias latipes (OECD 203)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
Two experimental studies are available investigating the
short-term toxicity of aminoiminomethanesulphinic acid (CAS No.
1758-73-2) to fish. The key study was performed according to OECD 203
(GLP) with Oryzias latipes (MOE, 1999). A nominal concentration of 100
mg/L was tested under flow-through conditions in a limit test. Based on
HPLC measurements the concentrations were measured to be within 80% of
nominal. Therefore, the effect concentrations were based on the nominal
concentrations. An LC50 >100 mg/L (nominal) was determined.
This result is supported by a second GLP study which was performed
according to OECD 203 (Bogers, 1988; OECD SIDS, 2002). This study was
conducted under semi-static condictions with a sreies of concentrations
up to 1000 mg/L. The study resulted in a LC50 of 416 mg/L (nominal)
which supports the result from the key study. No analytical monitoring
was conducted. Based on the available studies it can be concluded that
aminoiminomethanesulphinic acid is of low acute toxicity to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
