Registration Dossier
Registration Dossier
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EC number: 935-454-7 | CAS number: 68516-18-7
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Based on the available structural data and phys-chem properties, it is likely that the substance is very poorly absorbed.
Key value for chemical safety assessment
Additional information
Structural assessment
The substance is a complex UVCB which contains a variety of esters, alcohols, ethers and parrafins.
Different components and functional groups within this substance could undergo a variety of Phase I metabolism reactions, for example oxidation of alcohol groups to aldehydes and/or carboxylic acids, followed by Phase II conjugation reactions. The ester components might also undergo some degree of hydrolysis to the corresponding carboxylic acid and alcohol moieties.
The Molecular Weight of the component substances would indicate that some degree of absorption is possible. Furthermore any hydrolysis of the ester components will create lower MW species which would be more easily absorbed.
Phys-chem
The substance is relatively poorly soluble in water (11.98 mg/l). The Log Pow is high (7.7). The high lipophilicity will tend to limit absorption.
Conclusion
Based on the available structural data and phys-chem properties, it is likely that the substance is very poorly absorbed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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