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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

No toxic effects at the limit of solubility of the test material in the test medium, EU Method C.2

Key value for chemical safety assessment

Additional information

The acute toxicity of the test material to the aquatic invertebrate, Daphnia magna, was investigated in a study which was conducted under GLP conditions and in accordance with the standardised guideline EU Method C.2.

During the study the Daphnia were exposed to a saturated solution of test material (prepared from a 100 mg/L dispersion of test material) for a period of 48 hours.Chemical analysis of the saturated solution showed measured concentrations to be below the limit of quantitation of the analytical method (0.27 mg/L).

Under the conditions of the study the 48-hour EC50 of the test material was determined to be in excess of 0.27 mg/L (the limit of quantitation of the analytical method used). The result suggests that the test material is not toxic up to the limit of solubility.

The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as set forth in the publication by Klimisch et al (1997).