Sodium iodide

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Data is from peer reviewed journal

Justification for type of information:

Data is from peer reviewed journal

Qualifier:

according to guideline

Guideline:

other: Refer below principle

Principles of method if other than guideline:

Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system.

GLP compliance:

no

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Daphnia magna

Details on test organisms:

SPECIES (NAME) : Daphnia magna (Water Flea)
AGE : <=24 h

Test type:

static

Water media type:

freshwater

Total exposure duration:

48 h

Hardness:

54.4 mg/L CaCO3

Test temperature:

20 degC

pH:

8.0

Dissolved oxygen:

10.1 mg/L

Salinity:

Not Reported

Details on test conditions:

ALKALINITY : 47 mg/L CaCO3
CONDUCTIVITY : 256 umhos/cm
TEST LOCATION : LAB
APPLICATION FREQ. : 1 X

Reference substance (positive control):

not specified

Key result

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

0.17 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

mortality

Remarks on result:

other: Other details not known

Validity criteria fulfilled:

not specified

Conclusions:

The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is observed to be 0.17 mg/L.

Executive summary:

Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.

Description of key information

Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

0.17 mg/L

Additional information

Various short term studies available for the test chemical were reviewed to determine the toxic nature of test chemical on the mobility of aquatic invertebrates. The studies are as mentioned below:

 

The first key study was for the determination of the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.

 

First study was supported by the second study from peer reviewed journal. Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 h old daphnia were used for the toxicity measurement. Test performed under the static system. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect was observed to be 0.23 mg/L. Thus considering the CLP Criteria for aquatic classification of the substance, it can be assumed that test chemical could exhibit toxicity to aquatic invertebrates and classified in the aquatic acute 1 classification category.

 

Similar short term toxicity of test chemical was studied on the growth of freshwater water flea daphnia magna. Test conducted under the static system for 48 hrs. <=24 hrs old daphnia magna were used as a test organism. Based on the mortality of daphnia magna by the chemical exposure for 48 hrs, the LC50 value was determine to be at 0.43 mg/l and 0.78 mg/l also with the slight changes occurs in the temperature, pH and hardness of water. Thus considering the CLP Criteria for aquatic classification of the substance, it can be consider that the test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) and classified in the aquatic acute 1 classification category.

 

Similarly aim of this study was to determine the effect of test chemical on the mobility and Floatability of test daphnia magna by providing the exposure period of 24 hrs. Test conducted under the static system. 24 h old daphnia magna were used in the study. After the exposure of test chemical with daphnia magna for 24 hrs, no effect were observed on the mobility and floating behavior at 1 mg/l. Effects i.e EC50 was observed at the concentration 13 mg/l. Thus based on the EC50 value, it can be concluded that the chemical is toxic and can be consider to be classified as aquatic chronic 3 category as per the CLP classification criteria.

 

Thus based on the all above studies, chemical consider to be toxic to the aquatic invertebrates and classified in aquatic acute category 1 as per the CLP classification criteria.