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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
Estimation 28 days NOEC value of test chemical on aquatic fish by EPI Suite ECOSAR version 1.11.
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
no
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
17.079 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: Neutral Organic SAR (Baseline Toxicity)
Validity criteria fulfilled:
not specified
Conclusions:
Based on effect of test chemical on the reproduction of the test fish, the 28 days NOEC value was estimated to be 17.079 mg/l.
Executive summary:

The long-term toxicity of the test chemical to aquatic fish was predicted using EPI Suite ECOSAR version 1.11. On the basis of effect of test chemical observed in a flow through system on the reproduction of the test organism during the 28 days exposure duration, the NOEC value for the test chemical was estimated to be 17.079 mg/l. Thus, based on the NOEC value, test chemical was considered as non-toxic to aquatic fishes and hence, considered to be 'not classified' as per the CLP classification criteria.

Description of key information

The long-term toxicity of the test chemical to aquatic fish was predicted using EPI Suite ECOSAR version 1.11. On the basis of effect of test chemical observed in a flow through system on the reproduction of the test organism during the 28 days exposure duration, the NOEC value for the test chemical was estimated to be 17.079 mg/l. Thus, based on the NOEC value, test chemical was considered as non-toxic to aquatic fishes and hence, considered to be 'not classified' as per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
17.079 mg/L

Additional information

The long-term toxicity of the test chemical to aquatic fish was predicted using EPI Suite ECOSAR version 1.11. On the basis of effect of test chemical observed in a flow through system on the reproduction of the test organism during the 28 days exposure duration, the NOEC value for the test chemical was estimated to be 17.079 mg/l. Thus, based on the NOEC value, test chemical was considered as non-toxic to aquatic fishes and hence, considered to be 'not classified' as per the CLP classification criteria.