Registration Dossier
Registration Dossier
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EC number: 203-797-5 | CAS number: 110-73-6
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.32 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.032 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 37.3 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.3 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.013 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.073 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 0.17 mg/kg food
- Assessment factor:
- 300
Additional information
Five ecotoxicology relevant studies were conducted for 2 -ethylaminoethanol. The lowest determined endpoint was based the Daphnia reproduction test that provided a NOEC of 3.2 mg/L. Suitable assessment factors have been applied to calculate PNECs for freshwater, marine water and STPs
The terrestrial toxicity compartment has been waived for 2-ethylaminoethanol on the grounds that exposure is not expected to occur and that 2-ethylaminoethanol is readily biodegradable. Under these circumstances, data for the effects of 2-ethylaminoethanol on the terrestrial compartment are considered unnecessary.
A 14 -day combined acute oral and IP study is available and an acute oral toxicity to the mouse, the lowest reported NOECoral was for the mouse (50 mg/kg)
Conclusion on classification
The lowest acute EC50value was 37.3 mg/L for the aquatic algae Pseudokirchneriella subcapitata and therefore the EC50is between 10 and <100 mg/L and therefore classification is not required
Based on the results of the Daphnia reproduction test the NOEC was considered to be 3.2 mg/L, 2 -ethylaminoethanol was considered to be readily biodegradable during testing and therefore is not expected to persist with the environment. Based on the NOEC of 3.2 mg/L classification is not required
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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