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EC number: 225-590-9
CAS number: 4948-15-6
The test substance is with high probability acutely not harmful to
The inhibition of the degradation activity of activated sludge is not
anticipated when introduced in appropriate low concentrations.
The test substance belongs to the category of perylene as indicated by
its chemical core structure. Based on this structure and the chemical
and biological stability of perylenes under environmental conditions,
data from structural analogue perylenes can be used to cover this
endpoint required under REACh if no data for the original test substance
In a GLP study following OECD guideline 203 the acute toxicity of the
test substance to fish was determined. Test fish of the species Brachydanio
rerio were exposed to the substance for 96 hours in a static test
system. At test termination a LC50 > 1350 mg/L based on measured test
substance concentrations was determined [BASF AG, 1999].
The acute toxicity of the test substance to aquatic invertebrates has
been examined in a GLP guideline study according to EEC Directive
92/32/EEC. The test animals of the species Daphnia magna were
exposed to the test substance for 48 h in a static test system set up.
At test termination an EC50 > 100 mg/l was determined [BASF SE, 1998].
The toxicity of the test substance on aquatic algae was investigated in
a GLP guideline study according to OECD 201 with Pseudokirchneriella
subcapitata [BASF SE, 2012]. The substance had no observable
inhibitory effect on algae growth up to its saturation limit in the test
media and under test conditions. The EC50 value (based on growth rate
after 72 h of exposure) was determined to be > 100 mg/L (nominal).
The acute toxicity of the analogue substance CAS 81-33-4 to aquatic
plants has been examined in a GLP guideline study according to OECD 221
with the test species Lemna gibba [BASF SE, 2012]. At test
termination after 7 d, an ECr50 > 0.007 mg/L (measured) relating to
growth rate (frond rate and dry weight, respectively) was determined.
The changes in the respiration rate of activated sludge in presence of
the test substance was investigated in a guideline study according to
OECD 209 and ISO 8192, with activated sludge as inoculum. At test
termination after 30 minutes NOEC >= 1000 mg/L (nominal) were determined
[BASF AG 1998].
All tests were run with concentrations above the water solubility of the
test substance and its analogues, respectively. Thus, no effects in the
range of the water solubility of the substance were determined.
The hazard assessment of the substance reveals neither a need to
classify the substance as dangerous to the environment, nor is it a PBT
or vPvB substance, nor are there any further indications that the
substance may be hazardous to the environment. Therefore, and for
reasons of animal welfare long-term toxicity testing in fish and aquatic
invertebrates is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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