Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-625-1 | CAS number: 123-41-1
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No information is available concerning toxicity of Choline hydroxide towards sediment organisms.
In accordance with column 2 of REACH annex X, long-term toxicity testing shall be proposed by the registrant if the results of the chemical safety assessment indicates the need to investigate further the effects of the substance and/or degradation products on sediment organisms. The choice of the appropriate test(s) depends on the outcome of the chemical safety assessment. Since it was shown in the environmental risk assessment that the RCRs for the freshwater and marine sediment are below the trigger value of 1 for all exposure scenarios, this endpoint can be waived. In addition, the substance is readily biodegradable and it can be assumed that it will be completely biologically degraded within the STP process. Furthermore, for substances not passing the STP-process but being readily, it can be assumed that they will be also biological degraded in the surface water within a short time. Therefore, tests on sediment organisms are considered as scientifically unjustified. The Predicted No Effect Concentration (PNEC) for sediment was derived using the equilibrium partitioning method (EPM) and the PNEC for freshwater, derived from experimental results. This procedure is in accordance with ECHA REACH Guidance of Information Requirements and Chemical Safety Assessment, Chapter R.10 (2008): Characterisation of dose-response for environment".
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
