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EC number: 939-379-0
CAS number: -
Doses up to and including 5000 µg per plate did not cause any bacteriotoxic effects: Total bacteria counts remained unchanged
and no inhibition of growth was observed. Substance precipitation occurred at the dose 200 µg per plate and above, such that at 5000 µg per plate, the test was no longer interpretable in Salmonella typhimurium TA 100.
BAYPLAST Yellow 5GN was investigated using the Salmonella/microsome test for point mutagenic effects in doses up to 5000 µg per plate on four Salmonella typhimurium LT2 mutants. These comprised the histidine-auxotrophic strains TA 1535, TA 100, TA 1537 and TA 98.
Evidence of mutagenic activity of BAYPLAST Yellow 5GN was not seen. No biologically relevant increase in the mutant count,
in comparison with the negative controls, was observed.
Therefore, BAYPLAST Yellow 5GN was considered to be non-mutagenic without and with S9 mix in the Salmonella/microsome
The positive controls sodium azide, nitrofurantoin, 4-nitro-l,2-phenylene diamine and 2-aminoanthracene had a marked mutagenic effect, as was seen by a biologically relevant increase in mutant colonies compared to the corresponding negative controls.
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