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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

Toxicity to microorganisms has been tested with a sample of activated sludge (from a predominantly domestic water treatment plant) in two studies over a 3 hour period at nominal concentrations from 100 - 10000 mg/l and the EC50 was > 10000 mg/l and EC0 was 700 mg/l. In another study, Psudomonas putida was exposed to varying concentrations and the 17 hour EC50 was 1400 mg/l, EC10 was 800 mg/l and EC90 was 2400 mg/l, the TGK (toxicity threshold limit) comparable to the EC3 value was 800 mg/l.

As a worst case approach, the NOEC of 700 mg/L was chosen as key parameter.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
700 mg/L

Additional information

In a study on the effect of the substance on activated sludge a inhibition of 12% was observed at 10,000 mg/L and the EC50 was > 10,000 mg/l in the other study no effects were observed up to 700 mg/l.

The result is supported by two further studies on the structural analog Ethylendiamine, propoxylated.

Toxicity of the analog substance to microorganisms has been tested with a sample of activated sludge (from a predominantly domestic water treatment plant) in two studies over a 3 hour period at nominal concentrations from 100 - 10,000 mg/l.

In a third study, Pseudomonas putida was exposed to varying concentrations and the 17 hour EC50 was 1400 mg/l, EC10 was 800 mg/l and EC90 was 2400 mg/l, the TGK (toxicity threshold limit) comparable to the EC3 value was 800 mg/l.