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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30 August - 21 September 2004
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study, conducted to GLP. No reporting of impurity identification.
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
Limited reporting detail - missing information on impurity content
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(of Directive 92/69/EEC)
Deviations:
yes
Remarks:
Limited reporting detail - missing information on impurity content
GLP compliance:
yes
Type of method:
flask method
Water solubility:
799 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
7

 Sample number  Amount of test item [g]  Added volume of water [mL]  Shaking time at 30 deg C [hours]  Analysed concentration of test item [g/L]  pH
 1 5.919  3  24  799  7.0
 2  5.931  3  24  801  7.0
 3  5.920  3  48  809  7.0
 4  5.916  3  48  790  7.0
 5  5.918  3  72  797  7.0
 6  5.908  3  72  797  7.0
Conclusions:
The water solubility of platinum(II) tetraammine diacetate was determined to be 799 g/L at a temperature of 20 deg C, indicating it to be very water soluble (> 10000 mg/L).
Executive summary:

In a guideline-compliant study, conducted to GLP, the water solubility of platinum(II) tetraammine diacetate was determined to be 799 g/L at a temperature of 20 deg C, indicating a very high degree of water solubility.

Description of key information

The water solubility of platinum(II) tetraammine diacetate was determined to be 799 g/L at a temperature of 20 deg C (Mekelburger, 2004e), indicating a very high water solubility. 
    
    
    

In a guideline-compliant study, conducted to GLP, the water solubility of platinum(II) tetraammine diacetate was determined to be 799 g/L at a temperature of 20 deg C, indicating a very high degree of water solubility.

Key value for chemical safety assessment

Water solubility:
799 g/L
at the temperature of:
20 °C

Additional information