Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Dose descriptor:
NOAEL
870 mg/kg bw/day
Additional information

No toxic effects on reproduction/fertility were noted at doses of up to 870 mg/kg.


Short description of key information:
Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test: OECD 422: NOAEL for effects on reproduction 870 mg/kg body weight

Effects on developmental toxicity

Description of key information
Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test: OECD 422: NOAEL for effects on reproduction 1000 mg/kg body weight
Effect on developmental toxicity: via oral route
Dose descriptor:
NOAEL
870 mg/kg bw/day
Additional information

No toxic effects on developmental toxicity were noted at doses of up to 870 mg/kg.

Justification for classification or non-classification

According to EU-Directive 2001/59/EC, the application of "R60" is not considered as necessary for the test item, as no toxic effects on reproduction were noted at doses of up to 870 mg/kg.