Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 905-570-2 | CAS number: -
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
There are two earthworm reproduction studies available one for p-xylene and one for mixed xylenes (CAS 1330 -20 -7; substance composition equivalent to reaction mass of ethylbenzene and mixed xylenes). The study on p-xylene reports a NOEC of 71.1 mg/kg soil dry weight and an EC50 of 88.8 mg/kg soil dry weight (intial measured concentrations) based on mortality and effect on reproduction. The study on mixed xylenes (CAS 1330 -20 -7; substance composition equivalent to reaction mass of ethylbenzene and mixed xylenes) reported a NOEC of 42.6 mg/kg soil dry weight and an EC50 of 93.2 mg/kg soil dry weight (initial measured concentrations) based on effects on reproduction.
Due to the technical challenges of testing volatile substances, a TLM-EqP modeling framework was used to support terrestrial effect values derived experimentally and are presented as supporting studies. Data from the Draft Screening Assessment Report (Environment Canada 2014) was also used. These data were considered reliable and comparable to experimentally derived values; however, were not used in the PNEC derivation in order to comply with ECHA FDL (2014) on using experimental data to derive PNEC. The hazard to soil organisms was assessed by using the experimental data.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 88.8 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 42.6 mg/kg soil dw
Additional information
Due to the technical challenges of testing volatile substances, a TLM-EqP modeling framework was used to support terrestrial effect values derived experimentally and are presented as supporting studies. The estimated 28 day LL50 values from TLM QSAR were 22.082 - 74.410 mg/kg dw and 56 day long-term effects NOELR values from TLM QSAR were 4.2 30 - 14.255 mg/kg dw.
The Draft Screening Assessment Report (Environment Canada 2014) reports for Ethylbenzene a 14 day NOEC for earthworms of 16 mg/kg dw from ESG International (2002).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
