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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
not specified
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to
Guideline:
OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
Deviations:
not specified
Qualifier:
according to
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
Deviations:
not specified
GLP compliance:
not specified
Remarks:
the test was conducted in an academic setting without GLP certification
Specific details on test material used for the study:
technical grade, no further information
Oxygen conditions:
aerobic
Inoculum or test system:
sewage, predominantly domestic, non-adapted
Details on inoculum:
- Source of inoculum/activated sludge: STP of Lüneburg, Germany (144,000 inhabitant
equivalents)
- Initial cell/biomass concentration: two drops of effluent per L
Duration of test (contact time):
28 d
Key result
Parameter:
% degradation (O2 consumption)
Value:
78.3
St. dev.:
1.6
Sampling time:
28 d
Remarks on result:
other: OECD 301D (CBT)
Key result
Parameter:
% degradation (O2 consumption)
Value:
65.9
St. dev.:
5.4
Sampling time:
28 d
Remarks on result:
other: OECD 301F (MRT)

Biodegradation test results obtained in the present study. For each experiment the % O2consumption in the two parallel bottles is given, and for valid results the average ±SD, otherwise the criterion rendering a result invalid.

Compound name

(abbreviation)

[CAS-RN]

Experiment number

OECD 301D (CBT)

OECD 301F (MRT)

O2Consumption/

ThOD [%]

Average in a valid experiment ±SD

O2Consumption/ ThOD [%]

Average in a valid experiment ±SD

TGA and derivatives

Thioglycolic acid

(TGA)

[68-11-1]

1

31.8, 45.3

38.5 ±9.5

114.4, 92.1

not valid,

criterion 1

2

49.2, 51.3

50.2 ±1.5

78.8, 94.4

86.6 ±11.1

Diammonium dithiodiglycolate

(DADTDG, TGA disulfide ammonium salt)

[68223-93-8]

1
calculated without nitrification

123.8, 106.4

115.1 ±12.3

130.0, 132.0

131.0 ±1.4

1
re-calculated with nitrification

76.6, 65.9

71.3 ±7.6

80.5, 81.7

81.1 ±0.9

2
calc. with nitrification

14.9, 29.2

22.0 ±10.1

79.4, 90.8

85.1 ±8.0

3
calc. with nitrification

90.9, 86.0

88.5 ±3.5

 

 

Dithiodiglycolic acid

(DTDGA, TGA disulfide)

[505-73-7]

1

65.9, 62.2

64.1 ±2.6

87.9, 111.2

not valid,

criterion 1

2

 

 

 

60.3, 55.7

58.0 ±3.3

2-Ethylhexyl thioglycolate

(2-EHTG)

[7659-86-1]

1*

58.3, 61.2

59.7 ±2.0

28.2, 54.7

not valid,

criterion 1

2*

 

 

18.4, 13.9

16.2 ±3.2

Isotridecyl thioglycolate

(iC13TG)a

[57417-85-3]

1**

1.4, 10.0

not valid,

criterion 4

40.9, 22.5

31.7 ±13.0

2**

14.6, 9.5

12.0 ±3.6

 

 

Glycol di(mercaptoacetate)

(GDMA)

[123-81-9]

1

62.2b

not valid,

criterion 1

62.1, 69.8

65.9 ±5.4

2

82.5, 72.4

not valid,

criterion 4

 

 

3

70.0b

not valid,

criterion 1

 

 

4

79.4, 77.1

78.3 ±1.6

 

 

Glyceryl monothioglycolatea(GMT)

[30618-84-9]

1

56.0, 50.7

53.4 ±3.7

79.8, 80.8

80.3 ±0.7

amulticonstituent substance (MCS), for details see Experimental

bresult from one test bottle only, the other one became leaky during the experiment

*due to poor solubility, this substance was directly weighed in MRT

**due to very poor solubility, this substance was directly weighed both in CBT and MRT

Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
Based on 78% biodegradation in a closed bottle test, GDMA is readily biodegradable.

Description of key information

Based on predicted 78 % biodegradation, GDMA is expected to be readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:
freshwater

Additional information