5-bromo-5-nitro-1,3-dioxane

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Analytical monitoring:

yes

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Test type:

static

Limit test:

no

Total exposure duration:

72 h

Reference substance (positive control):

yes

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

0.265 mg/L

Nominal / measured:

meas. (geom. mean)

Basis for effect:

growth rate

Key result

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

0.088 mg/L

Nominal / measured:

meas. (geom. mean)

Basis for effect:

growth rate

Validity criteria fulfilled:

yes

Conclusions:

With an EC50 (growth) Bronidox K turned out to be very toxic to aquatic algea. Based on the observed EC10 (growth) of 0.088 mg/l long-term exposure to Bronidox K is toxic for algae.

Description of key information

The 72h ErC50 (growth) for algae ( Pseudokirchneriella subcapitata) exposed to the test substance was 0.265 mg/L based upon the measured geometric mean. Based on the observed EC10 (growth) of 0.088 mg/l long-term exposure to the test substance is toxic for algae.

Key value for chemical safety assessment

EC50 for freshwater algae:

0.265 mg/L

EC10 or NOEC for freshwater algae:

0.088 mg/L