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Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28th March - 6th June 1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
Sample solutions of increasing concentrations were prepared in nine separate flasks. After addition of glass double-distilled water to the flasks, they were shaken at approximately 30 °C for at least 24 hours and after standing at 20 °C for approximately 24 hours, the contents of the flasks were visually inspected for evidence of undissolved material.
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
> 47.5 - < 50 other: %w/w
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 4.7
Details on results:
At concentrations up to and including 47.5 %w/w, clear yellow solutions were formed after standing for 24 hours at 20 °C. At 50.0 %w/w undissolved item was observed after standing.
Conclusions:
The water solubility of the test item was between 47.5 and 50.0 % w/w.
Executive summary:

The standard EU test method A.6 was not applicable to this test item. Due to the viscous nature, high water solubility and difficulties associated with filtration of the test solutions it was considered to be more appropriate to estimate the water solubility by visual inspection. Sample solutions ranging from 10 - 60 %w/w were prepared in nine separate flasks. After addition of glass double-distilled water to the flasks, they were shaken at approximately 30 °C for at least 24 hours and after standing at 20 °C for approximately 24 hours, the contents of the flasks were visually inspected for evidence of undissolved material. The water solubility of the test item was between 47.5 and 50.0 % w/w.

Description of key information

The water solubility is estimated to be between 475 and 500 g/L.

Key value for chemical safety assessment

Water solubility:
475 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item was visually assessed after shaking 9 different flasks containing the test item at concentrations from 10 - 60 %w/w for 24 hours at 30 °C, followed by standing for 24 hours at 20 °C. The water solubility was found to be between 47.5 - 50.0 %w/w (475 - 500 g/L).