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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Analytical monitoring:
yes
Vehicle:
yes
Test organisms (species):
Daphnia magna
Details on test organisms:
Daphnia magna Straus originates from a clone breeding of the German Federal Environmental Agency, department V 3.2, Berlin
Test type:
static
Water media type:
freshwater
Total exposure duration:
48 h
Test temperature:
20.6 to 21.4°C
pH:
7.5-8.7
Dissolved oxygen:
7.59 to 8.37 mg/L
Nominal and measured concentrations:
Nominal= 6.25, 12.5, 25,50,100, 200
Reference substance (positive control):
yes
Remarks:
potassium dichromate
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
14.08 mg/L
Nominal / measured:
nominal
Remarks on result:
other: 98% CL
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
6.25 mg/L
Nominal / measured:
nominal
Duration:
48 h
Dose descriptor:
EC10
Effect conc.:
12.15 mg/L
Nominal / measured:
nominal

The recovery rates ranged from 97.3% to 120.0%. The highest decrease of the test concentration was -1.5%. According to the analytical results SLMI was stable during the test course.

Validity criteria fulfilled:
yes
Conclusions:
In a study performed to OECD 202, SLMI was found to have an EC50 (48h) of 14.1 mg/L
Executive summary:

In a study performed to OECD 202, SLMI was found to have an EC50 (48h) of 14.1 mg/L

Description of key information

In a study performed to OECD 202, SLMI was found to have an EC50 (48h) of 14.1 mg/L


In a study performed to EPA OPPTS 850.1010 the read across substance SCMI was found to have an EC50 of 257.86 mg/l (nominal concentration)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
14.1 mg/L

Additional information

In a key study performed to OECD 202, SLMI was found to have an EC50 (48h) of 14.1 mg/L (nominal concentrations)

In a supporting study performed to EPA OPPTS 850.1010 on the read across material SCMI, an EC50 of 257.86 mg/l (95% C.I 194.51-341.83 mg/l) based on nominal concentrations was derived