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EC number: 695-101-5 | CAS number: 1275611-65-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: long-term
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- Long term daphnia and sediment tests are available for 8 different cationic surfactants. The results of these studies were compared to the via EPM calculated effects as justification of the use of the EPM for cationic surfactants. For 5 out of the 8 the EPM predicted the EC10 for sediment organisms more conservatively than what was observed in the sediment test without applying the additional safety factor of 10 to compensate for ingestion. After including the additional AF (of 10), for all 8 substances the EPM was found to be more conservative than the observed sediment toxicity. The Kp sups-water for these substances ranged from 1040 L/kg to 20100 L/kg.
New data sediment and daphnia data on cationic surfactants are frequently generated and will be added to the dataset in the end to generate sufficient support using the appropriate ECHA guideline to report the respective information.. - Executive summary:
Aquatic PNEC is used to calculate the benthic PNEC using a Kpsusp-sed of 3526 L/kg.
Reference
Description of key information
No benthic test data is available for N-C16-18-alkyl-(even numbered, C18 unsaturated) trimethylpropane-1,3 -diamine. The PNEC for benthic organisms is therefore calculated applying the equilibrium partitioning method using a Kpsusp-sed (or Kdsusp-sed) of 3526 L/kg
The EPM based benthic PNEC (without the correction for additional uptake via food) of 1.07 mg/kg dw
Distribution constants for for N-C16-18-alkyl-(even numbered, C18 unsaturated) trimethylpropane-1,3 -diamine as used in the calculation of the PNECsed.
Kpsoil |
1763 L/kg |
Ksoil-water |
2646 m3/m3 |
Kpsusp |
3526 L/kg |
Ksusp-water |
882 m3/m3 |
Kpsed |
1763 L/kg |
Ksed-water |
882 m3/m3 |
Since PNECfreshwater is based on the bulk concentration, a recalculation was necessary to PNECfreshwaterdissolved before application of the equilibrium partitioning method. The following equation was used:
PNECfreshwaterdissolved= PNECfreshwaterbulk/ (1 + Kpsusp-sed * SUSPwater*10-6)
Where:
PNECfreshwaterbulk= 0.32 µg/L
Kpsusp-sed = 3526 L/kg
SUSPwater= 15 mg/L.
The resulting PNECfreshwaterdissolved= 0.304 µg/L.
The PNECsed is then calculated using the equations detailed in REACH guidance R.16:
PNECsed = Ksusp-sed-water* PNECaquatic dissolved* 1000 * 1 / RHOsed
Where: PNECaquatic-dissolved = 0.304 µg/L
Ksusp-sed-water = 882 m3/m3
RHOsed = 1150 kg/m3
PNECsed-EPM = 0.233 mg/kg ww
= 1.07 mg/kg dw
Note that an additional AF of 10 is not yet applied as this is in general automatically applied by CHESAR
Long term daphnia and sediment tests are available for 8 different cationic surfactants. The results of these studies were compared to the via EPM calculated effects as justification of the use of the EPM for cationic surfactants. For 5 out of the 8 the EPM predicted the EC10 for sediment organisms more conservatively than what was observed in the sediment test without applying the additional safety factor of 10 to compensate for ingestion. After including the additional AF (of 10), for all 8 substances the EPM was found to be more conservative than the observed sediment toxicity. The Kp sups-water for these substances ranged from 1040 L/kg to 20100 L/kg.
Name | CAS number | Long term daphia NOEC/EC10 dissolved (µg/L) | EPM data sediment | Ratio observed/predicted NOEC/EC10 | |||
Kpsusp-water (L/kg) | AF for ingestion | Observed Benthic NOEC/EC10 (mg/kg dw) | Predicted Benthic NOEC/EC10 using the EPM (µg/L) | ||||
Amines, N-C16-18-alkyl (evennumbered) propane-1,3-diamine | 133779-11-0 | 315.08 | 1040 | y | 86 | 32.88 | 2.62 |
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate | 102047-27-8 | 87.37 | 4020 | y | 134 | 35.15 | 3.81 |
Quaternary ammonium compounds, C20-22-alkyltrimethyl, chlorides | 68607-24-9 | 124.61 | 1813.5 | y | 62.5 | 22.64 | 2.76 |
2,2'-(octadec-9-enylimino)bisethanol | 25307-17-9 | 9.62 | 7460 | n | 101.2 | 71.82 | 1.41 |
Quaternary ammonium compounds, di-C12-18-alkyldimethyl, chlorides | 68391-05-9 | 8.55 | 16800 | n | 320 | 143.61 | 2.23 |
C16-18-(even numbered, C18-unsaturated)-alkylamines | 68037-95-6 | 12.73 | 1394 | n | 188 | 17.80 | 10.56 |
Quaternary ammonium compounds, di-C10-alkyldimethyl, chlorides | 7173-51-9 | 14.00 | 20098.8 | n | 530 | 281.43 | 1.88 |
C12-16 alkyldimethylbenzylammonium chloride | 68424-85-1 | 4.15 | 16778.8 | n | 520 | 278.53 | 1.87 |
New data sediment and daphnia data on cationic surfactants are frequently generated and will be added to the dataset in the end to generate sufficient support using the appropriate ECHA guideline to report the respective information..
It should be noted that real measured sorption data are used which are not normalized to the organic matter content of the soils and that for both sediment and soil the same Kd is used. For suspended matter however the Kd is doubled to compensate for the additional sorption due to a higher content of small particles.
Key value for chemical safety assessment
Additional information
PNECsed-EPM = 0.233 mg/kg ww = 1.07 mg/kg dw
Note that an additional AF of 10 is not yet applied as this is in general automatically applied by CHESAR
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