Registration Dossier
Registration Dossier
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EC number: 208-197-7 | CAS number: 515-40-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- 1. SOFTWARE
EPI-SUITE EPA (USA)
2. MODEL (incl. version number)
BIOWIN v4.10
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
SMILES: CC(C)(CCl)c1ccccc1
CAS: 515-40-2
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
The QMRF is available in "Attached justification".
5. APPLICABILITY DOMAIN
The QPRF is available in "Attached justification".
6. ADEQUACY OF THE RESULT
The QPRF is available in "Attached justification". - Guideline:
- other: REACH Guidance on QSARs R.6
- Principles of method if other than guideline:
- Boethling, R.S., Lynch, D.G., Jaworska, J.S., Tunkel, J.L., Thom, G.C., Webb, S. 2004. Using BIOWIN, Bayes, and batteries to predict ready biodegradability. Environ. Toxicol. Chem. 23:911-920.
- GLP compliance:
- no
- Specific details on test material used for the study:
- SMILES: CC(C)(CCl)c1ccccc1
- Key result
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The substance is predicted to be not readily biodegradable by EPI-Suite BIOWIN v4.10.
- Executive summary:
The substance is predicted to be not readily biodegradable by EPI-Suite BIOWIN v4.10.
Reference
BIOWIN v4.10 predicted that the test item is not readily biodegradable.
Description of key information
Key study: Internationally accepted calculation method, EPI-Suite EPA (USA). The substance is predicted to be not readily biodegradable by EPI-Suite BIOWIN v4.10.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
