Registration Dossier
Registration Dossier
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EC number: 700-403-8 | CAS number: -
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: SOP E211 based on OSP AR / P ARC OM Protocols on Methods for the Testing of Chemicals Used in the Offshore Industry 2006 Part A: A sediment bioassay using an amphipod Corophium sp.
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Details on test material:
- - Purity: not reported as such
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Corophium volutator
Study design
- Study type:
- laboratory study
- Test type:
- static
- Water media type:
- saltwater
- Type of sediment:
- natural sediment
Exposure duration
- Duration:
- 10 d
- Exposure phase:
- total exposure duration
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 12 497 mg/kg sediment dw
- Nominal / measured:
- nominal
- Duration:
- 10 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 6 251 mg/kg sediment dw
- Nominal / measured:
- nominal
Any other information on results incl. tables
The water quality measurements of the test solutions were within acceptable limits during the study.
None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.
Applicant's summary and conclusion
- Conclusions:
- 10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment.
- Executive summary:
The 10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment by the non-linear interpolation method in ToxCalc™ Version 5.0.
The highest no-observed effect concentration (NOEC) after 10-days was determined to be 6251 mg/kg dry sediment using Fisher's Exact test in ToxCalc™ Version 5.0.
The water quality measurements of the test solutions were within acceptable limits during the study.
None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.
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