Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: limited but acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975
Report date:
1975

Materials and methods

Principles of method if other than guideline:
Method: other acute dermal toxicity study
GLP compliance:
no
Test type:
other: acute dermal toxicity study

Test material

Constituent 1
Chemical structure
Reference substance name:
Zinc di(benzothiazol-2-yl) disulphide
EC Number:
205-840-3
EC Name:
Zinc di(benzothiazol-2-yl) disulphide
Cas Number:
155-04-4
Molecular formula:
C7H5NS2.1/2Zn
IUPAC Name:
zinc 1,3-benzothiazole-2-thiolate
Details on test material:
Bantex

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
corn oil
Duration of exposure:
24 h
Doses:
7940
No. of animals per sex per dose:
2
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 7 940 mg/kg bw
Based on:
test mat.
Remarks on result:
other: clinical signs like reduced appetite and activity

Any other information on results incl. tables

Mortality: no death occured during the study (0/2)

Clinical signs observed: reduced appetite and activity (two to four days)

Gross autopsy (survivors): viscera appeared normal

Applicant's summary and conclusion