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EC number: 266-041-3
CAS number: 65997-06-0
data is being read across from the source study that tested Resin and
rosin acids, hydrogenated, potassium salt based on category read across
that is explained in the category justification document attached in
Section 13 of the dossier.
In a reverse gene mutation assay in
bacteria, strains TA 98, TA 100, TA 1535 and TA 1537 of S. typhimurium
and strain WP2 uvr A of E. coli were exposed to Resin acids and Rosin
acids, hydrogenated, potassium salts in sterile distilled water at
concentrations of 50, 150, 500, 1500 and 5000 µg/plate in the presence
and absence of mammalian metabolic activation using the direct plate
incorporation method. At the highest concentration
tested, a white opaque film was observed but this did not affect the
scoring of revertant colonies. There was no evidence
of an increase in induced mutant colonies over background with the test
substance at any concentration tested, while the positive, negative and
vehicle controls induced the appropriate responses in the corresponding
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