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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 16 - October 13, 2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
< 1 mg/L
Temp.:
20 °C
pH:
8

The results for the samples were based on the test substance
related compound with m/z 395.3 amu. No response of the
test substance related compound was detected in the test
samples. It demonstrated that the water solubility of the
test substance was below the limit of quantification (LOQ)
of the analytical method (i.e. < 1 mg/l).

In all test samples, a small response of a test substance
related compound with a m/z value of 669.9 amu was observed.
The response was significantly below the response of the
lowest calibration solution. Based on this it was concluded
that the water solubility of the compound was < 1 mg/l.

Conclusions:
It was concluded that the water solubility of the compound was < 1 mg/l.

Description of key information

The water solubility was determined using the flask method and the study was performed according to OECD Guideline 105/EU method A.6 and GLP principles.

Key value for chemical safety assessment

Water solubility:
1 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the substance was determined to be <1 mg/l.